Increased frequency of X-bearing sperm in males from an infertility clinic: Analysis by two-color fluorescence in situ hybridization

Cytogenetic and Genome Research

Volumn 98, Issue 4, 2002, Pages 240-244

  Johannisson, R ^a   Leuschner, E ^a   Huppe M ^a   Hinrichs, F ^a   Al Hasani, S ^a   Diedrich, K ^a   Schwinger, E ^a   Mennicke, K ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FREQUENCY; HEALTH CARE FACILITY; HUMAN; HUMAN CELL; MALE; MALE INFERTILITY; PRIORITY JOURNAL; SEMEN ANALYSIS; SPERM; SPERMATOZOON; STATISTICAL ANALYSIS; X CHROMOSOME; Y CHROMOSOME; CYTOLOGY; GENDER AND SEX; MIDDLE AGED;

ADULT; CHROMOSOMES, HUMAN, X; CHROMOSOMES, HUMAN, Y; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFERTILITY, MALE; MALE; MIDDLE AGED; SEMEN; SEX DETERMINATION (GENETICS); SPERMATOZOA;

EID: 0038148001     PISSN: 14248581     EISSN: None     Source Type: Journal    
DOI: 10.1159/000071041     Document Type: Article

References (36)

1. Asada H, Sueoka K, Hashiba T, Kuroshima M, Kobayashi N, Yoshimura Y: The effects of age and abnormal sperm count on the nondisjunction of spermatozoa. J Assist Reprod Genet 17:51-59 (2000).
2. Bernardini L, Martini E, Geraedts JPM, Hopman AHN, Lanteri S, Conte N, Capitanio GL: Comparison of gonosomal aneuploidy in spermatozoa of normal fertile men and those with severe male factor detected by in-situ hybridization. Mol hum Reprod 3:431-438 (1997).
3. Chevret E, Rousseaux S, Monteil M, Pelletier R, Cozzi J, Sele B: Meiotic segregation of the X and Y chromosomes and chromosome 1 analyzed by three-color FISH in human interphase spermatozoa. Cytogenet Cell Genet 71:126-130 (1995).
4. CIA: The world factbook - sex ratio (http://www. cia.gov/cia/ publications/factbook/fields/sex_ratio. html) (2001).
5. Colls P, Blanco J, Martinez-Pasarell O, Vidal F, Egozcue J, Marquez C, Guitart M, Templado C: Chromosome segregation in a man heterozygous for a pericentric inversion, inv(9)(p11q13), analysed by using sperm karyotyping and two-colour fluorescence in situ hybridization on sperm nuclei. Hum Genet 99:761-765 (1997).
6. Cui KH: Size differences between human X and Y spermatozoa and prefertilization diagnosis. Mol hum Reprod 3:61.67 (1997).
7. Dineen T, Nolan A, Harrington J, Greer A, Kennedy R, Houghton JA: Fluorescence in situ hybridization studies on the sex chromosome constitution of human sperm. Arch Androl 39:217-222 (1997).
8. Downie SE, Flaherty SP, Matthews CD: Detection of chromosomes and estimation of aneuploidy in human spermatozoa using fluorescence in-situ hybidization. Mol hum Reprod 3:585-598 (1997).
9. Finkelstein S, Mukamel E, Yavetz H, Paz G, Avivi L: Increased rate of nondisjunction in sex cells derived from low-quality semen. Hum Genet 102: 129-137 (1998).
10. Griffin DK, Abruzzo MA, Millie EA, Feingold E, Hassold TJ: Sex ratio in normal and disomic sperm: evidence that the extra chromosome 21 preferentially segregates with the Y chromosome. Am J hum Genet 59:1108-1113 (1996).
11. Guttenbach M, Engel W, Schmid M: Analysis of structural and numerical chromosome abnormalities in sperm of normal men and carriers of constitutional chromosome aberrations. A review. Hum Genet 100:1-21 (1997).
12. Hamilton JB: Role of testicular secretions as indicated by effects of castration in man and by studies of pathological conditions and short life span associated with maleness. Recent Progr Hormone Res 3:257-265 (1948).
13. Härkönen K, Suominen J, Lähdetie J: Aneuploidy in spermatozoa of infertile men with teratozoospermia. Int J Androl 24:197-205 (2001).
14. Hilsenrath RE, Swarup M, Bischoff FZ, Buster JE; Carson SA: Effect of sexual abstinence marginally increases the proportion of X-bearing sperm in the ejaculate as assessed by multicolor fluorescent in situ hybridization. Fertil Steril 68:510-513 (1997).
15. Irving J, Bittles A, Peverall J, Murch A, Matson P: The ratio of X- and Y-bearing sperm in ejaculates of men with three or more children of the same sex. J Assist Reprod Genet 16:492-494 (1999).
