Improving scar quality: A prospective clinical study

Aesthetic Plastic Surgery

Volumn 26, Issue 6, 2002, Pages 470-476

  Atiyeh, Bishara S ^a   Ioannovich, John ^b   Al Amm, Christian A ^b   El Musa, Kusai A ^b   Dham, Ruwayda ^b  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^b NONE

Author keywords

MEBO; Scar evaluation; Scar formation

Indexed keywords

ANTIBIOTIC AGENT; FUSIDATE SODIUM; MOIST EXPOSED BURN OINTMENT; PROPOLIS; SESAME SEED OIL; SITOSTEROL; ANTIINFECTIVE AGENT; FUSIDIC ACID; SITOSTEROL DERIVATIVE;

ARTICLE; CHEMOPROPHYLAXIS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; HUMAN; OINTMENT; PLASTIC SURGERY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PUBLICATION; SCAR FORMATION; SKIN SCAR; SPLIT THICKNESS SKIN GRAFT; SURGICAL INJURY; TREATMENT OUTCOME; VISUAL ANALOG SCALE; WOUND HEALING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; FACE; PATHOLOGY; PATHOPHYSIOLOGY; SCAR; SKIN; SUTURE; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANTI-BACTERIAL AGENTS; CICATRIX; FACE; FUSIDIC ACID; HUMANS; OINTMENTS; PROSPECTIVE STUDIES; SITOSTEROLS; SKIN; SUTURES; WOUND HEALING;

EID: 0038012949     PISSN: 0364216X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00266-002-2019-5     Document Type: Article

References (48)

