메뉴 건너뛰기




Volumn 289, Issue 19, 2003, Pages 2525-2533

Combination Therapy with Hormone Replacement and Alendronate for Prevention of Bone Loss in Elderly Women: A Randomized Controlled Trial

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; CALCIUM; CONJUGATED ESTROGEN; MEDROXYPROGESTERONE; VITAMIN D; MEDROXYPROGESTERONE ACETATE; PROGESTERONE DERIVATIVE;

EID: 0037974904     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.289.19.2525     Document Type: Article
Times cited : (121)

References (41)
  • 1
    • 0037129560 scopus 로고    scopus 로고
    • Epidemiology and outcomes of osteoporotic fractures
    • Cummings SR, Melton LJI. Epidemiology and outcomes of osteoporotic fractures. Lancet. 2002;359:1761-1767.
    • (2002) Lancet , vol.359 , pp. 1761-1767
    • Cummings, S.R.1    Melton, L.J.I.2
  • 2
    • 0007883054 scopus 로고    scopus 로고
    • NIH consensus declares osteoporosis a major public health issue
    • NIH consensus declares osteoporosis a major public health issue. Osteoporosis Rep. 2000;16:1.
    • (2000) Osteoporosis Rep , vol.16 , pp. 1
  • 3
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
    • Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA. 2002;288:321-333.
    • (2002) JAMA , vol.288 , pp. 321-333
  • 4
    • 0033969402 scopus 로고    scopus 로고
    • Bone matters: Are density increases necessary to reduce fracture risk?
    • Faulkner KG. Bone matters: are density increases necessary to reduce fracture risk? J Bone Miner Res. 2000;15:183-187.
    • (2000) J Bone Miner Res , vol.15 , pp. 183-187
    • Faulkner, K.G.1
  • 5
    • 0029986509 scopus 로고    scopus 로고
    • Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures
    • Marshall D, Johnell O, Wedel H. Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ. 1996;312:1254-1259.
    • (1996) BMJ , vol.312 , pp. 1254-1259
    • Marshall, D.1    Johnell, O.2    Wedel, H.3
  • 6
    • 0034456357 scopus 로고    scopus 로고
    • Antifracture efficacy of antiresorptive agents are related to changes in bone density
    • Wasnich RD, Miller PD. Antifracture efficacy of antiresorptive agents are related to changes in bone density. J Clin Endocrinol Metab. 2000;85:231-236.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 231-236
    • Wasnich, R.D.1    Miller, P.D.2
  • 7
    • 0036284616 scopus 로고    scopus 로고
    • Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents
    • Hochberg MC, Greenspan S, Wasnich RD, Miller P, Thompson DE, Ross PD. Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents. J Clin Endocrinol Metab. 2002;87:1586-1592.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1586-1592
    • Hochberg, M.C.1    Greenspan, S.2    Wasnich, R.D.3    Miller, P.4    Thompson, D.E.5    Ross, P.D.6
  • 8
    • 0036119735 scopus 로고    scopus 로고
    • Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with antiresorptive drugs
    • Cummings SR, Karpf DB, Harris F, et al. Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with antiresorptive drugs. Am J Med. 2002;112:281-289.
    • (2002) Am J Med , vol.112 , pp. 281-289
    • Cummings, S.R.1    Karpf, D.B.2    Harris, F.3
  • 9
    • 17744392399 scopus 로고    scopus 로고
    • Alendronate and estrogen effects in postmenopausal women with low bone mineral density
    • Bone HG, Greenspan SL, McKeever C, et al. Alendronate and estrogen effects in postmenopausal women with low bone mineral density. J Clin Endocrinol Metab. 2000;85:720-726.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 720-726
    • Bone, H.G.1    Greenspan, S.L.2    McKeever, C.3
  • 10
    • 0028968710 scopus 로고
    • Prevalence of low femoral bone density in older US women from NHANES III
    • Looker AC, Johnston CC Jr, Wahner HW, et al. Prevalence of low femoral bone density in older US women from NHANES III. J Bone Miner Res. 1995;10:796-802.
