Biochemical antioxidant levels respond to supplementation with an enriched drink in frail elderly people

Journal of the American College of Nutrition

Volumn 22, Issue 3, 2003, Pages 232-238

  Wouters Wesseling, Wendeline ^a   Wagenaar, Lisette W ^a   de Groot, Lisette C P G M ^b   Bindels, Jacques G ^a,b   van Staveren, Wija A ^b  

^a NUMICO RESEARCH   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Antioxidant; Elderly people; Nutrition; Supplementation

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CYSTEINE; GLUTATHIONE PEROXIDASE; PLACEBO; THIOL; URIC ACID;

AGED; ANTIOXIDANT ACTIVITY; ARTICLE; BEVERAGE; BODY MASS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; ELDERLY CARE; ENZYME ASSAY; ERYTHROCYTE LEVEL; FEEDING BEHAVIOR; FEMALE; FOOD INTAKE; HOUSING; HUMAN; MAJOR CLINICAL STUDY; MALE; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME; VITAMIN BLOOD LEVEL; VITAMIN INTAKE;

AGED; ANTIOXIDANTS; ASCORBIC ACID; BEVERAGES; BODY MASS INDEX; CYSTEINE; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; ERYTHROCYTES; FRAIL ELDERLY; GLUTATHIONE PEROXIDASE; HUMANS; MINERALS; NUTRITION POLICY; PLACEBOS; REFERENCE VALUES; VITAMIN E; VITAMINS;

EID: 0037866387     PISSN: 07315724     EISSN: 15411087     Source Type: Journal    
DOI: 10.1080/07315724.2003.10719298     Document Type: Article

References (46)

