Transgene expression of green fluorescent protein and germ line transmission in cloned calves derived from in vitro-transfected somatic cells

Biology of Reproduction

Volumn 68, Issue 6, 2003, Pages 2013-2023

  Bordignon, Vilceu ^a   Keyston, Rebecca ^b   Lazaris, Anthoula ^b   Bilodeau, Annie S ^b   Pontes, José H F ^a   Arnold, Daniel ^a   Fecteau, Gilles ^a   Keefer, Carol ^b   Smith, Lawrence C ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Nexia Biotechnologies Inc   (Canada)

Author keywords

Assisted reproductive technology; Embryo; Gene regulation; In vitro fertilization; Sperm

Indexed keywords

GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ARTICLE; BLASTOCYST; CATTLE; CELL DIFFERENTIATION; CELL NUCLEUS TRANSPLANTATION; CELL SYNCHRONIZATION; CLONING; CONTROLLED STUDY; FIBROBLAST; GENE SILENCING; GENETIC TRANSFECTION; GERM LINE; IN SITU HYBRIDIZATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPORTER GENE; SPERM; TRANSGENIC ANIMAL;

ANIMALS; CATTLE; CELL LINE; CELL NUCLEUS; CELLS, CULTURED; CLONING, ORGANISM; EMBRYO; EMBRYO TRANSFER; FEMALE; FIBROBLASTS; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GERM CELLS; GREEN FLUORESCENT PROTEINS; IN SITU HYBRIDIZATION, FLUORESCENCE; LUMINESCENT PROTEINS; METAPHASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TELOPHASE; TRANSFECTION; TRANSGENES;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0037837118     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.102.010066     Document Type: Article

References (51)

