Radiation therapy plus tamoxifen versus tamoxifen alone after breast-conserving surgery in postmenopausal women with stage I breast cancer: A decision analysis

Journal of Clinical Oncology

Volumn 21, Issue 12, 2003, Pages 2260-2267

  Punglia, Rinaa S ^a   Kuntz, Karen M ^a   Lee, Jason H ^a   Recht, Abram ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TAMOXIFEN; ANTIESTROGEN; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; ESTROGEN RECEPTOR;

ADULT; AGED; ARTICLE; BREAST CANCER; BREAST SURGERY; CANCER MORTALITY; CANCER RECURRENCE; CANCER RISK; CANCER STAGING; CANCER SURVIVAL; CASE REPORT; DISEASE COURSE; FEMALE; HUMAN; POSTMENOPAUSE; PRIORITY JOURNAL; ADJUVANT CHEMOTHERAPY; ADJUVANT THERAPY; BREAST TUMOR; DECISION SUPPORT SYSTEM; DISEASE FREE SURVIVAL; MIDDLE AGED; MULTIMODALITY CANCER THERAPY; PROBABILITY; SURVIVAL;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS, HORMONAL; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; DECISION SUPPORT TECHNIQUES; DISEASE-FREE SURVIVAL; ESTROGEN ANTAGONISTS; FEMALE; HUMANS; MARKOV CHAINS; MIDDLE AGED; POSTMENOPAUSE; RADIOTHERAPY, ADJUVANT; RECEPTORS, ESTROGEN; SURVIVAL ANALYSIS; TAMOXIFEN;

EID: 0038149405     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2003.07.072     Document Type: Article

References (50)

