Reduction of intestinal neoplasia with adenomatous polyposis coli gene replacement and COX-2 inhibition is additive

Journal of Gastrointestinal Surgery

Volumn 6, Issue 4, 2002, Pages 563-568

  Lew, John I ^a   Guo, Yuee ^a   Kim, Richard K ^a   Vargish, Lisa ^a   Michelassi, Fabrizio ^a   Arenas, Richard B ^b,c,d  

^a UNIVERSITY OF CHICAGO   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MASSACHUSETTS   (United States)

^d BAYSTATE HEALTH   (United States)

Author keywords

Adenomatous polyposis coligene; Colorectal polyps; Cyclooxygenase 2 inhibition; Gene therapy

Indexed keywords

APC PROTEIN; CYCLOOXYGENASE 2 INHIBITOR; LIPOSOME; PLASMID DNA; ROFECOXIB; CYCLOOXYGENASE 2; ISOENZYME; LACTONE; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; SULFONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; COLON POLYPOSIS; COLORECTAL CANCER; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; GENE REPLACEMENT THERAPY; HERPESVIRUS VECTOR; LIPID DIET; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; RANDOMIZATION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING; ANIMAL; COLORECTAL TUMOR; DRUG ANTAGONISM; GENE THERAPY; GENETICS; MULTIMODALITY CANCER THERAPY; TUMOR SUPPRESSOR GENE;

ANIMALS; COLORECTAL NEOPLASMS; COMBINED MODALITY THERAPY; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; GENE THERAPY; GENES, APC; ISOENZYMES; LACTONES; MALE; MICE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SULFONES;

EID: 0037960862     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1091-255X(01)00042-7     Document Type: Article

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