Contribution of cyclic-nucleotide-gated channels to the resting conductance of olfactory receptor neurons

Biophysical Journal

Volumn 84, Issue 5, 2003, Pages 3425-3435

  Pun, Raymund Y K ^a   Kleene, Steven J ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; AMILORIDE; CYCLIC AMP; CYCLIC NUCLEOTIDE; DIVALENT CATION;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DEPOLARIZATION; FROG; NERVE CONDUCTION; NERVE POTENTIAL; NONHUMAN; OLFACTORY RECEPTOR; SENSORY STIMULATION;

ANIMALIA; ANURA;

EID: 0037960324     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(03)70064-2     Document Type: Article

References (48)

1. Bakalyar, H. A., and R. R. Reed. 1990. Identification of a specialized adenylyl cyclase that may mediate odorant detection. Science. 250:1403-1406.
2. Boekhoff, I., E. Tareilus, J. Strotmann, and H. Breer. 1990. Rapid activation of alternative second messenger pathways in olfactory cilia from rats by different odorants. EMBO J. 9:2453-2458.
3. Bönigk, W., J. Bradley, F. Müller, F. Sesti, I. Boekhoff, G. V. Ronnett, U. B. Kaupp, and S. Frings. 1999. The native rat olfactory cyclic nucleotide-gated channel is composed of three distinct subunits. J. Neurosci. 19:5332-5347.
4. Borisy, F. F., G. V. Ronnett, A. M. Cunningham, D. Juilfs, J. Beavo, and S. H. Snyder. 1992. Calcium/calmodulin-activated phosphodiesterase expressed in olfactory receptor neurons. J. Neurosci. 12:915-923.
5. 3-odors." J. Neurophysiol. 84:575-580.
6. 2+-calmodulin of cyclic nucleotide-activated channel of rat olfactory receptor neurons. Nature. 368:545-548.
7. Fenwick, E. M., A. Marty, and E. Neher. 1982. A patch-clamp study of bovine chromaffin cells and of their sensitivity to acetylcholine. J. Physiol. (Lond.). 331:577-597.
8. Firestein, S., B. Darrow, and G. M. Shepherd. 1991a. Activation of the sensory current in salamander olfactory receptor neurons depends on a G protein-mediated cAMP second messenger system. Neuron. 6:825-835.
9. Firestein, S., F. Zufall, and G. M. Shepherd. 1991b. Single odor-sensitive channels in olfactory receptor neurons are also gated by cyclic nucleotides. J. Neurosci. 11:3565-3572.
10. Frings, S., and B. Lindemann. 1998. Odorant response of isolated olfactory receptor cells is blocked by amiloride. J. Membr. Biol. 105:233-243.
11. Frings, S., and B. Lindemann. 1991. Current recording from sensory cilia of olfactory receptor cells in situ. I. The neuronal response to cyclic nucleotides. J. Gen. Physiol. 97:1-16.
12. Frings, S., J. W. Lynch, and B. Lindemann. 1992. Properties of cyclic nucleotide-gated channels mediating olfactory transduction: activation, selectivity and blockage. J. Gen. Physiol. 100:45-67.
13. Guellaen, G., J. L. Mahu, P. Mavier, P. Berthelot, and J. Hanoune. 1977. RMI 12330 A, an inhibitor of adenylate cyclase in rat liver. Biochim. Biophys. Acta. 484:465-475.
14. Horn, R., and A. Marty. 1988. Muscarinic activation of ionic currents measured by a new whole-cell recording method. J. Gen. Physiol. 92:145-159.
15. Kaupp, U. B., and R. Seifert. 2002. Cyclic nucleotide-gated ion channels. Physiol. Rev. 82:769-824.
16. Kleene, S. J. 1993. Origin of the chloride current in olfactory transduction. Neuron. 11:123-132.
17. Kleene, S. J. 1994. Inhibition of olfactory cyclic nucleotide-activated current by calmodulin antagonists. Br. J. Pharmacol. 111:469-472.
18. Kleene, S. J. 1995. Block by external calcium and magnesium of the cyclic-nucleotide-activated current in olfactory cilia. Neuroscience. 66:1001-1008.
19. Kleene, S. J. 1997. High-gain, low-noise amplification in olfactory transduction. Biophys. J. 73:1110-1117.
20. Kleene, S. J. 1999. Both external and internal calcium reduce the sensitivity of the olfactory cyclic nucleotide-gated channel to cAMP. J. Neurophysiol. 81:2675-2682.
21. Kleene, S. J. 2000. Spontaneous gating of olfactory cyclic-nucleotide-gated channels. J. Membr. Biol. 178:49-54.
22. Kleene, S. J., and R. C. Gesteland. 1991. Calcium-activated chloride conductance in frog olfactory cilia. J. Neurosci. 11:3624-3629.
23. Kleene, S. J., and R. Y. K. Pun. 1996. Persistence of the olfactory receptor current in a wide variety of extracellular environments. J. Neurophysiol. 75:1386-1391.
