Prenatal elevation of endocannabinois corrects the unbalance between dopamine systems and reduces activity in the Naples High Excitability rats

Neuroscience and Biobehavioral Reviews

Volumn 27, Issue 1-2, 2003, Pages 129-139

  Viggiano, D ^a   Ruocco, L A ^a   Pignatelli, M ^a   Grammatikopoulos, G ^a   Sadile, A G ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

ADHD; AM 404; Animal models; Cytochrome oxydase; Dopamine; Endocannabinoid reuptake blocker; Image analysis; Thyrosine hydroxylase

Indexed keywords

ANANDAMIDE; BIOLOGICAL MARKER; CANNABINOID DERIVATIVE; CYTOCHROME C OXIDASE; DOPAMINE; N (4 HYDROXYPHENYL)ARACHIDONAMIDE; TYROSINE 3 MONOOXYGENASE; ARACHIDONIC ACID DERIVATIVE; CANNABINOID; ENDOCANNABINOID; N (4 HYDROXYPHENYL)ARACHIDONYLAMIDE; N-(4-HYDROXYPHENYL)ARACHIDONYLAMIDE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TESTING ALTERNATIVE; ANIMAL TISSUE; ATTENTION; ATTENTION DEFICIT DISORDER; BRAIN CORTEX; BRAIN DEVELOPMENT; BREED; CONFERENCE PAPER; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC SYSTEM; DRUG EFFECT; FEMALE; GESTATION PERIOD; IMAGE ANALYSIS; MALE; MAZE TEST; METABOLISM; MORPHOMETRICS; NONHUMAN; OPTICAL DENSITY; PRENATAL PERIOD; PRIORITY JOURNAL; PROGENY; RANDOMIZATION; RAT; REARING; SUBSTANTIA NIGRA; VIDEOTAPE; ANIMAL; ARTICLE; BRAIN; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DISEASE MODEL; EMOTION; IMAGE PROCESSING; IMMUNOHISTOCHEMISTRY; METHODOLOGY; MOTOR ACTIVITY; MOVEMENT (PHYSIOLOGY); PATHOLOGY; PATHOPHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE; RAT STRAIN; TIME;

ANIMALS; ARACHIDONIC ACIDS; ATTENTION; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BEHAVIOR, ANIMAL; BRAIN; CANNABINOIDS; DISEASE MODELS, ANIMAL; DOPAMINE; EMOTIONS; ENDOCANNABINOIDS; FEMALE; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; MALE; MOTOR ACTIVITY; MOVEMENT; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, INBRED STRAINS; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 0038069292     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0149-7634(03)00015-0     Document Type: Conference Paper

References (66)

