Restless legs syndrome

New England Journal of Medicine

Volumn 348, Issue 21, 2003, Pages 2103-2109

  Earley, Christopher J ^a  

^a JOHNS HOPKINS BAYVIEW MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; BROMOCRIPTINE; CARBAMAZEPINE; CLONAZEPAM; CODEINE; DEXTROPROPOXYPHENE; DOPAMINE RECEPTOR STIMULATING AGENT; GABAPENTIN; HYDROCODONE; HYPNOTIC SEDATIVE AGENT; IRON; LEVODOPA; METHADONE; MORPHINE SULFATE; OPIATE AGONIST; OXAZEPAM; OXYCODONE; PERGOLIDE; PRAMIPEXOLE; ROPINIROLE; TRAMADOL; TRIAZOLAM; ZALEPLON; ZOLPIDEM; NARCOTIC AGENT;

ADULT; AKATHISIA; ARTICLE; ATAXIA; AUTOSOMAL DOMINANT DISORDER; CASE REPORT; CLINICAL FEATURE; CONSTIPATION; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; DRUG TOLERANCE; FATIGUE; FEMALE; HALLUCINATION; HUMAN; HYPERSOMNIA; INSOMNIA; IRON DEFICIENCY; LEG CRAMP; NAUSEA; NOSE CONGESTION; ORTHOSTATIC HYPOTENSION; PARESTHESIA; POLYSOMNOGRAPHY; PRIORITY JOURNAL; PRURITUS; RESTLESS LEGS SYNDROME; SEDATION; SOMNOLENCE; THORAX PAIN; VERTIGO; VOMITING; XEROSTOMIA; MIDDLE AGED; PRACTICE GUIDELINE; PREGNANCY; PREGNANCY COMPLICATION; REVIEW;

ANTICONVULSANTS; DIAGNOSIS, DIFFERENTIAL; DOPAMINE AGENTS; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; IRON; MIDDLE AGED; NARCOTICS; PRACTICE GUIDELINES; PREGNANCY; PREGNANCY COMPLICATIONS; RESTLESS LEGS SYNDROME;

EID: 0037947320     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMcp021288     Document Type: Article

References (38)

