Sex ratio in normal and disomic sperm: Evidence that the extra chromosome 21 preferentially segregates with the Y chromosome

American Journal of Human Genetics

Volumn 59, Issue 5, 1996, Pages 1108-1113

  Griffin, Darren K ^a   Abruzzo, Michael A ^a   Millie, Elise A ^a   Feingold, Eleanor ^c   Hassold, Terry J ^a,b  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 21; CHROMOSOME SEGREGATION; DISOMY; DOWN SYNDROME; FERTILIZATION; GENETIC SELECTION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; SEX RATIO; SPERMATOGENESIS; SPERMATOZOON ABNORMALITY; SUPERNUMERARY CHROMOSOME; TRISOMY 21; Y CHROMOSOME;

CHROMOSOMES, HUMAN, PAIR 18; CHROMOSOMES, HUMAN, PAIR 21; DOWN SYNDROME; FEMALE; HUMANS; INFANT, NEWBORN; MALE; SEX DETERMINATION (ANALYSIS); SEX RATIO; SPERMATOZOA; X CHROMOSOME; Y CHROMOSOME;

EID: 0029858069     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Chakyo CA, Martin-DeLeon PA (1992) The murine Rb(6.16) translocation: alterations in the proportion of alternate sperm segregants affecting fertilization in vitro and in vivo. Hum Genet 90:79-85
2. Fisher JM, Harvey JF, Morton NE, Jacobs PA (1995) Trisomy 18: studies of the parent and cell division of origin and the effect of aberrant recombination on nondisjunction. Am J Hum Genet 56:669-675
3. Griffin DK, Abruzzo MA, Millie EA, Sheean LA, Feingold E, Sherman SL, Hassold TJ (1995) Non-disjunction in human sperm: evidence for an effect of increasing paternal age. Hum Mol Genet 4:2227-2232
4. Hassold T, Quillen SD, Yamane JA (1983) Sex ratio in spontaneous abortions. Ann Hum Genet 47:39-47
5. Hawley RS, Theurkauf W (1993) Requiem for distributive segregation: achiasmate segregation in Drosophila females. Trends Genet 9:310-317