1. Diagnostic and statistical manual of mental health. 4th ed. 1994;American Psychiatric Association, Washington, DC.
2. Armitage P. Statistical methods in medical research. 1980;Blackwell Scientific Publications, Oxford, UK.
3. Aspide R., Fresiello A., De Filippis G., Gironi Carnevale U.A., Sadile A.G. Nonselective attention in a rat model of hyperactivity and attention deficit: subchronic methylphenidate and nitric oxide synthesis inhibitor treatment. Neurosci Biobehav Rev. 24:2000;59-71.
4. Aspide R., Gironi Carnevale U.A., Sergeant J.A., Sergeant A.G. Non-selective attention and nitric oxide in putative animal models of attention-deficit hyperactivity disorder. Behav Brain Res. 95:1998;123-133.
5. 2-receptor responses by an anandamide trasport inhibitor. J Neurosci. 20:2000;3401-3407.
6. Beltramo M., Stella N., Calignano A., Lin S.Y., Makriyannis A., Piomelli D. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. Science. 277:1997;1094-1097.
7. Berger A., Posner M.I. Pathologies of brain attentional networks. Neurosci Biobehav Rev. 24:2000;3-6.
8. Berrendero F., Sepe N., Ramos J.A., Di M., Fernandez R. Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period. Synapse. 33:1999;181-191.
9. Broadhurst P.L. Experiments in psychogenetics: application of biometrical genetics to the inheritance of behavior. Eysenck H.J. Psychogenetics and psychopharmacology. Psychogenetics and psychopharmacology. vol. 1:1960;1-102 Routledge, Regan Paul, London.
10. Buzsaki G. The thalamic clock: emergent network properties. Neuroscience. 41:1991;351-364.
11. Calignano A., La Rana G., Beltramo M., Makriyannis A., Piomelli D. Potentiation of anandamide hypotension by the transport inhibitor, AM-404. Eur J Pharmacol. 337:1997;R1-R2.
12. Capowski J.J. Computer techniques in neuroanatomy. 1989;Plenium Press, New York.
13. Cerbone A., Pellicano M.P., Sadile A.G. Evidence for and against the Naples high- and low-excitability rats as genetic model to study hippocampal functions. Neurosci Biobehav Rev. 17:1993;295-304.
14. Crusio W.E., Schwegler H., Brust I., van Abeelen J.H. Genetic selection for novelty-induced rearing behavior in mice produces changes in hippocampal mossy fiber distributions. J Neurogenet. 5:1989;87-93.
15. Crusio W.E., Schwegler H., van Abeelen J.H. Behavioral responses to novelty and structural variation of the hippocampus in mice. I. Quantitative-genetic analysis of behavior in the open-field. Behav Brain Res. 32:1989;75-80.
16. Di Tomaso E., Cadas H., Gaillet S., Beltramo M., Desarnaud F., Venance L., Piomelli D. Endogenous lipids that activate cannabinoid receptors. Formation and inactivation. Adv Exp Med Biol. 407:1997;335-340.
17. Fernandez R., Berrendero F., Hernandez M.L., Ramos J.A. The endogenous cannabinoid system and brain development. Trends Neurosci. 23:2000;14-20.
18. Gallo A., Gonzalez-Lima F., Sadile A. Impaired metabolic capacity in the perirhinal and posterior parietal cortex lead to dissociation between attentional, motivational and spatial components of exploration in the Naples high excitability rat line. Behav Brain Res. 130:2002;133-140.
19. Garcia-Gil L., Ramos J.A., Rubino T., Parolaro D., Fernandez-Ruiz J.J. Perinatal delta9-tetrahydrocannabinol exposure did not alter dopamine transporter and tyrosine hydroxylase mRNA levels in midbrain dopaminergic neurons of adult male and female rats. Neurotoxicol Teratol. 20:1998;549-553.
20. Gentsch C., Lichtensteiner M., Feer H. Locomotor activity, defecation score and corticosterone levels during an open-field exposure: a comparison among individually and group-housed rats, and genetically selected rat lines. Physiol Behav. 27:1981;183-186.
21. Giuffrida A., Rodriguez D.F., Nava F., Loubet-Lescoulie P., Piomelli D. Elevated circulating levels of anandamide after administration of the transport inhibitor, AM-404. Eur J Pharmacol. 408:2000;161-168.
