Density of organic matrix of native mineralized bone measured by water- and fat-suppressed proton projection MRI

Magnetic Resonance in Medicine

Volumn 50, Issue 1, 2003, Pages 59-68

  Wu, Yaotang ^a,b   Ackerman, Jerome L ^a   Chesler, David A ^a   Graham, Lila ^a   Wang, Yan ^a   Glimcher, Melvin J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Bone matrix; Bone mineralization; Solid state MRI; Water and fat suppression

Indexed keywords

CHEMICAL ANALYSIS; CHEMICAL SHIFT; COLLAGEN; MAGNETIC RESONANCE IMAGING; MAGNETIZATION; MAMMALS;

BONE MATRIX; BONE MINERAL DENSITY; BONE MINERALIZATION; FREE INDUCTION DECAY; MINERALIZED BONE; PROJECTION METHOD; SOLID CONSTITUENTS; WATER AND FAT SUPPRESSION;

MINERALOGY;

COLLAGEN; FAT; WATER;

ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE MATRIX; BONE MINERAL; CATTLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; CORTICAL BONE; DIAPHYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHANTOM; THREE DIMENSIONAL IMAGING; TRABECULAR BONE; WATER FLOW;

EID: 0037925188     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.10512     Document Type: Article

References (41)

1. NIH consensus development panel on osteoporosis prevention, diagnosis, and therapy. JAMA 2001;285:785-795.
2. Meunier PJ, Boivin G. Bone mineral density reflects bone mass but also the degree of mineralization of bone: therapeutic implications. Bone 1997;21:373-377.
3. Riggs BL, Melton LJ. Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density. J Bone Miner Res 2002;17:11-14.
4. Abrahamsen B, Stilgren LS, Hermann AP, Tofteng CL, Barenholdt O, Vestergaard P, Brot C, Nielsen S. Discordance between changes in bone mineral density measured at different skeletal sites in perimenopausal women - implications for assessment of bone loss and response to therapy: the Danish Osteoporosis Prevention Study. J Bone Miner Res 2002;16:1212-1219.
5. Nielsen SP. The fallacy of BMD: a critical review of the diagnostic use of dual x-ray absorptiometry. Clin Rheumatol 2000;19:174-183.
6. Sarkar S, Mitlak BH, Wong M, Stock JL, Black DM, Harper KD. Relationships between bone mineral density and incident vertebral fracture risk with raloxifene therapy. J Bone Miner Res 2002;17:1-10.
7. Sartoris DJ. Quantitative bone mineral analysis. In: Resnick D, editor. Bone and joint imaging. Philadelphia: WB Saunders; 1996, p 154.
8. Pitt MJ. Rickets and osteomalacia. In: Resnick D, editor. Bone and joint imaging. Philadelphia: WB Saunders; 1996. p 511.
9. Kaufman J, Batal J, Figueiredo M, Nasser P, Mont M, Pilla A, Siffert R. Vertebral CT image segmentation for trabecular architecture assessment. Proc Orthop Res Soc 1990;36:260.
10. Mundinger A, Wiesmeier B, Dinkel E, Helwig A, Beck A, Schulte-Moenting J. Quantitative image analysis of vertebral body architecture - improved diagnosis in osteoporosis based on high-resolution computed tomography. Osteoporos Int 1993;3:138-147.
11. Laib A, Hildebrand T, Hauselmann HJ, Rüegsegger P. Ridge number density: a new parameter for in vivo bone structure analysis. Bone 1997;21:541-546.
12. Newitt DC, van Rietbergen B, Majumdar S. Processing and analysis of in vivo high-resolution MR images of trabecular bone for longitudinal studies: reproducibility of structural measures and micro-finite element analysis derived mechanical properties. Osteoporos Int 2002;13: 278-287.
13. Takahashi M, Wehrli FW, Hilaire L, Zemel B, Hwang, SN. In vivo NMR microscopy allows short-term serial assessment of multiple skeletal implications of corticosteroid exposure. Proc Natl Acad Sci USA 2002; 99:4574-4579.
14. Foo T, Shellock F, Hayes C, Schenck J, Slayman B. High-resolution MR imaging of the wrist and eye with short TR, short TE and partial-echo acquisition. Radiology 1992;183:277-281.
