Zinc binding in peptide models of angiotensin-I converting enzyme active sites studied through 1H-NMR and chemical shift perturbation mapping

Biopolymers

Volumn 69, Issue 2, 2003, Pages 244-252

  Galanis, Athanassios S ^a   Spyroulias, Georgios A ^a   Pierattelli, Roberta ^b   Tzakos, Andreas ^c   Troganis, Anastassios ^c   Gerothanassis, Ioannis P ^c   Pairas, George ^a   Manessi Zoupa, Evy ^a   Cordopatis, Paul ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF IOANNINA   (Greece)

Author keywords

Angiotensin I converting enzyme; Chemical shift index; NMR; Renin angiotensin system; Zinc binding motifs

Indexed keywords

ENZYME KINETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PERTURBATION TECHNIQUES; SOLUTIONS; SYNTHESIS (CHEMICAL); ZINC;

CHEMICAL SHIFT;

POLYPEPTIDES;

9 FLUORENYLMETHOXYCARBONYL DERIVATIVE; CARBONYL DERIVATIVE; DIPEPTIDYL CARBOXYPEPTIDASE; FLUORINE DERIVATIVE; UNCLASSIFIED DRUG; ZINC;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVE SITE; METAL BINDING; PROTEIN BINDING; PROTEIN MOTIF; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; HUMANS; ISOENZYMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PEPTIDYL-DIPEPTIDASE A; PROTEIN CONFORMATION; PROTONS; SEQUENCE HOMOLOGY, AMINO ACID; SOLUTIONS; THERMOLYSIN; ZINC;

EID: 0037980444     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/bip.10362     Document Type: Article

References (39)

1. Burell, L. M.; Johnston, C. I. In Drugs, Enzymes, and Receptors of the Renin-Angiotensin System: Celebrating a Century of Discovery; Husain, A., Graham, R. M., Eds.; Harwood Academic Publishers, The Netherlands, 2000; pp 191-200.
2. Corvol, P.; Williams T. A. In Handbook of Proteolytic Enzymes; Barrett, A. J., Rawlings, N. D., Woessner, J. F., Eds.; Academic Press: New York, 1998; pp1066-1076.
3. Sourbier, F.; Alhenc-Gelas, F.; Hubert, C.; Allegrini, J.; John, M.; Tregear, G.; Corvol, P. Proc Natl Acad Sci USA 1988, 85, 9386-9390.
4. Piquilloud, Y.; Reinharz, A.; Roth, M. Biochim Biophys Acta 1970, 206, 136-142.
5. Soffer, R. L. Annu Rev Biochem 1976, 45, 73-94.
6. Hooper, N. M. FEBS Lett 1994, 354, 1-6.
7. Barrett, A. J.; Rawlings, N. D.; Woessner, J. F. In Handbook of Proteolytic Enzymes; Academic Press: New York, 1998; pp 992-993.
8. Yang, H. Y. Y.; Erdös, E. G.; Levin, V. A. Biochim Biophys Acta 1970, 214, 374-376.
9. Skeggs, L. T.; Kahn, J. R.; Shumway, N. P. J Exp Med 1956, 103, 295-299.
10. Bünning, P.; Riordan, J. F. Biochemistry 1983, 22, 110-116.
11. Ehlers, M. R. W.; Fox, E. A.; Strydom, D. J.; Riordan, J. F. Proc Natl Acad Sci USA 1989, 86, 7741-7745.
12. Lattion, A. L.; Soubrier, F.; Allegrini, J.; Hubert, C.; Corvol, P.; Alhenc-Gelas, F. FEBS Lett 1989, 252, 99-104.
13. Ehlers, M. R.; Riordan, J. F. Biochemistry 1991, 30, 7118-7126.
14. Rieder, M. J., Taylor, S. L.; Clark, A. G.; Nickerson, D. A. Nat Genet 1999, 22, 59-62.
15. Wei, L.; Alhenc-Gelas, F.; Corvol, P.; Clauser, E. J Biol Chem 1991, 266, 9002-9008.
16. Valle, B. L.; Auld, D. S. Proc Natl Acad Sci USA 1990, 87, 220-224.
17. Auld, D. S. In Handbook on Metalloproteins; Bertini, I., Sigel, A., Sigel, H., Eds.; Marcel Dekker: New York, Basel, 2001; pp 881-959.
18. Williams, T. A.; Corvol, P.; Soubrier, F. J Biol Chem 1994, 269, 29430-29434.
19. Matthews, B. W. Acc Chem Res 1988, 21, 333-340.
20. Colman, P. M.; Jansonius, J. N.; Matthews, B. W. J Mol Biol 1972, 70, 701-724.
21. Michaud, A.; Chauvet, M. T.; Corvol, P. Biochem Pharmacol 1999, 57, 611-618.
22. Marcic, B.; Deddish, P. A.; Jackman, H. L.; Erdös, E. G. Hypertension 1999, 33, 835-843.
23. Araujo, M. C.; Melo, R. L.; Cesari, M. H.; Juliano, M. A.; Juliano, L.; Carmona, A. K. Biochemistry 2000, 39, 8519-8525.
24. Holland, D. R.; Hausrath, A. C.; Juers, D.; Matthews, B. W. Protein Sci 1995, 4, 1955-1965.
25. Pelmenschikov, V.; Blomberg, M. R. A.; Siegbahn, P. E. M. J Biol Inorg Chem 2002, 7, 284-298.
26. Papazacharias, S.; Pairas, G.; Kouimtzoglou, E.; Dermitzaki, E.; Manessi-Zoupa, E.; Gravanis, A.; Cordopatis, P. In Peptides 2000; Martinez, J., Fehrentz, J.-A., Eds.; EDK: Paris, 2001; pp 933-934.
27. King, D. S.; Fields, C. G.; Fields, G. B. Int J Pept Protein Res 1990, 36, 255-266.
28. Wishart, D., Sykes, B.; Richards, F. J Mol Biol 1991, 222, 311-333.
29. Wishart, D., Sykes, B.; Richards, F. Biochemistry 1992, 31, 1647-1651.
30. Zuiderweg E. R. P. Biochemistry 2002, 41, 1-7.
31. Matthews, B. W.; Weaver, L. H.; Kester, W. R. J Biol Chem 249, 1974, 8030-8044.
32. Holmes, M. A.; Matthews, B. W. J Mol Biol 1982, 160, 623-639.
33. Garnier, J.; Osguthorpe, D. J.; Robson, B. J Mol Biol 1978, 120, 97-120.
34. Gibrat, J. F.; Garnier, J.; Robson, B. J Mol Biol 1987, 198, 425-443.
35. Combet, C.; Blanchet, C.; Geourjon, C.; Deléage, G. TIBS 2000, 25, 147-150.
36. Koradi, R.; Billeter, M.; Wüthrich, K. J Mol Graph 1996, 14, 51-55.
37. Marion, D.; Wüthrich, K. Biochem Biophys Res Commun 1983, 113, 967-974.
38. Natesh, R.; Schwager, S. L. U.; Sturrock, E. D.; Acharya, K. R. Nature 2003, 421, 551-554.
39. Kim, H. M.; Shin, D. R.; Yoo, O. J.; Lee, H.; Lee, J. O. FEBS Lett 2003, 538, 65-70.