Molecular simulation of a single-chain antibody against AChE to explore molecular basis of inhibitory effect of 3F3 McAb on enzyme activity

Acta Pharmacologica Sinica

Volumn 24, Issue 5, 2003, Pages 460-466+480

  Guo, Chong Zhi ^a   Wu, Jun Hua ^a   Wang, Yu Xia ^a   Hu, Yuan Dong ^a   Li, Song ^a   Sun, Man Ji ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Acetylcholinesterase; Computer simulation; Gene expression; Monoclonal antibodies

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 3F3; RECOMBINANT ANTIBODY; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; COMPUTER SIMULATION; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR MODEL; NONHUMAN; THREE DIMENSIONAL IMAGING;

ACETYLCHOLINESTERASE; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CHOLINESTERASE INHIBITORS; COMPUTER SIMULATION; HYBRIDOMAS; IMMUNOGLOBULIN FRAGMENTS; MOLECULAR CONFORMATION;

EID: 0038031883     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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