Ototoxicity from the aminoglycoside-heparin/citrate locks applied for the prevention of hemodialysis catheter-related infections

Journal of Vascular Access

Volumn 4, Issue 1, 2003, Pages 35-36

  Saxena, Anil K ^a  

^a KING FAHAD HOSPITAL   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE; CEPHALOSPORIN; CITRIC ACID; GENTAMICIN; HEPARIN; TOBRAMYCIN;

BACTERIAL COLONIZATION; CATHETER INFECTION; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG EXCRETION; DRUG MECHANISM; HEMODIALYSIS; HUMAN; LETTER; OTOTOXICITY; PERCEPTION DEAFNESS; SEPTICEMIA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; VASCULAR ACCESS;

EID: 0037986745     PISSN: 11297298     EISSN: None     Source Type: Journal    
DOI: 10.1177/112972980300400108     Document Type: Letter

References (5)

1. Capdevila JA, Segarra A, Planes AM. Successful treatment of hemodialysis catheter related sepsis without catheter removal. Nephrol Dial Transplant 1993; 8: 231-4.
2. Dogra GK, Herson H, Hutchison B, et al. Prevention of tunneled hemodialysis catheter-related infections using catheter-restricted filling with gentamicin and citrate: A randomized controlled study. J Am Soc Nephrol 2002; 13: 2133-9.
3. Saxena AK, Panhotra BR, Naguib M. Sudden irreversible sensory-neural hearing loss in a patient with diabetes receiving amikacin as an antibiotic-heparin lock. Pharmacotherapy 2002; 22: 105-8.
4. Beaubien AR, Desjardins S, Ormsby E, Bayne A, Carrier K, Cauchy MJ. Delay in hearing loss following drug administration: a consistent feature of amikacin toxicity. Acta Otolaryngol 1990; 109: 345-7.
5. Basile AS, Huang JM, Xie C, et al. N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss. Nat Med 1996; 2: 1338-43.