1. Palmiter RD, Brinster RL, Hammer RE, Trumbauer ME, Rosenfeld MG, Birnberg NC, Evans RM. Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature 1982; 300:611-615.
2. Hammer RE, Pursel VG, Rexroad CE Jr, Wall RJ, Bolt DJ, Ebert KM, Palmiter RD, Brinster RL. Production of transgenic rabbits, sheep and pigs by microinjection. Nature 1985; 315:680-683.
3. Bowen RA, Reed ML, Schnieke A, Seidel GEJ, Stacey A, Thomas WK, Kajikawa O. Transgenic cattle resulting from biopsied embryos: expression of c-ski in a transgenic calf. Biol Reprod 1994; 50:664-668.
4. Wilmut I, Schnleke AE, McWhir J, Kind AJ, Campbell KHS. Viable offspring derived from fetal and adult mammalian cells. Nature 1997; 385:810-813.
5. Wakayama T, Perry AC, Zuccotti M, Johnson KR, Yanagimachi R. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 1998; 394:369-374.
6. Kato Y, Tani T, Tsunoda Y. Cloning of calves from various somatic cell types of male and female adult, newborn and fetal cows. J Reprod Fertil 2000; 120:231-237.
7. Cibelli JB, Stice SL, Golueke PJ, Kane JJ, Jerry J, Blackwell C, Ponce dLF, Robl JM. Cloned transgenic calves produced from nonquiescent fetal fibroblasts. Science 1998; 280:1256-1258.
8. Zakhartchenko V, Mueller S, Alberio R, Schernthaner W, Stojkovic M, Wenigerkind H, Wanke R, Lassnig C, Mueller M, Wolf E, Brem G. Nuclear transfer in cattle with non-transfected and transfected fetal or cloned transgenic fetal and postnatal fibroblasts. Mol Reprod Dev 2001; 60:362-369.
9. Schnieke AE, Kind AJ, Ritchie WA, Mycock K, Scott AR, Ritchie M, Wilmut I, Colman A, Campbell KH. Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts. Science 1997; 278:2130-2133.
10. McCreath KJ, Howcroft J, Campbell KH, Colman A, Schnieke AE, Kind AJ. Production of gene-targeted sheep by nuclear transfer from cultured somatic cells. Nature 2000; 405:1066-1069.
11. Baguisi A, Behboodi E, Melican DT, Pollock JS, Destrempes MM, Cammuso C, Williams JL, Nims SD, Porter CA, Midura P, Palacios MJ, Ayres SL, Denniston RS, Hayes ML, Ziomek CA, Meade HM, Godke RA, Gavin WG, Overstrom EW, Echelard Y. Production of goats by somatic cell nuclear transfer. Nat Biotechnol 1999; 17:456-461.
12. Keefer CL, Baldassarre H, Keyston R, Wang B, Bhatia B, Bilodeau AS, Zhou JF, Leduc M, Downey BR, Lazaris A, Karatzas CN. Generation of dwarf goat (Capra hircus) clones following nuclear transfer with transfected and nontransfected fetal fibroblasts and in vitro-matured oocytes. Biol Reprod 2001; 64:849-856.
13. Reggio BC, James AN, Green HL, Gavin WG, Behboodi E, Echelard Y, Godke RA. Cloned transgenic offspring resulting from somatic cell nuclear transfer in the goat: oocytes derived from both follicle-stimulating hormone-stimulated and nonstimulated abattoir-derived ovaries. Biol Reprod 2001; 65:1528-1533.
14. Bondioli K, Ramsoondar J, Williams B, Costa C, Fodor W. Cloned pigs generated from cultured skin fibroblasts derived from a H-transferase transgenic boar. Mol Reprod Dev 2001; 60:189-195.
15. Park KW, Lai L, Cheong HT, Cabot R, Sun QY, Wu G, Rucker EB, Durtschi D, Bonk A, Samuel M, Rieke A, Day BN, Murphy CN, Carter DB, Prather RS. Mosaic gene expression in nuclear transferderived embryos and the production of cloned transgenic pigs from ear-derived fibroblasts. Biol Reprod 2002; 66:1001-1005.
16. Renard JP, Zhou Q, Lebourhis D, Chavatte-Palmer P, Hue I, Heyman Y, Vignon X. Nuclear transfer technologies: between successes and doubts. Theriogenology 2002; 57:203-222.
17. Campbell KHS, McWhir J, Ritchie WA, Wilmut I. Sheep cloned by nuclear transfer from cultured cell line. Nature 1996; 380:64-66.
18. Zakhartchenko V, Durcova-Hills G, Stojkovic M, Schernthaner W, Prelle K, Steinborn R, Muller M, Brem G, Wolf E. Effects of serum starvation and re-cloning on the efficiency of nuclear transfer using bovine fetal fibroblasts. J Reprod Fertil 1999; 115:325-331.
19. Collas P, Pinto-Correia C, DeLeon FAP, Robl JM. Effect of donor cell cycle stage on chromatin and spindle morphology in nuclear transplant rabbit embryos. Biol Reprod 1992; 46:501-511.
20. Campbell KHS, Ritchie WA, Wilmut I. Nuclear-cytoplasmic interactions during the first cell cycle of nuclear transfer reconstructed bovine embryos: implications for deoxyribonucleic acid replication and development. Biol Reprod 1993; 49:933-942.
21. Campbell KH, Loi P, Otaegui PJ, Wilmut I. Cell cycle co-ordination in embryo cloning by nuclear transfer. Rev Reprod 1996; 1:40-46.
22. Stice SL, Keefer CL, Matthews L. Bovine nuclear transfer embryos: oocyte activation prior to blastomere fusion. Mol Reprod Dev 1994; 38:61-68.
23. Campbell KHS, Loi P, Cappai P, Wilmut I. Improved development to blastocyst of ovine nuclear transfer embryos reconstructed during the presumptive S-phase of enucleated activated oocytes. Biol Reprod 1994; 50:1385-1393.
24. Takada T, Iida K, Awaji T, Itoh K, Takahashi R, Shibui A, Yoshida K, Sugano S, Tsujimoto G. Selective production of transgenic mice using green fluorescent protein as a marker. Nat Biotechnol 1997; 15: 458-461.
25. Ono Y, Shimozawa N, Ito M, Kono T. Cloned mice from fetal fibroblast cells arrested at metaphase by a serial nuclear transfer. Biol Reprod 2001; 64:44-50.
