The pathogenesis of atherosclerosis and new opportunities for treatment and prevention

Journal of Neural Transmission, Supplement

Volumn , Issue 63, 2002, Pages 1-17

  Scott, J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; ARYLDIALKYLPHOSPHATASE; CD36 ANTIGEN; CD40 LIGAND; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CXCR2; COLONY STIMULATING FACTOR 1; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GAMMA INTERFERON RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 10; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIDIZED LOW DENSITY LIPOPROTEIN; PADGEM PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; CHOLESTEROL; CYTOKINE; GROWTH PROMOTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; DRUG TARGETING; ENDOTHELIUM CELL; ENVIRONMENTAL FACTOR; HEREDITY; LIPID METABOLISM; LIPID TRANSPORT; LYMPHOCYTE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; RISK FACTOR; TANGIER DISEASE; THROMBOCYTE; VASCULAR SMOOTH MUSCLE; ANIMAL; ARTERIOSCLEROSIS; ARTERY; B LYMPHOCYTE; HUMAN; METABOLISM; PATHOLOGY; T LYMPHOCYTE; VASCULAR ENDOTHELIUM;

ANIMALS; APOLIPOPROTEINS B; ARTERIES; ARTERIOSCLEROSIS; B-LYMPHOCYTES; CHOLESTEROL; CYTOKINES; ENDOTHELIUM, VASCULAR; GROWTH SUBSTANCES; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LIPOPROTEINS, LDL; RISK FACTORS; T-LYMPHOCYTES; TRIGLYCERIDES;

EID: 0037945062     PISSN: 03036995     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-6137-1_1     Document Type: Review

References (10)

1. Aitman TJ (2001) CD36, insulin resistance and coronary heart disease. Lancet 357: 651-652
2. Aitman T, Glazier A, Wallace C, Cooper L, Norsworthy O, Wahid F, Al-Majali K, Trembling P, Mann C, Shoulders C, Graf D, S. Lezin E, Kurtz T, Kren V, Pravenec M, Ibrahimi A, Abumrad N, Stanton L, Scott J (1999) Identification of CD36I (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hyperactive rats. Nature Genet 21: 76-83
3. Glass CK, Witztum JL (2001) Atherosclerosis: the road ahead. Cell 104: 503-516
4. Libby P (2001) Current concepts of the pathogenesis of the acute coronary syndromes. Circulation 104: 365
5. Narcisi YM, Scholtz MC, Scott J, Shoulders CC (1993) Dinucleotide repeat polymorphisms at the lipoprotein lipase (LPL) locus. Hum Genet 92: 312-313
6. Naumova RP, Scott J (2000) The pathogenesis of atherosclerosis. In: Weatherall DJ, Ledingham JGE, Warrell DA (eds) Concise Oxford Textbook of Medicine. Oxford University Press, pp 48-50
7. Ross R (1999) Atherosclerosis - an inflammatory disease. N Engl J Med 340: 115-125
8. Scott J (1995) The pathogenesis of atherosclerosis. Oxford Book of Medicine 2: 2289-2295
9. Scott J (1999) Good cholesterol news. Nature 400: 816-819
10. Stamler J, Wentworth D, Neaton JD (1986) Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT). JAMA 256(20): 2823-2828