The antibiotic activity of cationic linear amphipathic peptides: Lessons from the action of leucine/lysine copolymers on bacteria of the class Mollicutes

European Journal of Biochemistry

Volumn 270, Issue 10, 2003, Pages 2207-2217

  Béven, Laure ^a   Castano, Sabine ^b   Dufourcq, Jean ^b   Wieslander, Åke ^c   Wróblewski, Henri ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

^b CNRS   (France)

^c STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Amphipathic peptides; Antibacterial activity; Bacterial cell death; Membrane depolarization; Mollicutes

Indexed keywords

ANTIBIOTIC AGENT; CATIONIC LINEAR AMPHIPATHIC PEPTIDE DERIVATIVE; CHOLESTEROL; COPOLYMER; LEUCINE; LIPID; LYSINE; MELITTIN; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; WATER;

ACHOLEPLASMA; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; BETA SHEET; CELL DEATH; CELL WALL; CHEMICAL COMPOSITION; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG POTENCY; ERYTHROCYTE MEMBRANE; GROWTH INHIBITION; HYDROPHOBICITY; LIPID BILAYER; MEMBRANE DEPOLARIZATION; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MOLECULAR SIZE; MOLLICUTES; MYCOPLASMA; NONHUMAN; PEPTIDE ANALYSIS; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; RESIDUE ANALYSIS; SPIROPLASMA; STRUCTURE ACTIVITY RELATION; THICKNESS;

ANTI-BACTERIAL AGENTS; CATIONS; CELL DEATH; CELL MEMBRANE; CHOLESTEROL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROGEN-ION CONCENTRATION; LYSINE; MELITTEN; MEMBRANE POTENTIALS; MOLLICUTES; PEPTIDES; POLYMERS; PROTEIN STRUCTURE, SECONDARY; SPIROPLASMA; TIME FACTORS;

ACHOLEPLASMA; BACTERIA (MICROORGANISMS); MOLLICUTES; MYCOPLASMA; MYCOPLASMATALES; SPIROPLASMA;

EID: 0038192455     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03587.x     Document Type: Article

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