15. 31P NMR of solid calcium phosphates. J Am Chem Soc 1980; 10:2637-2643.
16. Aue WP, Roufosse AH, Glimcher MJ, Griffin RG. Solid-state phosphorus-31 nuclear magnetic resonance studies of synthetic solid phases of calcium phosphate: potential models of bone mineral. Biochemistry 1984:23:6110-6114.
17. 31P NMR spectroscopy of bone and bone substitutes. Magn Reson Med 1992:28:1-8.
18. 31P hetcor experiments on bone, bone mineral and model calcium phosphate phases. J Magn Reson B 1994;105:183-187.
19. Wu Y, Glimcher MJ, Rey C, Ackerman JL. A unique protonated phosphate group in bone mineral not present in synthetic calcium phosphates: identification by phosphorus-31 solid state NMR spectroscopy. J Mol Biol 1994;244:423-435.
20. Wu Y, Ackerman JL, Rev C. Glimcher MJ. Nuclear magnetic resonance spin-spin relaxation of bone mineral crystals. J Bone Miner Res 2002; 17:472-480.
21. Cho G, Wu Y, Ackerman JL. Detection of hydroxl ions in bone mineral by solid-state NMR spectroscopy. Science 2003;300:1123-1127.
22. 31P solid state NMR spectroscopy at early stages of mineralization. Calcif Tissue Int, in press.
23. 31P NMR imaging of solid bone with solid echoes combined with refocused gradients. Phys Med Biol 1990;35:1153-1158.
24. Wu Y, Ackerman JL, Chester DA, Li J, Neer RM, Wang J, Glimcher MJ. Evaluation of bone mineral density using three dimensional solid state phosphrus-31 NMR projection imaging. Calcif Tissue Int 1998;62:512-518.
25. Wu Y, Chesler DA, Glimcher ML, Garrido L, Wang J, Jiang HJ, Ackerman JL. Multinuclear solid state three dimensional MRI of bone and synthetic calcium phosphates. Proc Natl Acad Sci USA 1999:96:1574-1578.
26. Ramanathan C, Ackerman JL. Quantitative solid state NMR imaging of synthetic calcium phosphate implants. Magn Reson Med 1999;41: 1214-1220.
27. 2* rigid biological tissues. In: Proc 7th Annual Meeting ISMRM, Philadelphia, 1999. p 265.
28. Gillies DG, Newliug B, Randall EW. Phosphorus-31 solid-state NMR in high-field gradients: prospects for imaging bone using the long echotrain summation technique (LETS). J Magn Reson 2001;151:235-241.
29. Fernández-Seara MA, Wehrli SL, Wehrli FW. Multipoint mapping for imaging of semi-solid materials. J Magn Reson 2003;160:144-150.
30. Wu Y, Ackerman JL, Chesler DA, Graham L, Glimcher MJ. Bone matrix density measured by water- and fat-suppressed solids state proton MRI (Abstract). In: Proc 10th Annual Meeting ISMRM, Honolulu, 2002. p 255.
31. Dixon WT. Simple proton spectroscopic imaging. Radiology 1984;153: 189-194.
32. Keller PJ, Hunter WW Jr, Schmalbrock P. Multisection fat-water imaging with chemical shift selective presaturation. Radiology 1987;164: 539-541.
33. Fleckenstein JL, Archer BT, Barker BA, Vaughan JT, Parkey RW, Peshock RM. Fast short-tau inversion-recovery MR imaging. Radiology 1991;79:499-504.
34. Zee CS, Segall HD, Terk MR, Destian S, Ahmadi J, Gober JR, Colletti PM. Spiral MRI in spinal disease. J Comput Assist Tomogr 1992;16: 356-360.
35. Price WS, Water signal suppression in NMR spectroscopy. Ann Report NMR Spectrosc 1999;38:289-354.
36. 2 imaging. J Magn Reson 1984;134:134-152.
37. Torrey HC. Transient nutations in nuclear magnetic resonance. Phys Rev 1949;76:1059-1068.
38. 2-selective RF excitation (TELEX) pulses. Magn Reson Med 1998;40:890-899.
39. 2 species. In: Proc 11th SMRM, Berlin, 1992. p 665.
40. Amano Y, Kumazaki T. Quantitative and qualitative assessment of reactive hematopoietic bone marrow in aplastic anemia using MR spectroscopy with variable echo times. Skeletal Radiol 2002;31:19-24.
41. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 1987;2:595-610.