1. Early Breast Cancer Trialists' Collaborative Group: Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: An overview of the randomised trials. Lancet 355:1757-1770, 2000
2. Shapiro CL, Recht A: Side effects of adjuvant treatment of breast cancer. N Engl J Med 344:1997-2008, 2001
3. Veronesi U, Luini A, Del Vecchio M, et al: Radiotherapy after breast-preserving surgery in women with localized cancer of the breast. N Engl J Med 328:1587-1591, 1993
4. Nemoto T, Patel JK, Rosner D, et al: Factors affecting recurrence in lumpectomy without irradiation for breast cancer. Cancer 67:2079-2082, 1991
5. Clark RM, Whelan T, Levine M, et al: Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: An update-Ontario Clinical Oncology Group. J Natl Cancer Inst 88:1659-1664, 1996
6. Veronesi U, Salvadori B, Luini A, et al: Breast conservation is a safe method in patients with small cancer of the breast: Long-term results of three randomised trials on 1,973 patients. Eur J Cancer 31A:1574-1579, 1995
7. Fisher ER, Anderson S, Redmond C, et al: Ipsilateral breast tumor recurrence and survival following lumpectomy and irradiation: Pathological findings from NSABP protocol B-06. Semin Surg Oncol 8:161-166, 1992
8. Liljegren G, Lindgren A, Bergh J, et al: Risk factors for local recurrence after conservative treatment in stage I breast cancer: Definition of a subgroup not requiring radiotherapy. Ann Oncol 8:235-241, 1997
9. Lumachi F, Ermani M, Brandes AA, et al: Predictive value of different prognostic factors in breast cancer recurrences: Multivariate analysis using a logistic regression model. Anticancer Res 21:4105-4108, 2001
10. Forrest AP, Stewart HJ, Everington D, et al: Randomised controlled trial of conservation therapy for breast cancer: 6-year analysis of the Scottish trial-Scottish Cancer Trials Breast Group. Lancet 348:708-713, 1996
11. Fisher B, Anderson S, Redmond CK, et al: Reanalysis and results after 12 years of follow-up in a randomized clinical trial comparing total mastectomy with lumpectomy with or without irradiation in the treatment of breast cancer. N Engl J Med 333:1456-1461, 1995
12. Fisher ER, Sass R, Fisher B, et al: Pathologic findings from the National Surgical Adjuvant Breast Project (protocol 6): II. Relation of local breast recurrence to multicentricity. Cancer 57:1717-1724, 1986
13. Early Breast Cancer Trialists' Collaborative Group: Tamoxifen for early breast cancer: An overview of the randomised trials. Lancet 351:1451-1467, 1998
14. Fisher B, Dignam J, Bryant J, et al: Five versus more than five years of tamoxifen therapy for breast cancer patients with negative lymph nodes and estrogen receptor-positive tumors. J Natl Cancer Inst 88:1529-1542, 1996
15. Dalberg K, Johansson H, Johansson U, et al: A randomized trial of long term adjuvant tamoxifen plus postoperative radiation therapy versus radiation therapy alone for patients with early stage breast carcinoma treated with breast-conserving surgery: Stockholm Breast Cancer Study Group. Cancer 82:2204-2211, 1998
16. Hughes KS, Schnaper L, Berry D, et al: Comparison of lumpectomy plus tamoxifen with and without radiotherapy (RT) In women 70 years of age of older who have clinical stage I, estrogen receptor positive (ER+) breast carcinoma. Proc Am Soc Clin Oncol 20:24a, 2001 (abstr 93)
17. Fyles A, Manchul L, McCready D, et al: Preliminary results of a randomized study of tamoxifen alone or tamoxifen and breast radiation in women over 50 years of age with T1/2 N0 disease. Int J Radiat Oncol Biol Phys 51:106, 2001 (suppl I)
18. Sauer R: Adjuvant radiotherapy after breast conserving surgery for breast cancer: Pro. Eur J Cancer 36:1073-1078, 2000
19. Fisher B, Bryant J, Dignam JJ, et al: Tamoxifen, radiation therapy, or both for prevention of ipsilateral breast tumor recurrence after lumpectomy in women with invasive breast cancers of one centimeter or less. J Clin Oncol 20:4141-4149, 2002
20. NIH Consensus Development Conference on the Treatment of Early-Stage Breast Cancer: Bethesda, Maryland, June 18-21, 1990. J Natl Cancer Inst Monogr 11:1-187, 1992
21. Sonnenberg FA, Beck JR: Markov models in medical decision making: A practical guide. Med Decis Making 13:322-338, 1993
22. Recht A, Come SE, Troyan SL, et al: Local-regional recurrence after mastectomy or breast conserving surgery, in Harris, JR (ed): Diseases of the Breast. Philidelphia, PA, Lippincott Williams & Wilkins, 1999, pp 731-748
23. Fisher B, Dignam J, Wolmark N, et al: Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: Findings from National Surgical Adjuvant Breast and Bowel Project B-17. J Clin Oncol 16:441-452, 1998
24. Fisher B, Costantino JP, Wickerham DL, et al: Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 90:1371-1388, 1998
