Effect of lidamycin on the expression of genes involved in invasion regulation in HCT-8 human colon cancer cells

Yaoxue Xuebao

Volumn 36, Issue 4, 2001, Pages 248-249

  Cui, Da Peng ^a   Wang, Zhen ^a   Li, Dian Dong ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

Antitumor antibiotic; cDNA arrays; Lidamycin; Matrix metalloproteinases (MMPs); Tissue inhibitor of metalloproteinases (TIMPs)

Indexed keywords

AMINOGLYCOSIDE; ANTIBIOTIC C 1027; ANTIINFECTIVE AGENT; ANTINEOPLASTIC ANTIBIOTIC; ENEDIYNE; GELATINASE B; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ARTICLE; BIOSYNTHESIS; CANCER INVASION; CELL CULTURE; COLON TUMOR; DRUG EFFECT; GENE EXPRESSION; GENETICS; HUMAN; PATHOLOGY;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTINEOPLASTIC; COLONIC NEOPLASMS; ENEDIYNES; GENE EXPRESSION; HUMANS; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TUMOR CELLS, CULTURED;

EID: 0038142836     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Hu JL, Xue YC, Xie MY, et al. A new macromolecular antitumor antibiotic, C-1027. I. Discovery, taxonomy of producing organism, fermentation and biological activity [J]. J Antibiot, 1988, 41(11): 1575-1579.
2. Xu YJ, Xi Z, Zhen YS, et al. Mechanism of formation of novel covalent drug. DNA interstrand cross-links and monoadducts by enediyne antitumor antibiotics [J]. Biochemistry, 1997, 36(48): 14975-14984.
3. Zhen YS, Ming XY, Yu B, et al. A new macromolecular antitumor antibiotic, C-1027. III. Antitumor activity [J]. J Antibiot, 1989, 42(8): 1294-1298.
4. Zhen HY, Xue YC, Zhen YS. Inhibition of angiogenesis by antitumor antibiotic C1027 and its effect on tumor metastasis [J]. Natl Med J China (in Chinese), 1997, 77(9): 657-660.
5. Stetler-Stevenson WG, Aznavoorian S, Litta LA. Tumor cell interactions with extracellular matrix during invasion and metastasis [J]. Annu Rev Cell Biol, 1993, 9: 541-573.
6. Gomez DE, Alonso DF, Yoshiji H. Tissue inhibitors of metalloproteinases: structure, regulation and biological functions [J]. Eur J Cell Biol, 1997, 74 (2): 111-122.
7. Sambrook J, Fritsch EF, Moniatis T. (Yu MX translator). Molecular Cloning. A laboratory Manual [M]. Beijing: Science Press, 1992.362-364.
8. Dieffenbanch CW, Dvekslex GS. (Huang PT translator). PCR Primer. A laboratory Manual [M]. Beijing: Science Press, 1998. 205-208.
9. Woodhouse EC, Chuaqui RF, Litta LA. General mechanism of metastasis [J]. Cancer, 1997, 80 (8 Suppl): 1529-1537.
10. Liotta LA, Tryggvason K, Carbissa S, et al. Metastatic potential correlates with enzymatic degradation of basement membrane collagen [J]. Nature, 1980, 284 (5751): 67-68.
11. Sawaya RE, Yamamoto M, Gokaslan ZL, et al. Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo [J]. Clin Exp Metastasis , 1996, 14(1): 35-42.
12. Graham CH, Connelly I, Macdougall JR. Resistance of malignant trophoblast cells to both the anti-proliferative and anti-invasive effects of transforming growth factor-beta [J]. Exp Cell Res, 1994, 214(1): 93-99.
13. Kawamata H, Kawai K, Kameyama S, et al. Overexpression of tissue inhibitor of matrix metalloproteinases (TIMP-1 and TIMP-2) suppresses extravasation of pulmonary metastasis of a rat bladder carcinoma [J]. Int J Cancer , 1995, 63(5): 680-687.
14. Apte SS, Olsen BR, Murphy G. The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family [J]. J Biol Chem, 1995, 270(24): 14313-14318.
15. Derisi JL, Penland L, Brown PO, et al. Use of cDNA microarrays to analyse gene expression patterns in human cancer [J]. Nat Genet , 1996, 14(4): 457-460.