1. Ekbom KA. Restless legs syndrome. Neurology 1960;10:868-73.
2. Allen RP, Earley CJ. Restless legs syndrome: a review of clinical and pathophysiologic features. J Clin Neurophysiol 2001;18:128-47.
3. Idem. Defining the phenotype of the restless legs syndrome (RLS) using age-of-symptom-onset. Sleep Med 2000;1:11-9.
4. Polydefkis M, Allen RP, Hauer P, Earley CJ, Griffin JW, McArthur JC. Subclinical sensory neuropathy in late-onset restless legs syndrome. Neurology 2000;55:1115-21.
5. Desautels A, Turecki G, Montplaisir J, Sequeira A, Verner A, Rouleau GA. Identification of a major susceptibility locus for restless legs syndrome on chromosome 12q. Am J Hum Genet 2001;69:1266-70.
6. Allen RP, Picchietti D, Hening WA, et al. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology: a report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 2003;4:101-19.
7. Coleman RM, Pollak CP, Weitzman ED. Periodic movements in sleep (nocturnal myoclonus): relation to sleep disorders. Ann Neurol 1980;8:416-21.
8. Goodman JD, Brodie C, Ayida GA. Restless leg syndrome in pregnancy. BMJ 1988;297:1101-2.
9. Lee KA, Zaffke ME, Baratte-Beebe K. Restless legs syndrome and sleep disturbance during pregnancy: the role of folate and iron. J Womens Health Gend Based Med 2001;10:335-41.
10. Winkelman JW, Chertow GM, Lazarus JM. Restless legs syndrome in end-stage renal disease. Am J Kidney Dis 1996;28:372-8.
11. Hui DS, Wong TY, Ko FW, et al. Prevalence of sleep disturbances in Chinese patients with end-stage renal failure on continuous ambulatory peritoneal dialysis. Am J Kidney Dis 2000;36:783-8.
12. Rutkove SB, Matheson JK, Logigian EL. Restless legs syndrome in patients with polyneuropathy. Muscle Nerve 1996;19:670-2.
13. O'Keeffe ST, Gavin K, Lavan JN. Iron status and restless legs syndrome in the elderly. Age Ageing 1994;23:200-3.
14. Earley CJ, Allen RP, Beard JL, Connor JR. Insight into the pathophysiology of restless legs syndrome. J Neurosci Res 2000;62:623-8.
15. Cheshire WP Jr. Hypotensive akathisia: autonomic failure associated with leg fidgeting while sitting. Neurology 2000;55:1923-6.
16. Montplaisir J, Nicolas A, Godbout R, Walters A. Restless legs syndrome and periodic limb movement disorder. In: Kryger MH, Roth T, Dement WC, eds. Principles and practice of sleep medicine. 3rd ed. Philadelphia: W.B. Saunders, 2000:742-52.
17. HeningW, Allen R, Earley C, Kushida C, Picchietti D, Silber M. The treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine review. Sleep 1999;22:970-99.
18. Nordlander NB. Therapy in restless legs. Acta Med Scand 1953;145:453-7.
19. O'Keeffe ST, Noel J, Lavan JN. Restless legs syndrome in the elderly. Postgrad Med J 1993;69:701-3.
20. Looker AC, Dallman PR, Carroll MD, Gunter EW, Johnson CL. Prevalence of iron deficiency in the United States. JAMA 1997;277:973-6.
21. Baynes RD. Assessment of iron status. Clin Biochem 1996;29:209-15.
22. Chesson AL Jr, Wise M, Davila D, et al. Practice parameters for the treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine report. Sleep 1999;22:961-8.
23. Wetter TC, Stiasny K, Winkelmann J, et al. A randomized controlled study of pergolide in patients with restless legs syndrome. Neurology 1999;52:944-50.
24. Montplaisir J, Nicolas A, Denesle R, Gomez-Mancilla B. Restless legs syndrome improved by pramipexole: a double-blind randomized trial. Neurology 1999;52:938-43.
25. Eafrey CJ, Allen RP. Pergolide and carbidopa/levodopa treatment of the restless legs syndrome and periodic leg movements in sleep in a consecutive series of patients. Sleep 1996;19:801-10.
26. Lachenmayer L. Parkinson's disease and the ability to drive. J Neurol 2000;247:Suppl 4:IV/28-IV/30.
27. Allen RP, Earley CJ. Augmentation of the restless legs syndrome with carbidopal levodopa. Sleep 1996;19:205-13.
28. Silber MH, Shepard JW Jr, Wisbey JA. Pergolide in the management of restless legs syndrome: an extended study. Sleep 1997;20:878-82.
29. Staedt J, Hunerjager H, Ruther E, Stoppe G. Pergolide: treatment of choice in restless legs syndrome (RLS) and nocturnal myoclonus syndrome (NMS): longterm follow up on pergolide. J Neural Transm 1998;105:265-8.
30. Stiasny K, Wetter TC, Winkelmann J, et al. Long-term effects of pergolide in the treatment of restless legs syndrome. Neurology 2001;56:1399-402.
31. Sun ER, Chen CA, Ho G, Earley CJ, Allen RP. Iron and the restless legs syndrome. Sleep 1998;21:371-7.
32. Davis BJ, Rajput A, Rajput ML, Aul EA, Eichhorn GR. GB-A randomized, double-blind placebo-controlled trial of iron in restless legs syndrome. Eur Neurol 2000;43:70-5.
33. Nordlander NB. Restless legs. Br J Phys Med 1954;17:160-2.
34. Sandyk R, Bernick C, Lee SM, Stern LZ, Iacono RP, Bamford CR. L-dopa in uremic patients with the restless legs syndrome. Int J Neurosci 1987;35:233-5.
35. Trenkwalder C, Stiasny K, Pollmacher T, et al. L-dopa therapy of uremic and idiopathic restless legs syndrome: a double-blind, crossover trial. Sleep 1995;18:681-8.
36. Walker SL, Fine A, Kryger MH. L-DOPAI carbidopa for nocturnal movement disorders in uremia. Sleep 1996;19:214-8.
37. Pieta J, Millar T, Zacharias J, Fine A, Kryger M. Effect of pergolide on restless legs and leg movements in sleep in uremic patients. Sleep 1998;21:617-22.
38. Botez MI, Lambert B. Folate deficiency and restless legs syndrome in pregnancy. N Engl J Med 1977;297:670.