Increased expression of 5-lipoxygenase in glioblastoma multiforme

Advances in Experimental Medicine and Biology

Volumn 525, Issue , 2003, Pages 205-208

  Golubic, Mladen ^a   Prayson, Richard A ^a   Vargo, Linda ^a   Bondar, Judy ^a   Barnett, Gene H ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ARACHIDONATE 5 LIPOXYGENASE; MESSENGER RNA;

BRAIN TISSUE; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOPLASM; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MACROPHAGE MIGRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TUMOR NECROSIS;

EID: 0037867777     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-9194-2_44     Document Type: Conference Paper

References (22)

1. Maher EA, Furnari FB, Bachoo RM, Rowitch DH, Louis DN, Caveene WK, DePinho RA: Malignant glioma: genetics and biology of grave matter. Gen Develop, 2001; 15:1311-1333.
2. Ledwozyw A, Lutnicki K: Phospholipids and fatty acids in human brain tumors. Acta Physiol Hungarica 1992; 79:381-387.
3. Kokoglu E, Tuter Y, Yazici Z, Sandicki KS, Sonmez H, Ulakoglu EZ, Ozyurt E: Profiles of the fatty acids in the plasma membrane of human brain tumors. Cancer Biochem Biophys 1998; 16:301-312.
4. Shono T, Tofilon PJ, Bruner JM, Owolabi O, Lang FF: Cyclooxygenase-2 expression in human gliomas: Prognostic significance and molecular correlations. Cancer Res 2001; 61:4375-4381.
5. Simmet T, Luck W, Winking M, Delank WK, Peskar BA: Identification and characterization of eysteinyl-leukotriene formation in tissue slices from human intracranial tumors: evidence for their biosynthesis under in vivo conditions. J Neurochem 1990; 54:2091-2099.
6. Castelli MG, Chiabrando C, Fanelli R, Martelli L, Butti G, Geatani P, Paoletti P: Prostaglandin and thromboxane synthesis by human intracranial tumors. Cancer Res 1989; 49:1505-1058.
7. Funk CD: Prostaglandins and Leukotrienes: Advances in eicosanoid biology. Science 2001; 294:1871-1875.
8. Romano M, Catalano A, Nutini M, D'Urbano E, Crescenzi C, Claria J, Libner R, Davi G Procopio A: 5-Lipoxygenase regulates malignant mesothelioma cell survival: involvement of vascular endothelial growth factor. FASEB J 2001; 15:2326-2336.
9. Tong W-g, Ding X-Z, Witt RC, Adrian TE: Lipoxygenase inhibitors attenuate growth of human pancreatic cancer xenografts and induce apoptosis through the mitochondrial pathway. Mol Cancer Therap 2002; 1:929-935.
10. Boado RJ, Pardridge WM, Vinters HV, Black KL: Differential expression of arachidonate 5-lipoxygenase transcripts in human brain tumors: Evidence for the expression of a multitranscript family. Proc Natl Acad Sci USA 1992; 89:9044-9048.
11. Gupta S, Srivastava M, Ahmad N, Sakamoto K, Bostwick DG, Mukhtar H: Lipoxygenase-5 is overexpressed in prostate adenocarcinoma. Cancer 2000; 91:737-743.
12. Woods JW, Evans JF, Ethier D, Scott S, Vickers PH, Hearn L, Heibein JA, Charleson S, Dinger II: 5-lipoxygenase and 5-lipoxygenase -activating protein are localized in the nuclear envelope of activated human leukocytes. J Exp Med 1993; 178:1935-1946.
13. Steele VE, Holmes CA, Hawk ET, Kopelovich L, Lubet RA, Crowell JA, Sigman CC, Kelloff GJ: Lipoxygenase inhibitors as potential cancer chemopreventives. Cancer Epidemiol Biomarkers Prev 1999; 8:467-483.
14. Safayhi H, Mack T, Sabieraj J, Anazodo MI, Subramanian LR, Ammon HP: Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. J Pharmacol Exper Therap 1992; 261:1143-1146.
15. Hong SH, Avis I, Vos MD, Martinez A, Treston AM, Mulshine JL: Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors. Cancer Res 1999; 59:2223-2228.
16. Park YS, Lee JH, Bondar J, Harwalker JA, Safayhi H, and Golubic M: Cytotoxic action of acetyl-11-keto-β-boswellic acid (AKBA) on meningioma cells. Planta Medica 2002; 68:397-401.
17. Glaser T, Winter S, Groscurth P, et al: Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity. Br J Cancer 1999; 80:756-765.
18. Park YS, Lee JH, Barnett GH, Bondar J, Harwalkar JA, Safayhi H, Golubic M: Frankincense-derived boswellic acids inhibit growth and motility of brain tumor cells. Complementary Therapies Med 2002; 10:117-118.
19. Winking M, Sarikaya S, Rahmanian A, Jodicke A, Boker DK: Boswellic acids inhibit glioma growth: a new treatment option? J Neurooncol 2000;46: 97-103.
20. Avis IM, Jett M, Boyle T, Vos MD, Moody T, Treston AM, Martinez A, Mulshine JL: Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling. J Clin Invest 1996; 97:806-813.
21. Hennig R, Ding X-Z, Tong W-G, Schneider MB, Standop J, Friess H, Buchler MW, Pour PM, Adrian TE: 5-Lipoxygenase and Leukotriene B4 receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissue. Am J Pathol 2002; 161:421-428.
22. Nielsen CK, Ohd JF, Sjolander A: The leukotriene receptor CysLT1 and 5-lipoxygenase are upregulated in colon cancer. In Advances in Prostaglandin, Leukotriene and Other Bioactive Lipid Research: Basic Science and Clinical Applicaions, 2003, Kluwer Academic Plenum Publishers, New York (in press).