Ligation of IFN-γ-induced HLA-DR molecules on fibroblasts induces RANTES expression via c-Jun N-terminal kinase (JNK) pathway

Cytokine

Volumn 22, Issue 5, 2003, Pages 107-115

  Meguro, Michio ^a   Nishimura, Fusanori ^a   Ohyama, Hideki ^b   Takashiba, Shogo ^a   Murayama, Yoji ^a   Matsushita, Sho ^b  

^a OKAYAMA UNIVERSITY   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Fibroblasts; HLA DR molecule; Jun N terminal kinase 2; RANTES

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ENZYME INHIBITOR; GAMMA INTERFERON; GENISTEIN; HLA ANTIBODY; HLA DR ANTIGEN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; RANTES; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL ASSAY; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FIBROBLAST; GENE EXPRESSION; GENETICS; GINGIVA; HUMAN; HUMAN CELL; METABOLISM; MOLECULAR BIOLOGY; MOLECULAR WEIGHT; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 0038046684     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-4666(03)00123-6     Document Type: Article

References (17)

1. Ohyama H., Nishimura F., Meguro M., Takashiba S., Murayama Y., Matsushita S. Counter-antigen presentation: fibroblasts produce cytokines by signaling through HLA class II molecules without inducing T-cell proliferation. Cytokine. 17:2002;75-181.
2. Matsuoka T., Tabata H., Matsushira S. Monocytes are differentially activated through HLA-DR, -DQ, and -DP molecules via mitogen-activated protein kinases. J Immunol. 166:2001;2202-2208.
3. Tabata H., Matsuoka T., Endo F., Nishimura Y., Matsushita S. Ligation of HLA-DR molecules on B cells induces enhanced expression of IgM heavy chain genes in association with Syk activation. J Biol Chem. 275:2000;34998-35005.
4. Morio T., Geha R.S., Chatila T.A. Engagement of MHC class II molecules by staphylococcal superantigens activates src-type protein tyrosine kinases. Eur J Immunol. 24:1994;651-658.
5. Rich T., Lawler S.E., Lord J.M., Blancheteau V.M., Charron D.J., Mooney N.A. HLA class II-induced translocation of PKC alpha and PKC beta II isoforms is abrogated following truncation of DR beta cytoplasmic domains. J Immunol. 159:1997;3792-3798.
6. Kujime K., Hashimoto S., Gon Y., Shimizu K., Horoe T. p38 mitogen-activated protein kinase and c-jun-NH2-terminal kinase regulate RANTES production by influenza virus-infected human bronchial epithelial cells. J Immunol. 164:2000;3222-3228.
7. Furuichi S., Hashimoto S., Gon Y., Matsumoto K., Horie T. p38 mitogen-activated protein kinase and c-jun-NH2-terminal kinase regulate interleukin-8 and RANTES production in hyperosmolarity stimulated human bronchial epithelial cells. Respirology. 7:2002;193-200.
8. Han Z., Boyle D.L., Chang L., Bennett B., Karin M., Yang L., et al. C-jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest. 108:2001;73-81.
9. Shiozawa S., Shiozawa K., Fujita T. Presence of HLA-DR antigen on synovial type A and B cells: an immunoelectron microscopic study in rheumatoid arthritis, osteoarthritis and normal traumatic joints. Immunology. 50:1983;587-594.
10. Barber S., Powell R.N., Seymour G.J. Surface markers of human gingival fibroblasts in vitro. Characterization and modulation by enzymes and bacterial products. J Oral Pathol. 13:1984;221-230.
11. Lévéille C., Castaigne J-B, Charron D., Al-Daccak R. MHC class II isotype-specific signaling complex on human B cells. Eur J Immunol. 32:2002;2282-2291.
12. Lang P., Stolpa J.C., Freiberg B.A., Crawford F., Kappler J., Kupfer A., et al. TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-α/β dimmers. Science. 291:2001;1537-1540.
13. Bennett B.L., Sakaki D.T., Murray B.W., O'Leary E.C., Sakata S.T., Xu W., et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci USA. 98:2001;13681-13686.
14. Schall T.J., Bacon K., Goeddel D.V. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature. 347:1990;669-671.
15. Tanaka J., Nomiyama H., Yamamoto T., Hamada F., Kambara T. T-cell chemotactic activity of cytokine LD78: a comparative study with interleukin-8, a chemotactic factor for the T-cell CD45RA+phenotype. Int Arch Allergy Immunol. 100:1993;201-208.
16. Roth S.J., Diacovo T.G., Brenner M.B., Rosat J.P., Buccola J., Morita C.T., et al. Transendothelial chemotaxis of human alpha/beta and gamma/delta T lymphocytes to chemokines. Eur J Immunol. 28:1998;104-113.
17. Nishimura F., Terranova V.P. Comparative study of the chemotactic responses of periodontal ligament cells and gingival fibroblasts to polypeptide growth factors. J Dent Res. 75:1996;986-992.