Autoimmunity: Busting the atherosclerotic plaque

Nature Medicine

Volumn 9, Issue 6, 2003, Pages 641-642

  Rose, Noel ^a   Afanasyeva, Marina ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CD40 ANTIGEN; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHORYLCHOLINE; PNEUMOCOCCUS VACCINE;

ANGIOGENESIS; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; AUTOIMMUNITY; BACTERIAL INFECTION; HUMAN; IMMUNE RESPONSE; INFLAMMATION; MACROPHAGE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTECTION; PUBLICATION; SHORT SURVEY;

ANIMALS; ANTIGENS, BACTERIAL; ARTERIOSCLEROSIS; AUTOANTIBODIES; AUTOIMMUNITY; EPITOPES; HUMANS; LIPOPROTEINS, LDL; MICE; MOLECULAR MIMICRY; VACCINES;

BACTERIA (MICROORGANISMS);

EID: 0037968382     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0603-641     Document Type: Short Survey

References (9)

1. Stemme, S. et al. T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc. Natl. Acad. Sci. USA 92, 3893-3897 (1995).
2. Wick, G., Perschinka, H. & Millonig, G. Atherosclerosis as an autoimmune disease: an update. Trends Immunol. 22, 665-669 (2001).
3. Binder, C.J. et al. Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nat. Med. 9, 736-743 (2003).
4. Dighiero, G. & Rose, N.R. Critical self-epitopes are key to the understanding of self-tolerance and autoimmunity. Immunol. Today 20, 423-428 (1999).
5. Briles, D.E. et al. Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae. J. Exp. Med. 156, 1177-1185 (1982).
6. Shaw, P.X. et al. Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity. J. Clin. Invest. 105, 1683-1685 (2000).
7. Matsuura, E. et al. Anti-β 2-glycoprotein I autoantibodies and atherosclerosis. Int. Rev. Immunol. 21, 51-66 (2002).
8. Cosenza, H. & Kohler, H. Specific suppression of the antibody response by antibodies to receptors. Proc. Natl. Acad. Sci. USA 69, 2701-2705 (1972).
9. Lieberman, R., Potter, M., Mushinski, E.B., Humphrey, W. Jr. & Rudikoff, S. Genetics of a new IgVH (T15 idiotype) marker in the mouse regulating natural antibody to phosphorylcholine. J. Exp. Med. 139, 983-1001 (1974).