Thymidine phosphorylase induces angiogenesis in vivo and in vitro: An evaluation of possible mechanisms

British Journal of Pharmacology

Volumn 139, Issue 2, 2003, Pages 219-231

  Sengupta, Shiladitya ^a,c   Sellers, Lynda A ^a   Matheson, Hugh B ^b   Fan, Tai Ping D ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b TCS CellWorks Ltd   (United Kingdom)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Angiogenesis; Deoxy D Ribose; Haemeoxygenase 1; Thymidine phosphorylase

Indexed keywords

2 DEOXY DEXTRO RIBOSE 1 PHOSPHATE; 2 DEOXYRIBOSE; 6 AMINO 5 CHLOROURACIL; ANGIOGENIC FACTOR; COMPLEMENTARY DNA; HEME OXYGENASE 1; PHOSPHATE; RIBOSE; THYMIDINE PHOSPHORYLASE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CARCINOMA; CANCER CELL CULTURE; CATALYSIS; CELL PROLIFERATION; CONTROLLED STUDY; DNA TRANSFECTION; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOGENESIS; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDUCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TIME; TISSUE REGENERATION; TUMOR VASCULARIZATION; UPREGULATION;

ANGIOGENESIS INDUCING AGENTS; ANIMALS; CELLS, CULTURED; DEOXYRIBOSE; ENDOTHELIUM, VASCULAR; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; NEOVASCULARIZATION, PATHOLOGIC; RIBOSEMONOPHOSPHATES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDINE PHOSPHORYLASE; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037930620     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705216     Document Type: Article

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