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Volumn 13, Issue 10, 2003, Pages 1683-1686

Identification of potent and broad-spectrum antibiotics from SAR studies of a synthetic vancomycin analogue

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; LEAD; VANCOMYCIN;

EID: 0038215381     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00243-9     Document Type: Article
Times cited : (20)

References (21)
  • 1
    • 0034680167 scopus 로고    scopus 로고
    • (a) Walsh C.T. Nature. 406:2000;775.
    • (2000) Nature , vol.406 , pp. 775
    • Walsh, C.T.1
  • 3
    • 0036682463 scopus 로고    scopus 로고
    • (c) Pearson H. Nature. 418:2002;469.
    • (2002) Nature , vol.418 , pp. 469
    • Pearson, H.1
  • 10
    • 85031187838 scopus 로고    scopus 로고
    • The synthesis of the macrocycle 2 is described in the Supporting Information of ref 4.
  • 11
    • 85031182280 scopus 로고    scopus 로고
    • The following amino acid inputs were used: D- and L-isomers of Ala, Asn, Glu, His, Lys, N-Me-Phe, Phe, Pro, Thr, tetrahydroisoquinoline-3-carboxylic acid (Tic), Trp, Tyr, Val; the L-isomer of diaminopropionic acid (Dapa) and 1,2,3,4- tetrahydronorharman-3-carboxylic acid (Tpi); and racemic 1,3-dihydroisoindole carboxylic acid (Disc) and 1-aminocyclohexane-carboxylic acid (Achc).
  • 12
    • 85031190128 scopus 로고    scopus 로고
    • Compounds were tested according to NCCLS protocols. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically, Approved Standard, 5th ed.; NCCLS Document M7-A5; National Committee for Clinical Laboratory Standards: Wayne, PA, 2000.
  • 14
    • 85031190454 scopus 로고    scopus 로고
    • World patent 9 738 706, 1997
    • (b) Stack, D. R., Thompson, R. C. World patent 9 738 706, 1997.
    • Stack, D.R.1    Thompson, R.C.2
  • 18
    • 85031182214 scopus 로고    scopus 로고
    • Ref 5c
    • (b) Ref 5c.
  • 21
    • 0033574743 scopus 로고    scopus 로고
    • For a discussion of an alternative mode of action of monomeric vancomycin derivatives against resistant bacteria, see:
    • For a discussion of an alternative mode of action of monomeric vancomycin derivatives against resistant bacteria, see: Ge M., Chen Z., Onishi H.R., Kohler J., Silver L.L., Kerns R., Fukuzawa S., Thompson C., Kahne D. Science. 284:1999;507.
    • (1999) Science , vol.284 , pp. 507
    • Ge, M.1    Chen, Z.2    Onishi, H.R.3    Kohler, J.4    Silver, L.L.5    Kerns, R.6    Fukuzawa, S.7    Thompson, C.8    Kahne, D.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.