Is plasma procalcitonin ready for prime time in the pediatric intensive care unit?

Pediatric Critical Care Medicine

Volumn 4, Issue 1, 2003, Pages 118-119

  Mariscalco, M Michele ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN; PROCALCITONIN; PROTEIN PRECURSOR;

BLOOD; HUMAN; INTENSIVE CARE; MICROBIOLOGY; NOTE; PREDICTION AND FORECASTING; SEPSIS; SEPTIC SHOCK;

CALCITONIN; HUMANS; INTENSIVE CARE UNITS, PEDIATRIC; PREDICTIVE VALUE OF TESTS; PROTEIN PRECURSORS; SEPSIS; SHOCK, SEPTIC;

EID: 0037983074     PISSN: 15297535     EISSN: 19473893     Source Type: Journal    
DOI: 10.1097/00130478-200301000-00025     Document Type: Editorial

References (15)

1. Assicot M, Grendel D, Carsin H, et al: High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993; 341: 515-518
2. Meisner M: Pathobiochemistry and clinical use of procalcitonin. Clin Chim Acta 2002; 323: 17-29
3. Monneret G, Laroche B, Bienvenu J: Procalcitonin is not produced by circulating blood cells. Infection 1999; 27: 34-35
4. Braq S, Machason M: Calcitonin gene expression in normal human liver. FEBS Lett 1993; 331: 14-18
5. Nijsten MW, Olinga P, The TH, et al: Procalcitonin behaves as a fast responding acute phase protein in vivo and in vitro. Crit Care Med 2000; 28: 3659-3663
6. Hoffmann G, Totzke G, Seibel M, et al: In vitro modulation of inducible nitric oxide synthase gene expression and nitric oxide synthesis by procalcitonin. Crit Care Med 2001; 29: 112-116
7. Nylen NS, Whang KT, Snider RH, et al: Mortality is increased by procalcitonin and decreased by an antiserum reactive to procalcitonin in experimental sepsis. Crit Care Med 1998; 26: 1001-1006
8. Harbarth S, Holeckova K, Froidevaux C, et al: Diagnostic value of procalcitonin, interleukin-6, and interleukin 8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med 2001; 164: 396-402
9. Müller B, Becker KL, Schächinger H, et al: Calcitonin precursors are reliable markers of sepsis in a medical intensive unit. Crit Care Med 2000; 28: 977-983
10. Ugarte H, Silva E, Mercan D, et al: Procalcitonin used as a marker of infection in the intensive care unit. Crit Care Med 1999; 27: 498-504 Ovid Full Text
11. Meisner M, Tschaikowsky K, Palmaers T, et al: Comparison of procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations at different SOFA scores during the course of sepsis and MODS. Crit Care 1999; 3: 45-50
12. Wanner GA, Keel M, Steckholzer U, et al: Relationship between procalcitonin plasma levels and severity of injury, sepsis, organ failure and mortality in injured patients. Crit Care Med 2000; 28; 950-957
13. Claeys R, Vinken S, Spapen H, et al: Plasma procalcitonin and C-reactive protein in acute septic shock: Clinical and biological correlates. Crit Care Med 2002; 30: 757-762
14. Hatherhill M, Tibby S, Turner C, et al: Procalcitonin and cytokine levels: Relationship to organ failure and mortality in pediatric septic shock. Crit Care Med 2000; 28: 2591-2594
15. Han YY, Doughty LA, Kofos D, et al: Procalcitonin is persistently increased among children with poor outcome from bacterial sepsis. Pediatr Crit Care Med 2003; 4: 21-25