22. Goldschmidt L., Day N.L., Richardson G.A. Effects of prenatal marijuana exposure on child behavior problems at age 10. Neurotoxicol Teratol. 22:2000;325-336.
23. Gonzalez-Lima F., Jones D. Quantitative mapping of cytochrome oxidase activity in the central nervous system of the gerbil: a study with calibrated activity standards and metal-intensified histochemistry. Brain Res. 660:1994;34-49.
24. Gorriti M.A., Rodriguez D., Navarro M., Palomo T. Chronic (-)-delta9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats. Eur J Pharmacol. 365:1999;133-142.
25. Hendley E.D. WKHA rat with genetic hyperactivity and hyperreactivity to stress: a review. Neurosci Biobehav Rev. 24:2000;41-44.
26. Herkenham M., Lynn A.B., Little M.D., Johnson M.R., Melvin L.S., de C., Rice K.C. Cannabinoid receptor localization in brain. Proc Natl Acad Sci USA. 87:1990;1932-1936.
27. Hillard C.J., Edgemond W.S., Jarrahian A., Campbell W.B. Accumulation of N-arachidonoylethanolamine (anandamide) into cerebellar granule cells occurs via facilitated diffusion. J Neurochem. 69:1997;631-638.
28. Kalaria R.N., Bhatti S.U., Lust W.D., Perry G. The amyloid precursor protein in ischemic brain injury and chronic hypoperfusion. Ann NY Acad Sci. 695:1993;190-193.
29. Ledent C., Valverde O., Cossu G., Petitet F., Aubert J.F., Beslot F., Bohme G.A., Imperato A., Pedrazzini T., Roques B.P., Vassart G., Fratta W., Parmentier M. Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science. 283:1999;401-404.
30. LeDoux J.E., Muller J. Emotional memory and psychopathology. Philos Trans R Soc Lond B Biol Sci. 352:1997;1719-1726.
31. Levitt P., Harvey J.A., Friedman E., Simansky K., Murphy E.H. New evidence for neurotransmitter influences on brain development. Trends Neurosci. 20:1997;269-274.
32. Mailleux P., Vanderhaeghen J.J. Localization of cannabinoid receptor in the human developing and adult basal ganglia. Higher levels in the striatonigral neurons. Neurosci Lett. 148:1992;173-176.
33. Marrocco R.T., Witte E.A., Davidson M.C. Arousal systems. Curr Opin Neurobiol. 4:1994;166-170.
34. Matsuda L.A., Bonner T.I., Lolait S.J. Localization of cannabinoid receptor mRNA in rat brain. J Comp Neurol. 327:1993;535-550.
35. Mirochnick M., Meyer J., Frank D.A., Cabral H., Tronick E.Z., Zuckerman B. Elevated plasma norepinephrine after in utero exposure to cocaine and marijuana. Pediatrics. 99:1997;555-559.
36. Moruzzi G., Magoun H.W. Brain stem reticular formation and activation of EEG. Electroencephalogr Clin Neurophysiol. 1:1949;455-473.
37. Navarro M., Rodriguez D.F., Hernandez M.L., Ramos J.A., Fernandez-Ruiz J.J. Motor behavior and nigrostriatal dopaminergic activity in adult rats perinatally exposed to cannabinoids. Pharmacol Biochem Behav. 47:1994;47-58.
38. Noisin E.L., Thomas W.E. Ontogeny of dopaminergic function in the rat midbrain tegmentum, corpus striatum and frontal cortex. Brain Res. 469:1988;241-252.
39. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 1986;Academic Press, London.
40. Pellicano M.P., Sadile A.G. An autoradiographic study of 3H-L-glutamate binding sites in the brain of the Naples High Excitability rats. Neurosci Lett. supp 43:1992;S86.
41. Pellicano M.P., Siciliano F., Sadile A.G. NMDA receptors modulate behavioral plasticity as assessed by dose and genotype-dependent differential effects of post-trial MK-801 and CPP on long-term habituation to spatial novelty in rats. Physiol Behav. 54:1993;563-568.
42. Perrone-Capano C., di Porzio U. Genetic and epigenetic control of midbrain dopaminergic neuron development. Int J Dev Biol. 44:2000;679-687.
43. Pertwee R.G. Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacol Ther. 74:1997;129-180.
