Quantification of UVR-induced DNA damage: Global- versus gene-specific levels of thymine dimers

Journal of Immunological Methods

Volumn 277, Issue 1-2, 2003, Pages 27-37

  Karakoula, Aikaterini ^a   Evans, Mark D ^a   Podmore, Ian D ^b   Hutchinson, Peter E ^c   Lunec, Joseph ^a   Cooke, Marcus S ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF SALFORD   (United Kingdom)

^c LEICESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Gas chromatography mass spectrometry; Genes; Immunoassay; PCR; Polyclonal antiserum; Thymine dimers

Indexed keywords

DIMER; IMMUNOGLOBULIN G479; THYMINE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA EXTRACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GAS CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; ONCOGENE H RAS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ULTRAVIOLET RADIATION;

MAMMALIA;

EID: 0038208191     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(03)00122-4     Document Type: Article

References (43)

1. Ahmad J., Cooke M.S., Hussieni A., Evans M.D., Patel K., Burd R.M., Bleiker T.O., Hutchinson P.E., Lunec J. Urinary thymine dimers and 8-oxo-2′-deoxyguanosine in psoriasis. FEBS Lett. 460:1999;533-549.
2. Alcalay J., Freeman S.E., Golberg L.H., Wolf J.E. Excision repair of pyrimidine dimers induced by simulated solar radiation in the skin of patients with basal cell carcinoma. J. Invest. Dermatol. 95:1990;506-509.
3. Bohr V.A. Gene specific DNA repair. Carcinogenesis. 12:1991;1983-1991.
4. Bohr V.A., Okumoto D.S. Analysis of frequency of pyrimidine dimers in specific genomic sequences. Friedberg E.C., Hanawalt P.C. DNA Repair: A Laboratory Manual of Research Procedures. 1988;347-366 Marcel Dekker, New York.
5. Bohr V.A., Smith C.A., Okumoto D.S., Hanawalt P.C. DNA repair in an active gene: removal of pyrimidine dimers from DHFR gene of CHO cells is much more efficient than in the genome overall. Cell. 40:1985;359-369.
6. Bohr V.A., Phillips D.H., Hanawalt P.C. Heterogenous DNA damage and repair in the mammalian genome. Cancer Res. 47:1987;6426-6436.
7. Brennand J., Margison G.P. Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harbouring the Escherichia coli alkyltransferase gene. Proc. Natl. Acad. Sci. U. S. A. 83:1986;6292-6296.
8. Cadet J., Vigny P. Photochemistry of nucleic acids. Morrison H. Bioorganic Photochemistry. 1990;1-272 Wiley, New York.
9. Cadet J., Genter N.E., Rozga B., Paterson M.C. Rapid quantitation of ultraviolet-induced thymine-containing dimers in human cell DNA by reversed-phage high-performance liquid chromatography. J. Chromatogr. 280:1983;99-108.
10. Cadet J., Voituriez L., Grand A., Hruska F.E., Vigny P., Kan L.S. Recent aspects of the photochemistry of nucleic acids and related model compounds. Biochimie. 67:1985;277-292.
11. Cooke, M.S., 1997. Immunological investigation of UV-induced DNA damage. PhD thesis, University of Leicester, Leicester.
12. Cooke M.S., Mistry N., Wood C., Herbert K.E., Lunec J. Immunogenicity of DNA damage by reactive oxygen species - implications for anti-DNA antibodies in Lupus. Free Radic. Biol. Med. 22:1997;151-159.
13. Denissenko M.F., Venkatachalam S., Yamasaki E.F., Wani A.A. Assessment of DNA damage and repair in specific genomic regions by quantitative immuno-coupled PCR. Nucleic Acids Res. 22:1994;2351-2359.
14. Denissenko M.F., Pao A., Tang M., Pfeifer G.P. Preferential formation of benzo(α)pyrene adducts at lung cancer mutational hotspots in p53. Science. 27:1996;430-432.
15. Dizdaroglu M. Chemical determination of free radical-induced damage to DNA. Free Radic. Biol. Med. 10:1991;225-242.
16. Douki T., Court M., Sauvaigo S., Odin F., Cadet J. Formation of the main UV-induced thymine dimeric lesions within isolated and cellular DNA as measured by high performance liquid chromatography-tandem mass spectrometry. J. Biol. Chem. 257:2000;11678-11685.
17. Friedberg E.C. DNA Repair. 1985;123 Freeman, New York.
18. Gao S., Druin R., Holmquist G.P. DNA repair rates mapped along the human PKG1 gene at nucleotide resolution. Science. 263:1994;1438-1440.