    • (1995) J Bone Miner Res , vol.10 , pp. 796-802
    • Looker, A.C.1    Johnston Jr., C.C.2    Wahner, H.W.3
  • 11
    • 0023492504 scopus 로고
    • Dietary calcium intake and bone loss from the spine in healthy postmenopausal women
    • Dawson-Hughes B, Jacques P, Shipp C. Dietary calcium intake and bone loss from the spine in healthy postmenopausal women. Am J Clin Nutr. 1987;46:685-687.
    • (1987) Am J Clin Nutr , vol.46 , pp. 685-687
    • Dawson-Hughes, B.1    Jacques, P.2    Shipp, C.3
  • 14
    • 0029977526 scopus 로고    scopus 로고
    • Classification of osteoporosis in the elderly is dependent on site-specific analysis
    • Greenspan SL, Maitland-Ramsey L, Myers E. Classification of osteoporosis in the elderly is dependent on site-specific analysis. Calcif Tissue Int. 1996;58:409-414.
    • (1996) Calcif Tissue Int , vol.58 , pp. 409-414
    • Greenspan, S.L.1    Maitland-Ramsey, L.2    Myers, E.3
  • 15
    • 15844376474 scopus 로고    scopus 로고
    • Dual X-ray absorptiometry quality control: Comparison of visual examination and process-control charts
    • Lu Y, Mathur AK, Blunt BA, et al. Dual X-ray absorptiometry quality control: comparison of visual examination and process-control charts. J Bone Miner Res. 1996;11:626-637.
    • (1996) J Bone Miner Res , vol.11 , pp. 626-637
    • Lu, Y.1    Mathur, A.K.2    Blunt, B.A.3
  • 16
    • 0014579432 scopus 로고
    • Assessment of older people: Self-maintaining and instrumental activities of daily living
    • Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist. 1969;9:179-186.
    • (1969) Gerontologist , vol.9 , pp. 179-186
    • Lawton, M.P.1    Brody, E.M.2
  • 18
    • 0031689775 scopus 로고    scopus 로고
    • Early changes in biochemical markers of bone turnover predict the longterm response to alendronate therapy in representative elderly women: A randomized clinical trial
    • Greenspan SL, Parker RA, Ferguson L, Rosen HN, Maitland-Ramsey L, Karpf DB. Early changes in biochemical markers of bone turnover predict the longterm response to alendronate therapy in representative elderly women: a randomized clinical trial. J Bone Miner Res. 1998;13:1431-1438.
    • (1998) J Bone Miner Res , vol.13 , pp. 1431-1438
    • Greenspan, S.L.1    Parker, R.A.2    Ferguson, L.3    Rosen, H.N.4    Maitland-Ramsey, L.5    Karpf, D.B.6
  • 19
    • 0034645459 scopus 로고    scopus 로고
    • How many women lose bone mineral density while taking hormone replacement therapy? Results from the Postmenopausal Eastrogen/Progestin Interventions trial
    • Greendale GA, Wells B, Marcus R, Barrett-Connor E, for the Postmenopausal Estrogen/ Progestin Interventions Trial Investigators. How many women lose bone mineral density while taking hormone replacement therapy? results from the Postmenopausal Eastrogen/Progestin Interventions trial. Arch Intern Med. 2000;160:3065-3071.
    • (2000) Arch Intern Med , vol.160 , pp. 3065-3071
    • Greendale, G.A.1    Wells, B.2    Marcus, R.3    Barrett-Connor, E.4
  • 21
    • 0028556527 scopus 로고
    • Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: Synopsis of a WHO report
    • Kanis JA, for the WHO Study Group. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. Osteoporos Int. 1994;4:368-381.
    • (1994) Osteoporos Int , vol.4 , pp. 368-381
    • Kanis, J.A.1
  • 22
    • 77957126077 scopus 로고
    • Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women
    • Writing Group for the PEPI Trial. Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. JAMA. 1995;273:199-208.
