Role of copper in the relaxant action of S-nitrosothiols in the rat anococcygeus muscle

Clinical and Experimental Pharmacology and Physiology

Volumn 30, Issue 5-6, 2003, Pages 357-361

  Ng, Chi Wai ^a   Najbar Kaszkiel, Alicja T ^a   Li, Chun Guang ^a  

^a RMIT UNIVERSITY   (Australia)

Author keywords

Anococcygeus muscle (rat); Copper; Copper chelators; Cuprizone; Neocuproine; Nitric oxide; S nitrosothiols

Indexed keywords

2,9 DIMETHYL 1,10 PHENANTHROLINE; CHELATING AGENT; CLONIDINE; COPPER; CUPRIZONE; GUANETHIDINE; N ACETYLPENICILLAMINE; NITRIC OXIDE; S NITROSOGLUTATHIONE; S NITROSOTHIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOCOCCYGEUS MUSCLE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DECOMPOSITION; DRUG EFFECT; ELECTRIC FIELD; ELECTROSTIMULATION; MALE; MUSCLE RELAXATION; NERVE STIMULATION; NEUROTRANSMITTER RELEASE; NONHUMAN; OXIDATION REDUCTION REACTION; RAT; VASCULAR SMOOTH MUSCLE;

ANAL CANAL; ANIMALS; CHELATING AGENTS; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MUSCLE RELAXATION; NITRERGIC NEURONS; RATS; RATS, SPRAGUE-DAWLEY; S-NITROSOTHIOLS; SACROCOCCYGEAL REGION;

EID: 0038132923     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2003.03845.x     Document Type: Article

References (22)

1. Williams DL. S-Nitrosothiols and role of metal ions in decomposition of nitric oxide. Methods Enzymol. 1996; 268: 299-308.
2. Jourd'heuil D, Laroux FS, Kang D, Miles AM, Wink DA, Grisham MB. Stability of S-nitrosothiols in presence of copper, zinc-superoxide dismutase. Methods Enzymol. 1999; 310: 220-7.
3. Butler AR, Rhodes P. Chemistry, analysis, and biological roles of S-nitrosothiols. Anal. Biochem. 1997; 249: 1-9.
4. Gordge MP, Meyer DJ, Hothersall J, Neild GH, Payne NN, Noronha-Dutra A. Copper chelation-induced reduction of the biological activity of S-nitrosothiols. Br. J. Pharmacol. 1995; 114: 1083-9.
5. 2+ on relaxations to the nitrergic neurotransmitter, NO and S-nitrosothiols in the rat gastric fundus. Br. J. Pharmacol. 1996; 119: 990-6.
6. 2+ sources. Chem. Biol. 1996; 3: 655-9.
7. Al-Sa'Doni HH, Megson IL, Bisland S, Butler AR, Flitney FW. Neocuproine, a selective Cu[I] chelator, and the relaxation of rat vascular smooth muscle by S-nitrosothiols. Br. J. Pharmacol. 1997; 121: 1047-50.
8. Ng CW, Li CG, Najbar-Kaszkiel AT. The effect of copper chelators on relaxations induced by S-nitrosothiols and the nitrergic neurotransminer. Proc. Australas. Soc. Clin. Exp. Pharmacol. Toxicol. 1999; 6: 47 (Abstract).
9. Li CG, Rand MJ. Evidence for a role of nitric oxide in the neurotransmitter system mediating relaxation of the rat anococcygeus muscle. Clin. Exp. Pharmacol. Physiol. 1989; 16: 933-8.
10. Gillespie JS. The rat anococcygeus muscle and its response to nerve stimulation and to some drugs. Br. J. Pharmacol. 1972; 45: 404-16.
11. Feelisch M. The biochemical pathways nitric oxide formation from nitrovasodilators. Appropriate choice of exogenous NO donors and aspects of preparation and handling of aqueous NO solutions. J. Cardiovasc. Pharmacol. 1991; 17 (Suppl.): S25-33.
12. Gorren AC, Schrammel A, Schmidt K, Mayer B. Decomposition of S-nitrosoglutathione in the presence of copper ions and glutathione. Arch. Biochem. Biophys. 1996; 330: 219-28.
13. De Man JG, Moreels TG, De Winter BY, Herman AG, Pelckmans PA. Neocuproine potentiates the activity of the nitrergic neurotransmitter but inhibits that of S-nitrosothiols. Eur. J. Pharmacol. 1999; 381: 151-9.
14. Rand MJ, Li CG. Differential effects of hydroxocobalamin on relaxations induced by nitrosothiols in rat aorta and anococcygues muscle. Eur. J. Pharmacol. 1993; 241: 249-54.
15. De Man JG, Boeckxstaens GE, De Winter BY et al. Comparison of the pharmacological profile of S-nitrosothiols, nitric oxide and the nitrergic neurotransmitter in the canine ileocolonic junction. Br. J. Pharmacol. 1995; 114: 1179-84.
16. Barbier AJ, Lefebvre RA. Influence of S-nitrosothiols and nitrate tolerance in the rat gastric fundus. Br. J. Pharmacol. 1994; 111: 1280-6.
17. Gibson A, Babbedge R, Brave SR et al. An investigation of some S-nitrosothiols, and of hydroxy-arginine, on the mouse anococcygeus. Br. J. Pharmacol. 1992; 107: 715-21.
18. Garcia-Pascual A, Costa G, Labadia A, Jimenez E, Triguero D. Differential mechanisms of urethral smooth muscle relaxation by several NO donors and nitric oxide. Naunyn Schmiedebergs Arch. Pharmacol. 1999; 360: 80-91.
19. Mathews WR, Kerr SW. Biological activity of S-nitrosothiols: The role of nitric oxide. J. Pharmacol. Exp. Ther. 1993; 267: 1529-37.
20. Van Der Zypp A, Majewski H. Effect of cGMP inhibitors on the actions of nitrodilators in rat aorta. Clin. Exp. Pharmacol. Physiol. 1998; 25: 38-43.
21. Pfeiffer S, Schrammel A, Schmidt K, Mayer B. Electrochemical determination of S-nitrosothiols with Clark-type nitric oxide electrode. Anal. Biochem. 1998; 258: 68-73.
22. Li CG, Karagiannis J, Rand MJ. Comparison of the redox forms of nitrogen monoxide with the nitrergic transmitter in the rat anococcygeus muscle. Br. J. Pharmacol. 1999; 127: 826-34.