1. Harman D: Free radical theory of aging: the "free radical" diseases. Age 7:111-131, 1984.
2. Block G, Patterson B, Subar A: Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 18:1-29, 1992.
3. Stampfer MJ, Rimm EB: Epidemiologic evidence for vitamin E in prevention of cardiovascular disease. Am J Clin Nutr 62: 1365S-1369S, 1995.
4. Kohlmeier L, Hastings SB: Epidemiologic evidence of a role of carotenoids in cardiovascular disease prevention. Am J Clin Nutr 62:1370S-1376S, 1995.
5. Stampfer MJ, Rimm B: A review of the epidemiology of dietary antioxidants and risk of coronary heart disease. Can J Cardiol 9:14B-18B, 1993.
6. Cotgreave IA, Gerdes RG: Recent trends in glutathione biochemistry- glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation? Biochem Biophys Res Commun 242:1-9, 1998.
7. Wright AJ, Southon S, Bailey AL, Finglas PM, Maisey S, Fulcher RA: Nutrient intake and biochemical status of non-instutionalized elderly subjects in Norwich: comparison with younger adults and adolescents from the same general community. Br J Nutr 74:453-475, 1995.
8. Campbell D, Bunker VW, Thomas AJ, Clayton BE: Selenium and vitamin E status of healthy and institutionalized elderly subjects: analysis of plasma, erythrocytes and platelets. Br J Nutr 62:221-227, 1989.
9. Asciutti-Moura LS, Guilland J-C, Fuchs F, Richard D: Vitamins E, C, thiamin, riboflavin and vitamin B6 status of institutionalized elderly including the effects of supplementation. Nutr Res 13: 1379-1392, 1993.
10. Bortoli A, Fazzin G, Marchiori M, Mello F, Brugiolo R, Martelli F: Selenium status and effect of selenium supplementation in a group of elderly women. J Trace Elem Electrolytes Health Dis 5:19-21, 1991.
11. Bates CJ, Thane CW, Prentice A, Delves HT: Selenium status and its correlates in a British national diet and nutrition survey: people aged 65 years and over. J Trace Elem Med Biol 16:1-8, 2002.
12. King CM, Bristow-Craig HE, Gillespie ES, Barnett YA: In vivo antioxidant status, DNA damage, mutation and DNA repair capacity in cultured lymphocytes from healthy 75- to 80-year-old humans. Mutat Res 377:137-147, 1997.
13. Cristol JP, Abderrazick M, Favier F, Michel F, Castel J, Leger C, Descomps B: Impairment of antioxidant defense mechanisms in elderly women without increase in oxidative stress markers: "a weak equilibrium." Lipids 34:S289, 1999.
14. Cals MJ, Succari M, Meneguzzer E, Ponteziere C, Bories PN, Devanlay M, Desveaux N, Gatey M: Markers of oxidative stress in fit, health-conscious elderly people living in the Paris area. The Research Group on Ageing (GERBAP). Nutrition 13:319-326, 1997.
15. Guemouri L, Artur Y, Herbeth B, Jeandel C, Cuny G, Siest G: Biological variability of superoxide dismutase, glutathione peroxidase, and catalase in blood. Clin Chem 37:1932-1937, 1991.
16. Kasapoglu M, Ozben T: Alterations of antioxidant enzymes and oxidative stress markers in aging. Exp Gerontol 36:209-220, 2001.
17. Schmuck A, Roussel AM, Arnaud J, Ducros V, Favier A, Franco A: Analyzed dietary intakes, plasma concentrations of zinc, copper, and selenium, and related antioxidant enzyme activities in hospitalized elderly women. J Am Coll Nutr 15:462-468, 1996.
18. Congy F, Bonnefont-Rousselot D, Dever S, Delattre J, Emerit J: Study of oxidative stress in the elderly [French]. Presse Med 24:1115-1118, 1995.
19. Hernanz A, Fernandez-Vivancos E, Montiel C, Vazquez JJ, Arnalich F: Changes in the intracellular homocysteine and glutathione content associated with aging. Life Sci 67:1317-1324, 2000.
20. Nuttall SL, Martin U, Sinclair AJ, Kendall MJ: Glutathione: in sickness and in health. Lancet 351:645-646, 1998.
21. Julius M, Lang CA, Gleiberman L, Harburg E, DiFranceisco W, Schork A: Glutathione and morbidity in a community-based sample of elderly. J Clin Epidemiol 47:1021-1026, 1994.
22. Mann BA, Garry PJ, Hunt WC, Owen GM, Goodwin JS: Daily multivitamin supplementation and vitamin blood levels in the elderly: a randomized, double-blind, placebo-controlled trial. J Am Geriatr Soc 35:302-306, 1987.
23. Clausen J, Nielsen SA, Kristensen M: Biochemical and clinical effects of an antioxidative supplementation of geriatric patients. Biol Trace Elem Res 20:135-150, 1989.
24. Birlouez-Aragon I, Girard F, Ravelontseheno L, Bourgeois C, Belliot JP, Abitbol G: Comparison of two levels of vitamin C supplementation on antioxidant vitamin status in elderly institutionalised subjects. Internat J Vit Nutr Res 65:261-266, 1995.