    • (1995) JAMA , vol.273 , pp. 199-208
  • 23
    • 0035880311 scopus 로고    scopus 로고
    • Bone mineral density response to estrogen replacement in frail elderly women: A randomized controlled trial
    • Villareal DT, Binder EF, Williams DB, Schechtman KB, Yarasheski KE, Kohrt WM. Bone mineral density response to estrogen replacement in frail elderly women: a randomized controlled trial. JAMA. 2001;286:815-820.
    • (2001) JAMA , vol.286 , pp. 815-820
    • Villareal, D.T.1    Binder, E.F.2    Williams, D.B.3    Schechtman, K.B.4    Yarasheski, K.E.5    Kohrt, W.M.6
  • 24
    • 0004851872 scopus 로고    scopus 로고
    • Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures
    • Black DM, Cummings SR, Karpf DB, et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Lancet. 1996;348:1535-1541.
    • (1996) Lancet , vol.348 , pp. 1535-1541
    • Black, D.M.1    Cummings, S.R.2    Karpf, D.B.3
  • 25
    • 0032583492 scopus 로고    scopus 로고
    • Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: Results from the Fracture Intervention Trial
    • Cummings SR, Black DM, Thompson DE, et al. Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA. 1998;280:2077-2082.
    • (1998) JAMA , vol.280 , pp. 2077-2082
    • Cummings, S.R.1    Black, D.M.2    Thompson, D.E.3
  • 26
    • 0033581212 scopus 로고    scopus 로고
    • Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: Results from a 3-year randomized clinical trial
    • Ettinger B, Black DM, Mitlak BH, et al. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. JAMA. 1999;282:637-645.
    • (1999) JAMA , vol.282 , pp. 637-645
    • Ettinger, B.1    Black, D.M.2    Mitlak, B.H.3
  • 27
    • 0033552255 scopus 로고    scopus 로고
    • Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: A randomized controlled trial
    • Harris ST, Watts NB, Genant HK, et al. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. JAMA. 1999;282:1344-1352.
    • (1999) JAMA , vol.282 , pp. 1344-1352
    • Harris, S.T.1    Watts, N.B.2    Genant, H.K.3
  • 28
    • 12944291524 scopus 로고    scopus 로고
    • Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis
    • Reginster J-Y, Minne HW, Sorensen OH, et al. Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Osteoporos Int. 2000;11:83-91.
    • (2000) Osteoporos Int , vol.11 , pp. 83-91
    • Reginster, J.-Y.1    Minne, H.W.2    Sorensen, O.H.3
  • 29
    • 0036281383 scopus 로고    scopus 로고
    • Effect of estrogen replacement plus low-dose alendronate treatment on bone density in surgically postmenopausal women with osteoporosis
    • Palomba S, Orio FJ, Colao A, et al. Effect of estrogen replacement plus low-dose alendronate treatment on bone density in surgically postmenopausal women with osteoporosis. J Clin Endocrinol Metab. 2002;87:1502-1508.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1502-1508
    • Palomba, S.1    Orio, F.J.2    Colao, A.3
  • 30
    • 0034999663 scopus 로고    scopus 로고
    • Effects of combined risedronate and hormone replacement therapies on bone mineral density in postmenopausal women
    • Harris S, Eriksen EF, Davidson M, et al. Effects of combined risedronate and hormone replacement therapies on bone mineral density in postmenopausal women. J Clin Endocrinol Metab. 2002;86:1890-1897.
    • (2002) J Clin Endocrinol Metab , vol.86 , pp. 1890-1897
    • Harris, S.1    Eriksen, E.F.2    Davidson, M.3
  • 31
    • 0028851590 scopus 로고
    • Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis: The Alendronate Phase III Osteoporosis Treatment Study Group
    • Liberman UA, Weiss SR, Broll J, et al. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis: the Alendronate Phase III Osteoporosis Treatment Study Group. N Engl J Med. 1995;333;1437-1443.
    • (1995) N Engl J Med , vol.333 , pp. 1437-1443
    • Liberman, U.A.1    Weiss, S.R.2    Broll, J.3
  • 32
    • 0032547326 scopus 로고    scopus 로고
    • Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women
    • Hulley S, Grady D, Buch T, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA. 1998;280:605-613.