16. Jacobsen R, Bostofte E, Skakkebaek NE, Hansen J, Moller H: Offspring sex ratio of subfertile men and men with abnormal sperm characteristics. Hum Reprod. 15:2369-2370 (2000).
17. Li P, Hoshiai H: Detection of numerical chromosome abnormalities in human spermatozoa by three-color fluorescence in situ hybridization. J Obstet Gynaecol Res 24:385-392 (1998).
18. Martin RH: Analysis of sperm chromosome complements from a man heterozygous for a pericentric inversion, inv(8)(p23q22). Cytogenet Cell Genet 62:199-202 (1993).
19. Martin RH, Rademaker AW: Reliability of aneuploidy estimates in human sperm: result of fluorescence in situ hybridization studies using two different scoring criteria. Mol Reprod Dev 42:89-93 (1995).
20. Martin RH, Spriggs E, Ko E, Rademaker AW: The relationship between paternal age, sex ratios, and aneuploidy frequencies in human sperm as assessed by multicolor FISH. Am J hum Genet 57:1395-1399 (1995).
21. Martin RH, Spriggs E, Rademaker AW: Multicolor fluorescence in situ hybridization analysis of aneuploidy and diploidy frequencies in 255846 sperm from 10 normal men. Biol Reprod 54:394-398 (1996).
22. Martin RH, Ernst S, Rademaker A, Barclay L, Ko E, Summers N: Chromosomal abnormalities in sperm from testicular cancer patients before and after chemotherapy. Hum Genet 99:214-218 (1997).
23. Martinez-Pasarell O, Marquez C, Coll MD, Egozcue J, Templado C: Analysis of human sperm-derived pronuclei by three-colour fluorescent in-situ hybridization. Hum Reprod 12:641-645 (1997).
24. Martinez-Pasarell O, Nogues C, Bosch M, Egozcue J, Templado C: Analysis of sex chromosome aneuploidy in sperm from fathers of Turner syndrome patients. Hum Genet 104:345-349 (1999).
25. Martini E, Geraedts JPM, Liebaers I, Land JA, Capitanio GL, Ramaekers FCS, Hopman AHN: Constitution of semen samples from XYY and XXY males analysed by in-situ hybridization. Hum Reprod 11:1638-1643 (1996).
26. Mercier S, Bresson JL: Analysis of chromosomal equipment in spermatozoa of a 46,XY/47,XY/+8 male by means of multicolour fluorescent in situ hybridization: confirmation of a mosaicism and evaluation of risk for offspring. Hum Genet 99:42-46 (1997).
27. Moosani N, Pattinson HA, Carter MD, Cox DM, Rademaker AW, Martin RH: Chromosomal analysis of sperm from men with idiopathic infertility using sperm karyotyping and fluorescence in situ hybridization. Fertil Steril 64:811-817 (1995).
28. Morel F, Roux C, Bresson JL: Segregation of sex chromosomes in spermatozoa of 46,XY/47,XXY men by multicolour fluorescence in situ hybridization. Mol Hum Reprod 6:566-570 (2000).
29. Rives N, Mazurier, Bellet D, Joly G, Macé B: Assessment of autosome and gonosome disomy in human sperm nuclei by chromosome painting. Hum Genet 102:616-623 (1998).
30. Rubio C, Gil-Salom M, Simon C, Vidal F, Rodrigo L, Minguez Y, Remohi J, Pellicer A: Incidence of sperm chromosomal abnormalities in a risk population: relationship with sperm quality and ICSI outcome. Hum Reprod 16:2084-2092 (2001).
31. Schultz H, Mennicke K, Schlieker H, Al-Hasani S, Bals-Pratsch M, Diedrich K, Schwinger E: Comparative study of disomy and diploidy rates in spermatozoa of fertile and infertile men: a donor-adapted protocol for multi-colour fluorescence in situ hybridization (FISH). Int J Androl 23:300-308 (2000).
32. Shettles LB: Factors influencing sex ratios. Int J Gynaecol Obst 8:643-647 (1970).
33. Spriggs EL, Rademaker AW, Martin RH: Aneuploidy in human sperm: the use of multicolor FISH to test various theories of nondisjunction. Am J hum Genet 58:356-362 (1996).
34. Templado C, Márquez C, Munné S, Colls P, Martorell MR, Cieply K, Benet J, Van Kirk V, Navarro J, Estop AM: An analysis of human sperm chromosome aneuploidy. Cytogenet Cell Genet 74:194-200 (1996).
35. Templado C, Hoang T, Greene C, Rademaker A, Chernos J, Martin R: Aneuploid spermatozoa in infertile men: teratozoospermia. Mol Reprod Dev 61: 200-204 (2002).
36. Vegetti W, Van Assche E, Frias A, Verheyen G, Bianchi MM, Bonduelle M, Liebaers I, Van Steirteghem: Correlation between semen parameters and sperm aneuploidy rates investigated by fluorescence in-situ hybridization in infertile men. Hum Reprod 15:351-365 (2000).