The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: Rescue of activity through reciprocal pro-enzyme activation

Biochemical Journal

Volumn 371, Issue 2, 2003, Pages 277-287

  Behrendt, Niels ^a   List, Karin ^a   Andreasen, Peter A ^b   Danø, Keld ^a  

^a FINSEN LABORATORY   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

2 antiplasmin; Cascade system; Plasminogen activator inhibitor type 1 (PAI 1); Proteolysis; Urokinase type plasminogen activator receptor (uPAR)

Indexed keywords

CHEMICAL REACTIONS; ENZYME INHIBITION; ENZYMES;

ZYMOGENS;

BIOCHEMISTRY;

ALPHA 2 ANTIPLASMIN; ENZYME PRECURSOR; PLASMIN; PLASMINOGEN ACTIVATOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROUROKINASE; SERINE PROTEINASE INHIBITOR; UROKINASE; UROKINASE RECEPTOR;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; COVALENT BOND; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME MECHANISM; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; PLASMINOGEN ACTIVATION; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ENZYME ACTIVATION; ENZYME PRECURSORS; HUMANS; KINETICS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; SERPINS; URINARY PLASMINOGEN ACTIVATOR;

EID: 0037965779     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021508     Document Type: Article

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