Effect of cGMP inhibitors on the actions of nitrodilators in rat aorta

Clinical and Experimental Pharmacology and Physiology

Volumn 25, Issue 1, 1998, Pages 38-43

  Van Der Zypp, Andrea ^a   Majewski, Henryk ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

cGMP; Glyceryltrinitrate; KT 5823; Nitric oxide; ODQ; Protein kinase G; R(p) 8 bromoguanosine cyclic monophosphothioate; SNAP; Sodium nitroprusside; Vacular smooth muscle

Indexed keywords

ACETYLCHOLINE; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; GLYCERYL TRINITRATE; GUANYLATE CYCLASE; GUANYLATE CYCLASE INHIBITOR; KT 5823; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; MALE; NONHUMAN; RAT; SMOOTH MUSCLE RELAXATION; VASCULAR RING; VASCULAR SMOOTH MUSCLE; VASODILATATION;

EID: 0031884780     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1998.tb02141.x     Document Type: Article

References (35)

1. Holzmann S. Endothelium-induced relaxation by acetylcholine associated with larger rises in cyclic GMP in coronary arterial strips. J. Cyclic Nucleotide Res. 1982; 8: 409-19.
2. Rapoport RM, Murad F. Agonist-induced endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP. Circ. Res. 1983; 52: 352-7.
3. 2+ by sarcoplasmic reticulum in vascular smooth muscle. Circ. Res. 1988; 62: 961-4.
4. Taylor CJ, Meisheri KD. Inhibitory effects of a synthetic atrial peptide on contractions and 45Ca fluxes in vascular smooth muscle. J. Pharmacol. Exp. Ther. 1986; 237: 803-8.
5. 2+ pump by cyclic nucleotides in cultured vascular smooth muscle cells. J. Biol. Chem. 1988; 263: 8058-65.
6. Ito Y, Suzuki H, Kuriyama H. Effects of sodium nitroprusside on smooth muscle cells of rabbit pulmonary artery and portal vein. J. Pharmacol. Exp. Ther. 1978; 207: 1022-31.
7. Pfitzer G, Merkel L, Ruegg JC, Hofmann F. Cyclic GMP-dependent protein kinase relaxes skinned fibres from guinea pig taenia coli but not from chicken gizzard. Pflügers Arch. 1986; 407: 87-91.
8. i, myosin light chain phosphorylation, and contraction in human myometrium. Am. J. Physiol. 1991; 260: C861-7.
9. Böhme E, Graf H. Schultz G. Effects of sodium nitroprusside and other smooth muscle relaxants on cyclic GMP formation in smooth muscle and platelets. Adv. Cycl. Nucl. Res. 1978; 9: 131-43.
10. Kobayashi A, Suzuki Y, Kamikawa T, Hayashi H, Yamazaki W. The effect of nitroglycerin on cyclic nucleotides in the coronary artery in vivo. Life Sci. 1980; 27: 1679-85.
11. Murad F. Cyclic guanosine monophosphate as a mediator of vasodilatation. J. Clin. Invest. 1986; 78: 1-5.
12. Kiedrowski L, Manev H, Costa E, Wroblewski JT. Inhibition of glutamate-induced cell death by sodium nitroprusside is not mediated by nitric oxide. Neuroscience 1991; 30: 1241-3.
13. Yu, Chuang DM. Inhibition of excitatory amino acid-induced phosphoinositide hydrolysis as a possible mechanism of nitroprusside neurotoxicity. J. Neurochem. 1996; 66: 346-54.
14. Brown JF, Hanson PJ, Whittle BJR. The nitric oxide donor, S-nitrosoacetylpenicillamine, inhibits secretory activity in rat isolated parietal cells. Biochem. Biophys. Res. Commun. 1993; 195: 1354-9.
15. Noack E, Feelisch M. Molecular mechanism of nitrovasodilator bioactivation. Basic Res. Cardiol. 1991; 86 (Suppl. 2): 37-50.
16. Kowaluk A, Seth P, Fung H-L. Metabolic activation of sodium nitroprusside to nitric oxide in vascular smooth muscle. J. Pharmacol. Exp. Ther. 1992; 262: 916-22.
