Co-ordinate regulation of sterol biosynthesis enzyme activity during accumulation of sterols in developing rape and tobacco seed

Planta

Volumn 216, Issue 4, 2003, Pages 707-715

  Harker, Mark ^a   Hellyer, Amanda ^a   Clayton, John C ^a   Duvoix, Annelyse ^a   Lanot, Alexandra ^a   Safford, Richard ^a  

^a UNILEVER RESEARCH   (United Kingdom)

Author keywords

Brassica; Development; Nicotiana Phytosterol; Seed

Indexed keywords

BIOSYNTHESIS; COENZYMES; ESTERS; SEED; TOBACCO;

SEED TISSUES;

PLANTS (BOTANY);

BRASSICA; BRASSICA NAPUS; NICOTIANA; NICOTIANA TABACUM; SINAPIS ARVENSIS;

CHOLESTEROL ACYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; METHYLTRANSFERASE; PHYTOSTEROL;

ARTICLE; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PLANT SEED; RAPESEED; TIME; TOBACCO;

BRASSICA NAPUS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; METHYLTRANSFERASES; PHYTOSTEROLS; SEEDS; STEROL O-ACYLTRANSFERASE; TIME FACTORS; TOBACCO;

EID: 0037977901     PISSN: 00320935     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00425-002-0913-3     Document Type: Article

References (29)

1. Bach TJ (1986) Hydroxymethyl glutaryl-CoA reductase, a key enzyme in phytosterol synthesis? Lipids 21:82-88
2. Bach TJ, Benveniste P (1997) Cloning of cDNAs or genes encoding enzymes of sterol biosynthesis from plants and other eukaryotes: Heterologous expression and complementation analysis of mutations for functional characterization. Prog Lipid Res 36:197-226
3. Bach TJ, Weber T, Motel A (1990) Some properties of enzymes involved in the biosynthesis and metabolism of 3-hydroxy-3-methylglutaryl-CoA in plants. Recent Adv Phytochem 24:1-82
4. Bloch KE (1983) Sterol structure and membrane function. CRC Crit Rev Biochem 14:47-91
5. Bouvier-Nave P, Benveniste P (1995) Sterol acyl transferase and steryl ester hydrolase activities in a tobacco mutant which overproduces sterols. Plant Sci 110:11-19
6. Chappell J, Wolf F, Proulx J, Cuellar R, Saunders C (1995) Is the reaction catalysed by 3-hydroxy-3-methylglutaryl-CoA reductase a rate-limiting step for isoprenoid biosynthesis in plants? Plant Physiol 109:1337-1343
7. Demel RA, DeKryff B (1976) Function of sterols in membranes. Biochim Biophys Acta 457:109-132
8. Fujioka S, Sakurai A (1997) Brassinosteroids. Nat Prod Rep 14:1-10
9. Gershenzon J, Croteau R (1990) Regulation of monoterpene biosynthesis in higher plants. Recent Adv Phytochem 24:99-160
10. Gershenzon J, Croteau R (1993) Terpenoid biosynthesis: the basic pathway and formation of monoterpenes, sesquiterpenes, and diterpenes. In: Tower TS Jr (ed) Lipid metabolism in plants. CRC Press, Boca Raton, pp 339-388
11. Gondet L, Bronner R, Benveniste P (1994) Regulation of sterol content in membranes by subcellular compartmentation of steryl-esters accumulating in a sterol-overproducing tobacco mutant. Plant Physiol 105:509-518
12. Gray JC (1987) Control of isoprenoid biosynthesis in higher plants. Adv Bot Res 14:25-91
13. 24(25)-sterol methyl transferase. II. Inhibition by analogs of the transition state coordinate. J Biol Chem 267:25856-25863
14. Kalinowska M, Wojciechowski ZA (1983) The occurrence of sterol-ester hydrolase activity in roots of white mustard seedlings. Phytochemistry 22:59-63
15. Maillot-Vernier P, Gondet L, Schaller, H, Benveniste P, Belliard G (1991) Genetic study and further biochemical characterization of a tobacco mutant that overproduces sterols. Mol Gen Genet 231:33-40
16. Moore KB, Oishi KK (1993) Characterization of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity during maize seed development, germination, and seedling emergence. Plant Physiol 101:485-491
17. Nes WD (1990) Control of sterol biosynthesis and its importance to developmental regulation and evolution. Recent Adv Phytochem 24:283-327
18. Nes WD (2000) Sterol methyl transferase: enzymology and inhibition. BBA-Mol Biol Lipid 1529:63-88
19. Nes WD, Venkatramesh M (1999) Enzymology of phytosterol transformations. Crit Rev Biochem Mol Biol 34:81-93
20. Nes WD, Janssen GG, Bergenstrahle A (1991) Structural requirements for transformation of substrates by the (S)-adenosyl-L-methionine:Δ24(25)-sterol methyl transferase. J Biol Chem 266:15202-15212
21. Schaeffer A, Bouvier-Navé P, Benveniste P, Schaller H (2000) Plant sterol-C24-methyl transferases: different profiles of tobacco transformed with SMT1 or SMT2. Lipids 35:263-269
22. Schaller H, Grausem B, Benveniste P, Chye M-L, Tan C-T, Chua N-H (1995) Expression of the Hevea brasiliensis (H.B.K.) Mull Arg. 3-hydroxy-3-methylglutaryl-CoA reductase 1 in tobacco results in sterol overproduction. Plant Physiol 109:761-770
23. Schaller H, Bouvier-Nave P, Benveniste P (1998) Overexpression of an Arabidopsis cDNA encoding a sterol-C24-methyl transferase in tobacco modifies the ratio of 24-methylcholesterol to sitosterol and is associated with growth reduction. Plant Physiol 118:461-469
24. Scheid F, Rohmer M, Benveniste P (1982) Biosynthesis of Δ5,23 sterols in etiolated coleoptiles from Zea mays. Phytochemistry 21:1959-1967
25. Sitbon F, Jonsson L (2001) Sterol composition and growth of transgenic tobacco plants expressing type-1 and type-2 sterol methyl transferases. Planta 212:568-572
26. Stermer BA, Bianchini GM, Korth KL (1994) Regulation of HMG-CoA-reductase activity in plants. J Lipid Res 35:1133-1140
27. Yang H, Cromley, D, Wang H, Billheimer, JT, Sturley, SL (1997) Functional expression of a CDNA to human acyl-coenzyme A: cholesterol acyltransferase in yeast. J Biol Chem 272:3980-3985
28. Zimowski J, Wojciechowski ZA (1980a) Acyl donors for sterol esterification by cell-free preparations from Sinapsis alba roots. Phytochemistry 20:1795-1798
29. Zimowski J, Wojciechowski ZA (1980b) Partial purification and specificity of triacyl glycerol:sterol acyltransferase from Sinapsis alba. Phytochemistry 20:1799-1803