Systemic inflammatory responses in children with acute otitis media due to Streptococcus pneumoniae and the impact of treatment with clarithromycin

Clinical and Diagnostic Laboratory Immunology

Volumn 10, Issue 4, 2003, Pages 721-724

  Scharer, Gunter ^a   Zaldivar, Frank ^a   Gonzalez, Guillermo ^a   Vargas Shiraishi, Ofelia ^a   Singh, Jasjit ^a   Arrieta, Antonio ^a  

^a CHILDREN S HOSPITAL OF ORANGE COUNTY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLARITHROMYCIN; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ANTIBIOTIC THERAPY; ARTICLE; BACTERIUM CULTURE; CHILD; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; FOLLOW UP; HUMAN; INFLAMMATION; OTITIS MEDIA; OTOSCOPY; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE; SYMPTOMATOLOGY; TREATMENT PLANNING;

BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD, PRESCHOOL; CLARITHROMYCIN; FOLLOW-UP STUDIES; HUMANS; INFANT; INFLAMMATION; INTERLEUKIN-1; INTERLEUKIN-6; INTERLEUKIN-8; INTERLEUKINS; OTITIS MEDIA WITH EFFUSION; PILOT PROJECTS; PNEUMOCOCCAL INFECTIONS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0038105393     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/CDLI.10.4.721-724.2003     Document Type: Article

References (14)

1. Aderka, D., J. M. Le, and J. Vilcek. 1989. IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice. J. Immunol. 143:3517-3523.
2. Baggiolini, M., A. Walz, and S. L. Kunkel. 1989. Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J. Clin. Investig. 84:1045-1049.
3. Bluestone, C. D. 1989. Modern management of otitis media. Pediatr. Clin. North Am. 36:1371-1387.
4. Chonmaitree,T., M. J. Owen, J. A. Patel, D. Hedgpeth, D. Horlick, and V. M. Howie. 1992. Effect of viral respiratory tract infection on outcome of acute otitis media. J. Pediatr. 120:856-862.
5. Dagan, R., E. Leibovitz, D. Greenberg, P. Yagupsky, D. M. Fliss, and A. Leiberman. 1998. Early eradication of pathogens from middle ear fluid during antibiotic treatment of acute otitis media is associated with improved clinical outcome. Pediatr. Infect. Dis. J. 17:776-782.
6. Freid, V. M., D. M. Mukuc, and R. N. Rooks. 1998. Ambulatory health care visits by children: principal diagnosis and place of visit. Vital Health Stat. 13:1-23.
7. Gates, G. A. 1996. Cost-effectiveness considerations in otitis media treatment. Otolaryngol. Head Neck Surg. 114:525-530.
8. Heikkinen, T., F. Ghaffar, A. O. Okorodudu, and T. Chonmaitree. 1998. Serum interleukin-6 in bacterial and nonbacterial acute otitis media. Pediatrics 102:296-299.
9. Nassif, P. S., S. Q. Simpson, A. A. Izzo, and P. J. Nicklaus. 1998. Epidermal growth factor and transforming growth factor-alpha in middle ear effusion. Otolaryngol. Head Neck Surg. 119:564-568.
10. Pichichero, M. E., and C. L. Pichichero. 1995. Persistent acute otitis media. I. Causative pathogens. Pediatr. Infect. Dis. J. 14:178-183.
11. Roark, R., and S. Berman. 1997. Continuous twice daily or once daily amoxicillin prophylaxis compared with placebo for children with recurrent acute otitis media. Pediatr. Infect. Dis. J. 16:376-381.
12. Schappert, S. M. 1992. Office visits for otitis media: United States, 1975-1990. Adv. Data Vital Health Stat. 214:1-20.
13. Wald, E. R., E. O. Mason, Jr., J. S. Bradley, W. J. Barson, and S. L. Kaplan. 2001. Acute otitis media caused by Streptococcus pneumoniae in children's hospitals between 1994 and 1997. Pediatr. Infect. Dis. J. 20:34-39.
14. Yellon, R. F., W. J. Doyle, T. L. Whiteside, W. F. Diven, A. R. March, and P. Fireman. 1995. Cytokines, immunoglobulins, and bacterial pathogens in middle ear effusions. Arch. Otolaryngol. Head Neck Surg. 121:865-869.