26. Roh S, Shim H, Hwang WS, Yoon JT. In vitro development of green fluorescent protein (GFP) transgenic bovine embryos after nuclear transfer using different cell cycles and passages of fetal fibroblasts. Reprod Fertil Dev 2000; 12:1-6.
27. Arat S, Rzucidlo SJ, Gibbons J, Miyoshi K, Stice SL. Production of transgenic bovine embryos by transfer of transfected granulosa cells into enucleated oocytes. Mol Reprod Dev 2001; 60:20-26.
28. Cormack BP, Valdivia RH, Falkow S. FACS-optimized mutants of the green fluorescent protein (GFP). Gene 1996; 173:33-38.
29. Freshney RI. Culture of Animal Cells: A Manual of Basic Techniques. New York: Wiley-Liss; 1994:197-212.
30. Bordignon V, Smith LC. Telophase enucleation: an improved method to prepare recipient cytoplasts for use in bovine nuclear transfer. Mol Reprod Dev 1998; 49:29-36.
31. Viegas-Pequignot E, Dutrillaux B, Magdelenat H, Coppey-Moisan M. Mapping of single-copy DNA sequences on human chromosomes by in situ hybridization with biotinylated probes: enhancement of detection sensitivity by intensified-fluorescence digital-imaging microscopy. Proc Natl Acad Sci U S A 1989; 86:582-586.
32. Bilodeau AS, Lazaris A, Zhou JF, Duguay F, Keefer CL, Keyston R, Baldassarre H, Wang B, Karatzas CN. Localization of transgene integration in four dwarf BELE (breed early lactate early) founder goats by FISH analysis. Cytogenet Cell Genet 1999; 85:91.
33. Salisbury GW, Vandemark NL, Lodge JR. Physiology of Reproduction and Artificial Insemination of Cattle, 2 ed. San Francisco: W.H. Freeman & Company; 1978: 798.
34. Parrish JJ, Susko-Parrish JL, Leibfriedge-Ruthedge ML, Critser ES, Eyestone WH, First NL. Bovine in-vitro fertilization with frozen thawed semen. Theriogenology 1986; 25:591-600.
35. Park JH, Lee JH, Choi KM, Joung SY, Kim JY, Chung GM, Jin DI, Im KS. Rapid sexing of preimplantation bovine embryo using consecutive and multiplex polymerase chain reaction (PCR) with biopsied single blastomere. Theriogenology 2001; 55:1843-1853.
36. Telford NA, Watson AJ, Schultz GA. Transition from maternal to embryonic control in early mammalian development: a comparison of several species. Mol Reprod Dev 1990; 26:90-100.
37. Ikawa M, Yamada S, Nakanishi T, Okabe M. Green fluorescent protein (GFP) as a vital marker in mammals. Curr Top Dev Biol 1999; 44:1-20.
38. Park KW, Cheong HT, Lai L, Im GS, Kuhholzer B, Bonk A, Samuel M, Rieke A, Day BN, Murphy CN, Carter DB, Prather RS. Production of nuclear transfer-derived swine that express the enhanced green fluorescent protein. Anim Biotechnol 2001; 12:173-181.
39. Kato Y, Tani T, Sotomaru Y, Kurokawa K, Kato J, Doguchi H, Yasue H, Tsunoda Y. Eight calves cloned from somatic cells of a single adult. Science 1998; 282:2095-2098.
40. Campbell KH. Nuclear transfer in farm animal species. Semin Cell Dev Biol 1999; 10:245-252.
41. Bordignon V, Clarke HJ, Smith LC. Developmentally regulated loss and reappearance of immunoreactive somatic histone H1 on chromatin of bovine morula-stage nuclei following transplantation into oocytes. Biol Reprod 1999; 61:22-30.
42. Bordignon V, Clarke HJ, Smith LC. Factors controlling the loss of immunoreactive somatic histone H1 from blastomere nuclei in oocyte cytoplasm: a potential marker of nuclear reprogramming. Dev Biol 2001; 233:192-203.
43. Park KW, Lai L, Cheong HT, Im GS, Sun QY, Wu G, Day BN, Prather RS. Developmental potential of porcine nuclear transfer embryos derived from transgenic fetal fibroblasts infected with the gene for the green fluorescent protein: comparison of different fusion/activation conditions. Biol Reprod 2001; 65:1681-1685.
44. Uhm SJ, Kim NH, Kim T, Chung HM, Chung KH, Lee HT, Chung KS. Expression of enhanced green fluorescent protein (EGFP) and neomycin resistant (Neo(R)) genes in porcine embryos following nuclear transfer with porcine fetal fibroblasts transfected by retrovirus vector. Mol Reprod Dev 2000; 57:331-337.
45. Heyman Y, Chavatte-Palmer P, Lebourhis D, Camous S, Vignon X, Renard JP. Frequency and occurrence of late-gestation losses from cattle cloned embryos. Biol Reprod 2002; 66:6-13.
46. Hill JR, Roussel AJ, Cibelli JB, Edwards JF, Hooper NL, Miller MW, Thompson JA, Looney CR, Westhusin ME, Robl JM, Stice SL. Clinical and pathologic features of cloned transgenic calves and fetuses (13 case studies). Theriogenology 1999; 51:1451-1465.
47. Chavatte-Palmer P, Heyman Y, Richard C, Monget P, Lebourhis D, Kann G, Chilliard Y, Vignon X, Renard JP. Clinical, hormonal, and hematologic characteristics of bovine calves derived from nuclei from somatic cells. Biol Reprod 2002; 66:1596-1603.
48. Arat S, Gibbons J, Rzucidlo SJ, Respess DS, Tumlin M, Stice SL. In vitro development of bovine nuclear transfer embryos from transgenic clonal lines of adult and fetal fibroblast cells of the same genotype. Biol Reprod 2002; 66:1768-1774.
49. Huang W-Y, Aranburu J, Douglas PS, Izumo S. Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy. Nat Med 2000; 6:482-483.
50. Allen ND, Norris ML, Surani MA. Epigenetic control of transgene expression and imprinting by genotype-specific modifiers. Cell 1990; 61:853-861.
51. Sapienza C, Paquette J, Tran TH, Peterson A. Epigenetic and genetic factors affect transgene methylation imprinting. Development 1989; 107:165-168.