    • (1998) JAMA , vol.280 , pp. 605-613
    • Hulley, S.1    Grady, D.2    Buch, T.3
  • 33
    • 0029907556 scopus 로고    scopus 로고
    • Effects of hormone therapy on bone mineral density
    • Writing Group for the PEPI Trial. Effects of hormone therapy on bone mineral density. JAMA. 1996;276:1389-1396.
    • (1996) JAMA , vol.276 , pp. 1389-1396
  • 35
    • 0037014630 scopus 로고    scopus 로고
    • Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/Progestin Replacement Study Follow-up (HERS II)
    • Hulley S, Furberg C, Barrett-Connor E, et al. Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/Progestin Replacement Study Follow-up (HERS II). JAMA. 2002;288:58-66.
    • (2002) JAMA , vol.288 , pp. 58-66
    • Hulley, S.1    Furberg, C.2    Barrett-Connor, E.3
  • 36
    • 0037014584 scopus 로고    scopus 로고
    • Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/Progestin Replacement Study Follow-up (HERS II)
    • Grady D, Herrington D, Bittner V, et al. Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/Progestin Replacement Study Follow-up (HERS II). JAMA. 2002;288:49-57.
    • (2002) JAMA , vol.288 , pp. 49-57
    • Grady, D.1    Herrington, D.2    Bittner, V.3
  • 37
    • 0037422848 scopus 로고    scopus 로고
    • Glycemic effects of postmenopausal hormone therapy: The Heart and Estrogen/Progestin Replacement Study: A randomized, double-blind, placebo-controlled trial
    • Kanaya AM, Herrington D, Vittinghoff E, et al. Glycemic effects of postmenopausal hormone therapy: the Heart and Estrogen/Progestin Replacement Study: a randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2003;138:1-9.
    • (2003) Ann Intern Med , vol.138 , pp. 1-9
    • Kanaya, A.M.1    Herrington, D.2    Vittinghoff, E.3
  • 38
    • 0037422841 scopus 로고    scopus 로고
    • Lower diabetes risk with hormone replacement therapy: An encore for estrogen?
    • Wilson PWF. Lower diabetes risk with hormone replacement therapy: an encore for estrogen? Ann Intern Med. 2003;138:69-70.
    • (2003) Ann Intern Med , vol.138 , pp. 69-70
    • Wilson, P.W.F.1
  • 39
    • 0035925762 scopus 로고    scopus 로고
    • Hormone replacement therapy and cognition: A systematic review and meta-analysis
    • LeBlanc ES, Janowsky J, Chan BKS, Nelson HD. Hormone replacement therapy and cognition: a systematic review and meta-analysis. JAMA. 2001;285:1489-1499.
    • (2001) JAMA , vol.285 , pp. 1489-1499
    • LeBlanc, E.S.1    Janowsky, J.2    Chan, B.K.S.3    Nelson, H.D.4
  • 40
    • 0037028766 scopus 로고    scopus 로고
    • Quality-of-life and depressive symptoms in postmenopausal women after receiving hormone therapy: Results from the Heart and Estrogen/Progestin Replacement Study (HERS) trial
    • Hlatky MA, Boothroyd D, Vittinghoff E, Sharp P, Whooley MA, for the HERS Research Group. Quality-of-life and depressive symptoms in postmenopausal women after receiving hormone therapy: results from the Heart and Estrogen/Progestin Replacement Study (HERS) trial. JAMA. 2002;287:591-597.
    • (2002) JAMA , vol.287 , pp. 591-597
    • Hlatky, M.A.1    Boothroyd, D.2    Vittinghoff, E.3    Sharp, P.4    Whooley, M.A.5
  • 41
    • 0035078450 scopus 로고    scopus 로고
    • Can variability in the hormonal status of elderly women assist in the decision to administer estrogens?
    • Kuchel GA, Tannenbaum C, Greenspan SL, Resnick NM. Can variability in the hormonal status of elderly women assist in the decision to administer estrogens? J Womens Health Gender Based Med. 2001;10:109-116.
    • (2001) J Womens Health Gender Based Med , vol.10 , pp. 109-116
    • Kuchel, G.A.1    Tannenbaum, C.2    Greenspan, S.L.3    Resnick, N.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.