Decreased binding of peptides-MHC class I (pMHC) multimeric complexes to CD8 affects their binding avidity for the TCR but does not significantly impact on pMHC/TCR dissociation rate

Journal of Immunology

Volumn 170, Issue 10, 2003, Pages 5110-5117

  Dutoit, Valérie ^a,b   Guillaume, Philippe ^c   Ayyoub, Maha ^a,b   Hesdorffer, Charles S ^b   Luescher, Immanuel F ^c   Valmori, Danila ^a,b,d  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b Columbia Univ Coll of Phys/Surgs ^*  (United States)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d Hopital Orthopedique de la Suisse Romande   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; T LYMPHOCYTE RECEPTOR;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL FUNCTION; CELL MATURATION; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; LYMPHOCYTE CLONE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; T LYMPHOCYTE ACTIVATION; THYMUS;

EID: 0037884764     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.10.5110     Document Type: Article

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