19. Gloster H.M., Brodland D.G. The epidemiology of skin cancer. Dermatol. Surg. 22:1996;217-226.
20. Govan H.L., Valles-Ayoub Y., Braun J. Fine-mapping of DNA damage and repair in specific genomic segments. Nucleic Acids Res. 18:1990;3823-3830.
21. Hanawalt P.C. Preferential repair of damage in actively transcribed DNA sequences in vivo. Genome. 31:1989;605-611.
22. Herbert K.E., Mistry N., Griffiths H.R., Lunec J. Immunochemical detection of sequence-specific modifications to DNA by UV light. Carcinogenesis. 15:1994;2517-2521.
23. Hochleitner K., Thomale J., Nikitin A.Y., Rajewsky M.F. Monoclonal antibody-based, selective isolation of DNA fragments containing an alkylated base to be quantified in defined gene sequences. Nucleic Acids Res. 19:1991;4467-4472.
24. Jennerwein M.M., Eastman A. A polymerase chain reaction-based method to detect cisplatin adducts in specific genes. Nucleic Acids Res. 19:1991;6209-6214.
25. Kalinowski D.P., Illenye S., Van Houten B. Analysis of DNA damage and repair in murine leukaemia L1210 cells using a quantitative polymerase chain reaction. Nucleic Acids Res. 20:1992;3485-3494.
26. Leavine L., Seaman E., Hammerschlag E., Vunakis H.V. Antibodies to photoproducts of deoxyribonucleic acids irradiated with ultraviolet light. Science. 153:1966;1666-1667.
27. Love J.D., Minton K.W. Ultraviolet-induced dimerisation of non-adjacent pyrimidines in poly[d(A-T)]. J. Biol. Chem. 267:1992;24953-94959.
28. Mellon I., Bohr V.A., Smith C.A., Hanawalt P.C. Preferential DNA repair of an active gene in human cells. Proc. Natl. Acad. Sci. U. S. A. 83:1986;8878-8882.
29. Nataraj A.J., Trent J.C., Ananthaswamy H.N. p53 mutations and photocarcinogenesis. Photochem. Photobiol. 62:1995;218-230.
30. Peak M.J., Peak J.G. Solar-ultraviolet-induced damage to DNA. Photodermatology. 6:1989;1-15.
31. Pfeifer G.P., Drouin R., Riggs A.D., Holmquist G.P. In vivo mapping of a DNA adduct at nucleotide resolution: detection of pyrimidine (6-4) photoproducts by ligation-mediated polymerase chain reaction. Proc. Natl. Acad. Sci. U. S. A. 88:1991;1374-1378.
32. 32P-postlabelling assay. Mutat. Res. 378:1997;1-12.
33. Podmore I.D., Cooke M.S., Herbert K.E., Lunec J. Quantitative determination of cyclobutane thymine dimers in DNA by stable isotope-dilution mass spectrometry. Photochem. Photobiol. 64:1996;310-315.
34. Rodriguez H., Drouin R., Holmquist G.P., O'Connor T.R., Boiteux S., Laval J., Doroshow J.H., Akman S.A. Mapping of copper/hydrogen peroxide-induced DNA damage at nucleotide resolution in human genomic DNA by ligation-mediated polymerase chain reaction. J. Biol. Chem. 21:1995;17633-17640.
35. 2 alone or with UVB or UVA radiation. Photochem. Photobiol. 64:1996;117-122.
36. Seaman E., Vunaki V.A., Levine L. Serological estimation of thymine dimers in the deoxyribonucleic acid of bacterial and mammalian cells following irradiation with ultraviolet light and postirradiation repair. J. Biol. Chem. 247:1972;5709-5715.
37. Seawell P.C., Smith C.A., Ganesan A.K. T4 determines a DNA glycosylase specific for pyrimidine dimers in DNA. J. Virol. 35:1980;790-797.
38. Sutherland B.M., Shih A.G. Quantitation of pyrimidine dimer contents of nonradioctive deoxyribonucleic acid by electrophoresis in alkaline agarose gels. Biochemistry. 22:1983;745-749.
39. 6-ethylguanine in transcribed and non-transcribed genes of the rat. J. Biol. Chem. 269:1994;1681-1686.
40. Tornaletti S., Rozek D., Pfeifer G.P. The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer. Oncogene. 8:1993;2051-2057.
41. Tyrrell R.M., Kvam E. Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation. Carcinogenesis. 18:1997;2379-2384.
42. Wani A.A., Arezina J. Immunoanalysis of ultraviolet radiation induced DNA damage and repair within specific gene segments of plasmid DNA. Biochim. Biophys. Acta. 1090:1991;195-203.
43. 4-ethylthymidine in alkylated DNA: repair of minor miscoding base in human cells. Carcinogenesis. 8:1987;1137-1144.