44. Piomelli D., Beltramo M., Glasnapp S., Lin S.Y., Goutopoulos A., Xie X.Q., Makriyannis A. Structural determinants for recognition and translocation by the anandamide transporter. Proc Natl Acad Sci USA. 96:1999;5802-5807.
45. Posner M.I., Dehasne S. Attentional networks. Trends Neurosci. 17:1994;75-79.
46. Pryor G.T., Larsen F.F., Husain S., Braude M.C. Interactions of delta9-tetrahydrocannabinol with d-amphetamine, cocaine, and nicotine in rats. Pharmacol Biochem Behav. 8:1978;295-318.
47. Robbins T.W., Everitt B.J. Arousal systems and attention. Gazzaniga M.S. The cognitive neurosciences. 1994;703-720 MIT Press, Cambridge, MA.
48. Rodriguez D.F., Cebeira M., Fernandez-Ruiz J.J., Navarro M., Ramos J.A. Effects of pre- and perinatal exposure to hashish extracts on the ontogeny of brain dopaminergic neurons. Neuroscience. 43:1991;713-723.
49. Sagvolden T. Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of attention-deficit hyperactivity disorder (AD/HD). Neurosci Biobehav Rev. 24:2000;31-40.
50. Sagvolden T., Hendley E.D., Knardahl S. Behavior of hypertensive and hyperactive rat strains: hyperactivity is not unitarily determined. Physiol Behav. 52:1992;49-57.
51. Sagvolden T., Pettersen M.B., Larsen M.C. Spontaneously hypertensive rats (SHR) as a putative animal model of childhood hyperkinesis: SHR behavior compared to four other rat strains. Physiol Behav. 54:1993;1047-1055.
52. Sanders D.C. The Bethlem lines: genetic selection for high and low rearing activity in rats. Behav Genet. 11:1981;491-503.
53. Specht L.A., Pickel V.M., Joh T.H., Reis D.J. Light-microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. I. Early ontogeny. J Comp Neurol. 199:1981;233-253.
54. Steriade M. Synchronised activities of coupled oscillators in the cerebral cortex and thalamus at different levels of vigilance. Cereb Cortex. 7:1997;583-604.
55. Swanson J.M., Sergeant J.A., Taylor E., Sonuga-Barke E.J.S., Jensen P.S., Cantwell D.P. Attention deficit hyperactivity disorder and hyperkinetic disorder. Lancet. 351:1998;329-343.
56. Thiel C.M., Muller C.P., Huston J.P., Schwarting R.K. High versus low reactivity to a novel environment: behavioural, pharmacological and neurochemical assessments. Neuroscience. 93:1999;243-251.
57. Tsou K., Brown S., Sanudo P., Mackie K., Walker J.M. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience. 83:1998;393-411.
58. Vallone D., Pignatelli M., Grammatikopoulus G., Rocco L., Bozzi Y., Westphal H., Borrelli E., Sadile A. Activity, non-selective attention and emotionally in dopamine D-2/D-3 receptor knock out mice. Behav Brain Res. 130:2002;141-148.
59. Vallone D., Viggiano D., Sadile A.G. A hyperfunctioning mesocortical system in the Naples high excitability rats as assessed by morphometry and molecular biology studies. Soc Neurosci. 28:2003;. Abstract.
60. van Abeelen J.H.F. Genetics of rearing behavior in mice. Behav Genet. vol. 1:1970;71-76.
61. van Abeelen J.H.F. Genetic analysis of behavioral responses to novelty in mice. Nature. 254:1975;239-241.
62. Viggiano D., Grammatikopoulos G., Sadile A.G. A morphometric evidence for a hyperfunctioning mesolimbic system in an animal model of ADHD. Behav Brain Res. 130:2002;181-189.
63. Viggiano D., Sadile A.G. Hypertrophic A10 dopamine neurons in a rat model of attention-deficit hyperactivity disorder (ADHD). Neuroreport. 11:2000;3677-3680.
64. Viggiano D., Vallone D., Welzl H., Sadile A.G. The Naples high- and low excitability rats: selective breeding, behavioral profile, brain morphometry, and molecular biology of the mesocortical dopamine system. Behav Genet. 32:2002;315-333.
65. Zimmer A., Zimmer A.M., Hohmann A.G., Herkenham M., Bonner T.I. Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc Natl Acad Sci USA. 96:1999;5780-5785.
66. Zygmunt P.M., Chuang H., Movahed P., Julius D., Hogestatt E.D. The anandamide transport inhibitor AM-404 activates vanilloid receptors. Eur J Pharmacol. 396:2000;39-42.