The R271W mutant form of Pit-1 does not act as a dominant inhibitor of Pit-1 action to activate the promoters of GH and prolactin genes

European Journal of Endocrinology

Volumn 148, Issue 6, 2003, Pages 619-625

  Kishimoto, Masahiko ^a   Okimura, Yasuhiko ^a   Fumoto, Mariko ^a   Iguchi, Genzo ^a   Iida, Keiji ^a   Kaji, Hidesuke ^b   Chihara, Kazuo ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Dept of Physiology and Biochemistry   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; DNA; GROWTH HORMONE; HYPOPHYSIS HORMONE; LUCIFERASE; PROLACTIN; THYROTROPIN; TRANSCRIPTION FACTOR PIT 1; TRYPTOPHAN;

ALLELE; ANIMAL CELL; ARTICLE; CELL STRAIN COS7; CHO CELL; CODON; CONTROLLED STUDY; DNA FLANKING REGION; DNA RESPONSIVE ELEMENT; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE INSERTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GROWTH HORMONE DEFICIENCY; HETEROZYGOTE; HORMONE DEFICIENCY; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; RAT; REPORTER GENE; WILD TYPE;

ANIMALS; CALCIUM PHOSPHATES; CELL NUCLEUS; CHO CELLS; COS CELLS; CRICETINAE; DNA-BINDING PROTEINS; GENES, REPORTER; HUMAN GROWTH HORMONE; HUMANS; LUCIFERASES; MUTAGENESIS; PITUITARY DISEASES; POINT MUTATION; PROLACTIN; PROMOTER REGIONS (GENETICS); TRANSCRIPTION FACTOR PIT-1; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0037868325     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1480619     Document Type: Article

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