24. Kleinberg, M. E., and A. Finkelstein. 1984. Single-length and doublelength channels formed by nystatin in lipid bilayer membranes. J. Membr. Biol. 80:257-269.
25. Kurahashi, T. 1990. The response induced by intracellular cyclic AMP in isolated olfactory receptor cells of the newt. J. Physiol. (Lond.). 430:355-371.
26. Kurahashi, T., and K. W. Yau. 1993. Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells. Nature. 363:71-74.
27. Leinders-Zufall, T., C. A. Greer, G. M. Shepherd, and F. Zufall. 1998. Imaging odor-induced calcium transients in single olfactory cilia: specificity of activation and role in transduction. J. Neurosci. 18:5630-5639.
28. Lowe, G., and G. H. Gold. 1993. Nonlinear amplification by calcium-dependent chloride channels in olfactory receptor cells. Nature. 366:283-286.
29. Lynch, J. W., and P. H. Barry. 1989. Action potentials initiated by single channels opening in a small neuron (rat olfactory receptor). Biophys. J. 55:755-768.
30. Maguire, M. E., and A. G. Gilman. 1974. Adenylate cyclase assay with adenylyl imidodiphosphate and product detection by competitive protein binding. Biochim. Biophys. Acta. 358:154-163.
31. Marks, P. W., and F. R. Maxfield. 1991. Preparation of solutions with free calcium concentration in the nanomolar range using 1,2-bis(o-aminophenoxy)ethane-N,N,N,N′,N′-tetraacetic acid. Anal. Biochem. 193:61-71.
32. Nakamura, T., and G. H. Gold. 1987. A cyclic nucleotide-gated conductance in olfactory receptor cilia. Nature. 325:442-444.
33. Pace, U., E. Hanski, Y. Salomon, and D. Lancet. 1985. Odorant-sensitive adenylate cyclase may mediate olfactory reception. Nature. 316:255-258.
34. Picones, A., and J. I. Korenbrot. 1995. Spontaneous, ligand-independent activity of the cGMP-gated ion channels in cone photoreceptors of fish. J. Physiol. (Lond.). 485:699-714.
35. Pun, R. Y. K., and R. C. Gesteland. 1991. Somatic sodium channels of frog olfactory receptor neurons are inactivated at rest. Pflügers Arch. 418:504-511.
36. Pun, R. Y. K., S. J. Kleene, and R. C. Gesteland. 1994. Guanine nucleotides modulate steady-state inactivation of voltage-gated sodium channels in frog olfactory receptor neurons. J. Membr. Biol. 142:103-111.
37. Ronnett, G. V., D. J. Parfitt, L. D. Hester, and S. H. Snyder. 1991. Odorantsensitive adenylate cyclase: Rapid, potent activation and desensitization in primary olfactory neuronal cultures. Proc. Natl. Acad. Sci. USA. 88:2366-2369.
38. Ruiz, M. L., and J. W. Karpen. 1997. Single cyclic nucleotide-gated channels locked in different ligand-bound states. Nature. 389:389-392.
39. Schild, D., and D. Restrepo. 1998. Transduction mechanisms in vertebrate olfactory receptor cells. Physiol. Rev. 78:429-466.
40. 2+/calmodulin-dependent protein kinase. J. Cell Biol. 99:11-19.
41. 2+/calmodulin-dependent protein kinase. Adv. Second Messenger Phosphoprotein Res. 22:39-112.
42. Sklar, P. B., R. R. H. Anholt, and S. H. Snyder. 1986. The odorant-sensitive adenylate cyclase of olfactory receptor cells: Differential stimulation by distinct classes of odorants. J. Biol. Chem. 261:15538-15543.
43. Tibbs, G. R., E. H. Goulding, and S. A. Siegelbaum. 1997. Allosteric activation and tuning of ligand efficacy in cyclic-nucleotide-gated channels. Nature. 386:612-615.
44. Wei, J., A. Z. Zhao, G. C. K. Chan, L. P. Baker, S. Impey, J. A. Beavo, and D. R. Storm. 1998. Phosphorylation and inhibition of olfactory adenylyl cyclase by CaM kinase II in neurons: a mechanism for attenuation of olfactory signals. Neuron. 21:495-504.
45. Weiss, J. N. 1997. The Hill equation revisited: uses and misuses. FASEB J. 11:835-841.
46. Yan, C., A. Z. Zhao, J. K. Bentley, K. Loughney, K. Ferguson, and J. A. Beavo. 1995. Molecular cloning and characterization of a calmodulindependent phosphodiesterase enriched in olfactory sensory neurons. Proc. Natl. Acad. Sci. USA. 92:9677-9681.
47. Zagotta, W. N., and S. A. Siegelbaum. 1996. Structure and function of cyclic nucleotide-gated channels. Annu. Rev. Neurosci. 19:235-263.
48. Zufall, F., and S. Firestein. 1993. Divalent cations block the cyclic nucleotide-gated channel of olfactory receptor neurons. J. Neurophysiol. 69:1758-1768.