25. Galan P, Preziosi P, Monget AL, Richard MJ, Arnaud J, Lesourd B, Girodon F, Alferez MJ, Bourgeois C, Keller H, Favier A, Hercberg S: Effects of trace element and/or vitamin supplementation on vitamin and mineral status, free radical metabolism and immunological markers in elderly long term-hospitalized subjects. Geriatric Network MIN. VIT. AOX. Int J Vitam Nutr Res 67:450-460, 1997.
26. McKay DL, Perrone G, Rasmussen H, Dallal G, Hartman W, Cao G, Prior RL, Roubenoff R, Blumberg JB: The effects of a multivitamin/mineral supplement on micronutrient status, antioxidant capacity and cytokine production in healthy older adults consuming a fortified diet. J Am Coll Nutr 19:613-621, 2000.
27. Berkhout AM, Cools HJ, Mulder JD: Measurement or estimation of body length in older nursing home patients [Dutch]. Tijdschr Gerontol Geriatr 20:211-214, 1989.
28. de Jong N, Chin A, Paw MJ, de Graaf C, van Staveren WA: Effect of dietary supplements and physical exercise on sensory perception, appetite, dietary intake and body weight in frail elderly subjects. Br J Nutr 83:605-613, 2000.
29. Voedingsstoffenbestand SN: Dutch Nutrient Data Base/Nederlandse Voedingsmiddelentabel. The Hague: Voorlichtingsbureau voor de Voeding, 1997.
30. Daskalakis I, Lucock MD, Anderson A, Wild J, Schorah CJ, Levene MI: Determination of plasma total homocysteine and cysteine using HPLC with fluorescence detection and an ammonium 7-fluoro-2, 1, 3- benzoxadiazole-4-sulphonate (SBD-F) derivatization protocol optimized for antioxidant concentration, derivatization reagent concentration, temperature and matrix pH. Biomed Chromatogr 10:205-212, 1996.
31. Stump DD: Simultaneous determination by high-performance liquid chromatography of tocopherol isomers, alpha-tocopherol quinone, and cholesterol in red blood cells and plasma. J Chrom 306:377-382, 1984.
32. Liau LS, Lee BL, New AL, Ong CN: Determination of plasma ascorbic acid by high-performance liquid chromatography with ultraviolet and electrochemical detection. J Chromatogr 612:63-70, 1993.
33. Motchnik PA, Frei B, Ames BN: Measurement of antioxidants in human blood plasma. Methods Enzymol 234:269-279, 1994.
34. Margolis SA, Duewer DL: Measurement of ascorbic acid in human plasma and serum: stability, intralaboratory repeatability, and interlaboratory reproducibility. Clinical Chemistry 42:1257-1262, 1996.
35. Beutler E: "Red Cell Metabolism. A Manual of Biochemical Methods." New York: Grune & Stratton, pp 112-114, 1975.
36. Belsten JL, Wright AJ: European Community-FLAIR common assay for whole-blood glutathione peroxidase (GSH-Px); results of an inter-laboratory trial. Eur J Clin Nutr 49:921-927, 1995.
37. Riggs A: Preparation of blood hemoglobins of vertebrates. Methods Enzymol 76:5-29, 1981.
38. Arts MJTJ, Haenen GRMM, Wilms LC, Beetstra SAJN, Heijnen CGM, Voss HP, Bast A: Interactions between flavonoids and proteins: effect on the total antioxidant capacity. J Agric Food Chem 50:1184-1187, 2002.
39. Gritschneder K, Herbert B, Luhrmann P, Neuhauser-Berthold M: Nutritional status of participants in the Giessen Senior Long-Term Study with respect to antioxidant vitamins and selenium [German]. Z Gerontol Geriat 31:448-453, 1998.
40. Armstrong D, Browne R: The analysis of free radicals, lipid peroxides, antioxidant enzymes and compounds related to oxidative stress as applied to the clinical chemistry laboratory. Adv Exp Med Bio 366:43-58, 1994.
41. Bunker VW: Free radicals, antioxidants and ageing. Med Lab Sci 49:299-312, 1992.
42. Rowe B, Kudsk K, Borum P, Madsen D: Effects of whey- and casein-based diets on glutathione and cysteine metabolism in ICU patients. Am J Clin Nutr 13:535, 1994.
43. Michels M, Micke P, Beeh KM, Schlaak JF, Buhl R: A randomized controlled trial of the effect of oral supplementation with whey proteins on plasma glutathione levels of HIV infected patients. Clin Nutr 19:11-12, 2000.
44. Meydani M: Dietary antioxidants modulation of aging and immune- endothelial cell interaction. Mech Ageing Dev 111:123-132, 1999.
45. Perrig WJ, Perrig P, Stahelin HB: The relation between antioxidants and memory performance in the old and very old. J Am Geriatr Soc 45:718-724, 1997.
46. Wouters-Wesseling W, Rozendaal M, Snijder M, Graus Y, Rimmelzwaan G, de Groot L, Bindels J: Effect of a complete nutritional supplement on antibody response to influenza vaccine in the elderly. J Gerontol Med Sci 57:563-566, 2002.