1. Ahn ST, Monafo WW, Mustoe TA: Topical silicone gel for the prevention and treatment of hypertrophic scar. Arch Surg 126:499, 1991
2. Alster TS, Kurban AK, Grove GL, et al.: Alteration of argon laser-induced scars by the pulsed dye laser. Lasers Surg Med 13:368, 1993
3. Alster TS: Improvement of erythematous and hypertrophic scars by the 585 nm pulsed dye laser. Ann Plast Surg 32:186, 1994
4. Alster TS, West TB: Treatment of scars: a review. Ann Plast Surg 39:428, 1997
5. Alster TS: Laser treatment of hypertrophic scars, keloids, and striae. Dermatol Clin 15:419, 1997
6. Anderson RR, Parrish JA: Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science 22:524, 1983
7. Ang ES, Lee ST, Gan CS, See P, et al.: The role of alternative therapy in the management of partial thickness burns of the face experience with the use of moist exposed burn ointment (MEBO) compared with silver sulphadiazine. Ann Acad Med Singapore 29:7, 2000
8. Atiyeh BS, Ioannovich J, Al Amm CA: Pansements de sites donneurs de greffe de peau mince: Resultats preliminaires dune etude clinique limitee comparative de "MEBO" et de "Sofra-Tulle. Brulures Revue Française de brûlologie 1:155, 2000
9. Atiyeh BS, Ghanimeh G, Kaddoura IL, Al Amm C, Ioannovich J: Letter to the editor: Split thickness skin graft donor site dressing: Preliminary results of controlled clinical comparative study of MEBO and Sofra-Tulle. Ann Plast Surg 46:87, 2001
10. Beausang E, Floyd H, Dunn KW, Orton GI, et al.: A new quantitative scale for clinical scar assessment. Plast Reconstr surg 102:1954, 1998
11. Carr-Collins JA: Pressure techniques for the prevention of hypertrophic scar. Clin Plast Surg 19:733, 1992
12. Chang CC, Kuo YF, Chiu HC, Lee JL: Hydration not silicone, modulates the effects of keratinocytes on fibroblasts. J Surg Res 59:705, 1995
13. Cohen KI: Wound healing: Key advances in research and clinical care. Contemp Surg Suppl Sept:2, 2000
14. Cohen KI: The biology of wound healing. Contemp Surg Suppl Sept:4-8, 2000
15. Cohen KI, Diegelmann RF, Yager DR, Wornum III IL, et al.: Wound care and wound healing. In: Spencer S, Galloway DF (eds). Principles of surgery. McGraw-Hill: New York, p 269
16. Cohen IK, McCoy BJ: The biology and control of surface overhealing. World J Surg 4:289, 1990
17. Cruz-Korchin NI: Effectiveness of silicone sheets in the prevention of hypertrophic breast scars. Ann Plast Surg 37:345, 1996
18. Datubo-Brown D: Keloids. A review of the literature. Brit J Plast Surg 43:70, 1990
19. Davy RB, Wallis KA, Bowering K: Adhesive contact media: an update on graft fixation and bura scar management. Burns 17:313, 1991
20. Garcia-Velasco M, Ley R, Mutch D, Surkes N, Williams HB: Compression treatment of hypertrophic scars in burned patients. Can J Surg 21:450, 1978
21. Gold MH: A controlled clinical trial of topical silicone gel sheeting in the treatment of hypertrophic scars and keloids. J Am Acad Derrnatol 30:506, 1994
22. Griffith BH: The treatment of keloids with triamcinolone acetonide. Plast Reconstr Surg 38:202, 1966
23. Grinnel F: Fibroblasts, myofibroblasts, and wound contraction. J Cell Biol 124:401, 1994
24. Huang QS, Zhou G, Su BP, Huang EX: A comparative study of fibronectin and MEBO in the treatment of experimental rabbit corneal alkaline burn. Chinese J Burns Wounds Surf Ulcers 1:18, 1995
25. Ioannovich J, Tsati E, Tsoutsos D, Frangia K, et al.: Moist exposed burn therapy: evaluation of the epithelial repair process (an experimental model). Ann Burns Fire Disast 8:3, 2000
26. Janssen de Limpens AM: The local treatment of hypertrophic scars and keloids with retinoic acid. Br J Dermatol 103:319, 1980
27. Kovalic JJ, Perez CA: Radiation therapy following keloidectomy: A 20-year experience. Int J Radiat Oncol Biol Phys 17:77, 1989
28. Kischer H, Shetlar MR, Shetlar CL: Alteration of hypertrophic sternal scars induced by mechanical pressure. Arch Dermatol 8:60, 1975
29. Krusche T, Worret WI: Mechanical properties of keloids in vivo during treatment with intralesional triamcinolone acetonide. Arch Dermatol Res 287:289, 1995
30. Larrabee Jr, WF, East CA, Jaffe HS, Stephenson C, Peterson KE: Intralesional interferon gamma treatment for keloids and hypertrophic scars. Arch Otolaryngol Head Neck Surg 116:1159, 1990
31. Larson DL, Abston S, Evans EB, Dobrkovsky M, Linares HA: Techniques for decreasing scar formation and contractures in the burned patient. J Trauma 11:807, 1971
32. Lawrence WT: In search of the optimal treatment of keloids: report of a series and a review of the literature. Ann Plast Surg 27:164, 1991
33. Li L: Experiment on inhibiting constriction of the ileum from a white mouse. Chinese J Burns Wounds Surf Ulcers 1:50, 1990
34. Magliacani G, Stella M, Costagliola C, Trombotto C, et al.: Post-burn pathologic scar: Clinical aspects and therapeutic approach. Ann Burn Fire Disasters 10:105, 1997
35. Mast BA: Repair of specific tissues: The skin. In: Diegelman RF and Lindblad WJ (eds) Wound healing: Biochemical and clinical aspects. Saunders Co: Philadelphia, p 344, 1992
36. McCraw JB, McCraw JA, McMcllin A, Bettencourt N: Prevention of unfavorable scars using early pulse dye laser treatments: A preliminary report. Ann Plast Surg 42:7, 1999
37. Murray JC: Sears and keloids. Dermatol Clin 11:697, 1993
38. Muti E, Ponzio E: Cryotherapy in the treatment of keloids. Ann Plast Surg 11:227, 1983
39. Nissen FB, Spauwen PHM, Robinson PH, Fidler V, et al.: The use of silione occlusive sheeting (Sil-K) and silicone occlusive gel (Epiderm) in the prevention of hypertrophic scar formation. Plast Reconstr Surg 102:1962, 1998
40. Peacock E: Pharmacologic control of surface scarring in human beings. Ann Surg 193:592, 1981
41. Peacock E: Wound repair. Saunders Co: Philadelphia, p 485, 1984
42. Qu YY, Wang YP, Qiu SC, et al.: Experimental research on the mechanism of the effect of MEBO. Chinese J Burns Wounds Surf Ulcers 4:4, 1997
43. Robb EC, Waymack JP, Warden GD, Nathan P, et al.: A new model for studying the development of human hypertrophic burn scar formation. J Burn Care Rehabil 8:371, 1987
44. Sherris DA, Larrabee Jr, WF, Murakami CS: Management of scar contractures, hypertrophic scars, and keloids. Otolaryngol Clin North Am 28:1057, 1995
45. Topol BM, Lewis VL, Benvensite K: The use of antihistamine to retard growth of fibroblasts derived from human skin, scar and keloid. Plast Reconstr Surg 68:227, 1981
46. Wang GS, Zhang YM, Liu RS, et al.: Experimental study of the effect of MEBO on blood rheology in the treatment of burned rabbits. Chinese J Burns Wounds Surf Ulcers 4:30, 1993
47. Wang GS, Jian WG, Xu XS, et al.: The exploration of pathological changes and their mechanism of experimentally burned rabbits after treatment. Chinese J Burns Wounds Surf Ulcers 3:7, 1992
48. Weber S, Kruger-Kragasakes S, Grabbe J, Zuberbier T, et al.: Mast cells. Int J Dermatol 34:1, 1995