25. Hankey BF, Curtis RE, Naughton MD, et al: A retrospective cohort analysis of second breast cancer risk for primary breast cancer patients with an assessment of the effect of radiation therapy. J Natl Cancer Inst 70:797-804, 1983
26. Storm HH, Jensen OM: Risk of contralateral breast cancer in Denmark 1943-80. Br J Cancer 54:483-492, 1986
27. Boice JD Jr, Harvey EB, Blettner M, et al: Cancer in the contralateral breast after radiotherapy for breast cancer. N Engl J Med 326:781-785, 1992
28. Recht A, Houlihan MJ: Axillary lymph nodes and breast cancer: A review. Cancer 76:1491-1512, 1995
29. Pierce SM, Recht A, Lingos TI, et al: Long-term radiation complications following conservative surgery (CS) and radiation therapy (RT) in patients with early stage breast cancer. Int J Radiat Oncol Biol Phys 23:915-923, 1992
30. Taghian A, de Vathaire F, Terrier P, et al: Long-term risk of sarcoma following radiation treatment for breast cancer. Int J Radiat Oncol Biol Phys 21:361-367, 1991
31. Strobbe LJ, Peterse HL, van Tinteren H, et al: Angiosarcoma of the breast after conservation therapy for invasive cancer, the incidence and outcome: An unforeseen sequela. Breast Cancer Res Treat 47:101-109, 1998
32. Neugut AI, Robinson E, Lee WC, et al: Lung cancer after radiation therapy for breast cancer. Cancer 71:3054-3057, 1993
33. Ahsan H, Neugut AI: Radiation therapy for breast cancer and increased risk for esophageal carcinoma. Ann Intern Med 128:114-117, 1998
34. Nixon AJ, Manola J, Gelman R, et al: No long-term increase in cardiac-related mortality after breast-conserving surgery and radiation therapy using modern techniques. J Clin Oncol 16:1374-1379, 1998
35. Gyenes G, Rutqvist LE, Liedberg A, et al: Long-term cardiac morbidity and mortality in a randomized trial of pre- and postoperative radiation therapy versus surgery alone in primary breast cancer. Radiother Oncol 48:185-190, 1998
36. Rutqvist LE, Liedberg A, Hammar N, et al: Myocardial infarction among women with early-stage breast cancer treated with conservative surgery and breast irradiation. Int J Radiat Oncol Biol Phys 40:359-363, 1998
37. Veronesi U, Marubini E, Mariani L, et al: Radiotherapy after breast-conserving surgery in small breast carcinoma: Long-term results of a randomized trial. Ann Oncol 12:997-1003, 2001
38. Wolmark N, Dignam J, Margolese R, et al: The role of radiotherapy and tamoxifen in the management of node negative invasive breast cancer -1.0 cm treated with lumpectomy: Preliminary results of NSABP Protocol B-21. Proc Am Soc Clin Oncol 19:70a, 2000 (abstr 271)
39. Abner AL, Recht A, Eberlein T, et al: Prognosis following salvage mastectomy for recurrence in the breast after conservative surgery and radiation therapy for early-stage breast cancer. J Clin Oncol 11:44-48, 1993
40. Surveillance, Epidemiology, End-Results: SEER Cancer Statistics Review 1973-1998. National Cancer Institute Section 4-Breast, 1973-1998. http://seer.cancer.gov/Publications/CSR1973_1998/breast.pdf
41. Hellman S: Natural history of small breast cancers. J Clin Oncol 12:2229-2234, 1994
42. Recht A: Local control and survival in early stage breast cancer. Breast J 4:372-378, 1998
43. EMMES Corporation: A reanalysis of NSABP protocol B-06. Rockville, MD, National Cancer Institute, CancerNet document: cn-400027, 1994
44. EMMES Corporation: Reanalysis of audited data for NSABP protocol B-06. Rockville, MD, National Cancer Institute, CancerNet document: cn-400043, 1995
45. Liljegren G, Holmberg L, Adami HO, et al: Sector resection with or without postoperative radiotherapy for stage I breast cancer: Five-year results of a randomized trial-Uppsala-Orebro Breast Cancer Study Group. J Natl Cancer Inst 86:717-722, 1994
46. Salvadori B: Local recurrences after breast-conserving treatment: An open problem. Semin Surg Oncol 12:46-52, 1996
47. Renton SC, Gazet JC, Ford HT, et al: The importance of the resection margin in conservative surgery for breast cancer. Eur J Surg Oncol 22:17-22, 1996
48. Whelan T, Clark R, Roberts R, et al: Ipsilateral breast tumor recurrence postlumpectomy is predictive of subsequent mortality: Results from a randomized trial-Investigators of the Ontario Clinical Oncology Group. Int J Radiat Oncol Biol Phys 30:11-16, 1994
49. Hayman JA, Fairclough DL, Harris JR, et al: Patient preferences concerning the trade-off between the risks and benefits of routine radiation therapy after conservative surgery for early-stage breast cancer. J Clin Oncol 15:1252-1260, 1997
50. Palda VA, Llewellyn-Thomas HA, Mackenzie RG, et al: Breast cancer patients' attitudes about rationing postlumpectomy radiation therapy: Applicability of trade-off methods to policy-making. J Clin Oncol 15:3192-3200, 1997