17. Harrison DG, Bates JN. The nitrovasodilators. New ideas about old drugs. Circulation 1993; 87: 1461-7.
18. Kase H, Iwahashi K, Nakanishi S et al. K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem. Biophys. Res. Commun. 1987; 142: 436-40.
19. Kase H. New inhibitors of protein kinases from microbial sources. In: Okami Y, Beppu T, Ogawara H (eds). Biology of Actinomycetes 88. Proceedings of the Seventh International Symposium on Biology of Actinomycetes. Japan Scientific Societies Press, Tokyo. 1988; 159-64.
20. Jin J-G, Murthy KS, Grider JR. Makhlouf GM. Activation of distinct-and cGMP-dependent pathways by relaxant agents in isolated gastric muscle cells. Am. J. Physiol. 1993; 264: G470-7.
21. Wahler GM, Dollinger SJ. Nitric oxide donor SIN-1 inhibits mammalian cardiac calcium currents through cGMP-dependent protein kinase. Am. J. Physiol. 1995; 268: C45-54.
22. Wyatt TA, Pryzwansky KB, Lincoln TM. KT 5823 activates human neutrophils and fails to inhibit cGMP-dependent protein kinase phosphorylation of vimentin. Res. Commun. Chem. Path. Pharmacol. 1991; 74: 3-14.
23. Butt E, Van Bemmelen M, Fischer I, Walter U, Jastorff B. Inhibition of cGMP-dependent protein kinase by (Rp)-guanosine 3′,5′-monophosphorothioates. FEBS Lett. 1990; 263: 47-50.
24. Nakazawa M, Imai S. Rp-8-Br-guanosine-3′,5′-cyclic monophosphorothioate inhibits relaxation elicited by nitroglycerin in rabbit aorta. Eur. J. Pharmacol. 1994; 253: 179-81.
25. Zimmerman AL, Yamanaka G, Eckstein F, Baylor DA, Stryer L. Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments. Proc. Natl Acad. Sci. USA 1985; 82: 8813-17.
26. Garthwaite J, Southam E, Boulton CL, Nielsen EB, Schmidt K, Mayer B. Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol. Pharmacol. 1995; 48: 184-8.
27. Lincoln TM, Thompson M, Cornwell TL. Purification and characterization of two isoforms of cyclic GMP-dependent protein kinase from bovine aorta. J. Biol. Chem. 1988; 263: 17 632-7.
28. Wolfe L, Corbin JD, Francis SH. Characterization of a novel isozyme of cyclic GMP-dependent protein kinase from bovine aorta. J. Biol. Chem. 1989; 264: 7734-41.
29. Sekhar KR, Hatchett RJ, Shabb JB et al. Relaxation of pig coronary arteries by new and potent cyclic GMP analogs that selectively activate type 1α, compared with 1γ, cyclic GMP-dependent protein kinase. Mol. Pharmacol. 1992; 42: 103-8.
30. Furchgott RF, Zawadzki JV. The obligatory role of the endothelial cells in relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 288: 373-6.
31. Butler AR, Flitney FW, Williams DLH. NO, nitrosium ions, nitroxide ions, nitrosothiols and iron-nitrosyls in biology: A chemists' perspective. Trends Pharmacol. Sci. 1995; 16: 18-22.
32. Warner TD, Mitchell JA, Sheng H, Murad F. Effects of cyclic GMP on smooth muscle relaxation. Adv. Pharmacol. 1994; 26: 171-94.
33. Kawada T, Ishibashi T, Sasage H, Kato K, Imai S. Modification by LY 83583 and methylene blue of relaxation induced by nitric oxide, glyceryl trinitrate, sodium nitroprusside and atriopeptin in aortae of the rat, guinea-pig and rabbit. Gen. Pharmacol. 1994; 25: 1361-71.
34. Zhou H-L, Torphy TJ. Relationship between cyclic guanosine monophosphate accumulation and relaxation of canine trachealis induced by nitrovasodilators. J. Pharmacol. Exp. Ther. 1991; 258: 972-8.
35. Bozinovski JJ, Brien JF, Marks GS, Nakatsu K. Inhibition of nitrovasodilators by pyocyanin and methylene blue is dissociated from NO formation. Can. J. Physiol. Pharmacol. 1994; 72: 746-52.