메뉴 건너뛰기




Volumn 51, Issue 5, 2003, Pages 439-444

Clinical and pharmacologic study of tributyrin: An oral butyrate prodrug

Author keywords

Butyrate; Differentiating agent; Histone deacetylase inhibitor

Indexed keywords

BUTYRIC ACID; NSC 661583; PRODRUG; TRIBUTYRIN;

EID: 0038018593     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-003-0580-5     Document Type: Article
Times cited : (81)

References (18)
  • 1
    • 0019296097 scopus 로고
    • Butyric acid: A small fatty acid with diverse biologic functions
    • Prasad K (1980) Butyric acid: a small fatty acid with diverse biologic functions. Life Sci 27:1351-1358
    • (1980) Life Sci , vol.27 , pp. 1351-1358
    • Prasad, K.1
  • 2
    • 0035283749 scopus 로고    scopus 로고
    • Modulation of cell cycle-related protein expression by sodium butyrate in human non-small cell lung cancer cell lines
    • Pellizzaro C, Coradini D, Daniotti A, Abolafio G, Daidone MG (2001) Modulation of cell cycle-related protein expression by sodium butyrate in human non-small cell lung cancer cell lines. Int J Cancer 91:654-657
    • (2001) Int J Cancer , vol.91 , pp. 654-657
    • Pellizzaro, C.1    Coradini, D.2    Daniotti, A.3    Abolafio, G.4    Daidone, M.G.5
  • 3
    • 0033740191 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors decrease proliferation and modulate cell cycle gene expression in normal mammary epithelial cells
    • Davis T, Kennedy C, Chiew YE, Clarke CL, deFazio A (2000) Histone deacetylase inhibitors decrease proliferation and modulate cell cycle gene expression in normal mammary epithelial cells. Clin Cancer Res 6:4334-4342
    • (2000) Clin Cancer Res , vol.6 , pp. 4334-4342
    • Davis, T.1    Kennedy, C.2    Chiew, Y.E.3    Clarke, C.L.4    DeFazio, A.5
  • 5
    • 0035953181 scopus 로고    scopus 로고
    • Antitumor activity of tributyrin in murine melanoma model
    • Giermasz A, Nowis D, Jalili A, et al (2001) Antitumor activity of tributyrin in murine melanoma model. Cancer Lett 64:143-148
    • (2001) Cancer Lett , vol.64 , pp. 143-148
    • Giermasz, A.1    Nowis, D.2    Jalili, A.3
  • 6
    • 0033819161 scopus 로고    scopus 로고
    • Tributyrin induces differentiation, growth arrest and apoptosis in androgen sensitive and androgen-resistant human prostate cancer cell lines
    • Maier, Reich E, Martin R, et al (2000) Tributyrin induces differentiation, growth arrest and apoptosis in androgen sensitive and androgen-resistant human prostate cancer cell lines. Int J Cancer 88:245-251
    • (2000) Int J Cancer , vol.88 , pp. 245-251
    • Maier1    Reich, E.2    Martin, R.3
  • 7
    • 0031954530 scopus 로고    scopus 로고
    • Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors
    • Conley BA, Egorin MJ, Tait N, et al (1998) Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors. Clinical Cancer Res 4:629-634
    • (1998) Clinical Cancer Res , vol.4 , pp. 629-634
    • Conley, B.A.1    Egorin, M.J.2    Tait, N.3
  • 9
    • 3643104150 scopus 로고    scopus 로고
    • Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase
    • Warrell RP, He L-Z, Richon V, Calleja E, Pandolfi PP (1998) Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase. J Natl Cancer Inst 90:1621-1625
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1621-1625
    • Warrell, R.P.1    He, L.-Z.2    Richon, V.3    Calleja, E.4    Pandolfi, P.P.5
  • 10
    • 0028260120 scopus 로고
    • Butyrate as a differentiating agent: Pharmacokinetics, analogues and current status
    • Newmark HL, Lupton JR, Young CW (1994) Butyrate as a differentiating agent: pharmacokinetics, analogues and current status. Cancer Lett 78:1-5
    • (1994) Cancer Lett , vol.78 , pp. 1-5
    • Newmark, H.L.1    Lupton, J.R.2    Young, C.W.3
  • 11
    • 0028339741 scopus 로고
    • Tributyrin: A prodrug of butyric acid for potential clinical application in differentiation therapy
    • Chen Z-X, Breitman T (1994) Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy. Cancer Res 54:3494-3499
    • (1994) Cancer Res , vol.54 , pp. 3494-3499
    • Chen, Z.-X.1    Breitman, T.2
  • 12
    • 0027078611 scopus 로고
    • A short term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders
    • Perrine SP, Ginger GD, Faller DV, et al (1993) A short term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders. N Engl J Med 328:81-86
    • (1993) N Engl J Med , vol.328 , pp. 81-86
    • Perrine, S.P.1    Ginger, G.D.2    Faller, D.V.3
  • 13
    • 0000403664 scopus 로고
    • Phenylbutyrate (PB) for refractory solid tumors: Phase I clinical and pharmacologic evaluation of intravenous and oral PB
    • Carducci M, Bowling MK, Eisenberger M, et al. (1987) Phenylbutyrate (PB) for refractory solid tumors: phase I clinical and pharmacologic evaluation of intravenous and oral PB. Anticancer Res 17:3972-3973
    • (1987) Anticancer Res , vol.17 , pp. 3972-3973
    • Carducci, M.1    Bowling, M.K.2    Eisenberger, M.3
  • 14
    • 0030914275 scopus 로고    scopus 로고
    • Cows' milk fat components as potential anticarcinogenic agents
    • Parodi PW (1997) Cows' milk fat components as potential anticarcinogenic agents. J Nutr 127:1055-1060
    • (1997) J Nutr , vol.127 , pp. 1055-1060
    • Parodi, P.W.1
  • 15
    • 0034596309 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells
    • Marks PA, Richon VM, Rifkind RA (2001) Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells. J Natl Cancer Inst 92:1210-1216
    • (2001) J Natl Cancer Inst , vol.92 , pp. 1210-1216
    • Marks, P.A.1    Richon, V.M.2    Rifkind, R.A.3
  • 16
    • 0033861924 scopus 로고    scopus 로고
    • Tributyrin plus all-transretinoic acid efficiently induces fetal hemoglobin expression in human erythroleukemia cells
    • Witt O, Schmejkal S, Pekrun A (2000) Tributyrin plus all-transretinoic acid efficiently induces fetal hemoglobin expression in human erythroleukemia cells. Am J Hematol 64:319-321
    • (2000) Am J Hematol , vol.64 , pp. 319-321
    • Witt, O.1    Schmejkal, S.2    Pekrun, A.3
  • 17
    • 0035020905 scopus 로고    scopus 로고
    • Tributyrin enhances the cytotoxic activity of interleukin2/interleukin 12-stimulated human natural killer cells against LS 174T colon cancer cells in vitro
    • Schroder CP, Maurer HR (2001) Tributyrin enhances the cytotoxic activity of interleukin2/interleukin 12-stimulated human natural killer cells against LS 174T colon cancer cells in vitro. Cancer Immunol Immunother 50:69-76
    • (2001) Cancer Immunol Immunother , vol.50 , pp. 69-76
    • Schroder, C.P.1    Maurer, H.R.2
  • 18
    • 0031730897 scopus 로고    scopus 로고
    • Activity of pivaoyloxymethyl butyrate, a novel anticancer agent, on primary human tumor colony forming units
    • Siu LL, Von Hoff DD, Rephaeli A, et al (1998) Activity of pivaoyloxymethyl butyrate, a novel anticancer agent, on primary human tumor colony forming units. Invest New Drugs 16:113-119
    • (1998) Invest New Drugs , vol.16 , pp. 113-119
    • Siu, L.L.1    Von Hoff, D.D.2    Rephaeli, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.