메뉴 건너뛰기




Volumn 26, Issue 4, 2003, Pages 313-319

Heterogeneity in the human response to immunostimulatory CpG oligodeoxynucleotides

Author keywords

CpG oligonucleotides; Cytokines; Heterogeneity; Human PBMC; Immune response; Immunoglobulin

Indexed keywords

IMMUNOGLOBULIN M; INTERLEUKIN 6; OLIGODEOXYNUCLEOTIDE;

EID: 0037829434     PISSN: 10538550     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002371-200307000-00003     Document Type: Article
Times cited : (34)

References (25)
  • 1
    • 0026464967 scopus 로고
    • DNA from bacteria, but not vertebrates, induces interferons, activate NK cells and inhibits tumor growth
    • Yamamoto S, Yamamoto T, Shimada S, et al. DNA from bacteria, but not vertebrates, induces interferons, activate NK cells and inhibits tumor growth. Microbiol Immunol. 1992;36:983-997.
    • (1992) Microbiol Immunol , vol.36 , pp. 983-997
    • Yamamoto, S.1    Yamamoto, T.2    Shimada, S.3
  • 2
    • 0026006734 scopus 로고
    • Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA
    • Messina JP, Gilkeson GS, Pisetsky DS. Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. J Immunol. 1991;147:1759-1764.
    • (1991) J Immunol , vol.147 , pp. 1759-1764
    • Messina, J.P.1    Gilkeson, G.S.2    Pisetsky, D.S.3
  • 3
    • 0028931102 scopus 로고
    • CpG motifs in bacterial DNA trigger direct B-cell activation
    • Krieg AM, Yi A, Matson S, et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature. 1995;374:546-548.
    • (1995) Nature , vol.374 , pp. 546-548
    • Krieg, A.M.1    Yi, A.2    Matson, S.3
  • 4
    • 0031867535 scopus 로고    scopus 로고
    • Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
    • Sparwasser T, Koch E, Vabulas RM, et al. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur J Immunol. 1998;28:2045-2054.
    • (1998) Eur J Immunol , vol.28 , pp. 2045-2054
    • Sparwasser, T.1    Koch, E.2    Vabulas, R.M.3
  • 5
    • 0029984358 scopus 로고    scopus 로고
    • CpG motifs expressed by bacterial DNA rapidly induce lymphocytes to secrete IL-6, IL-12 and IFNγ
    • Klinman DM, Yi A, Beaucage SL, et al. CpG motifs expressed by bacterial DNA rapidly induce lymphocytes to secrete IL-6, IL-12 and IFNγ. Proc Natl Acad Sci USA. 1996;93:2879-2883.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2879-2883
    • Klinman, D.M.1    Yi, A.2    Beaucage, S.L.3
  • 6
    • 0026625208 scopus 로고
    • Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN and augment IFN-mediated natural killer activity
    • Yamamoto S, Yamamoto T, Katoaka T, et al. Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN and augment IFN-mediated natural killer activity. J Immunol. 1992;148:4072-4076.
    • (1992) J Immunol , vol.148 , pp. 4072-4076
    • Yamamoto, S.1    Yamamoto, T.2    Katoaka, T.3
  • 8
    • 0033563211 scopus 로고    scopus 로고
    • Long-term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides
    • Sur S, Wild JS, Choudhury BK, et al. Long-term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides. J Immunol. 1999;162:6284-6291.
    • (1999) J Immunol , vol.162 , pp. 6284-6291
    • Sur, S.1    Wild, J.S.2    Choudhury, B.K.3
  • 9
    • 0033558121 scopus 로고    scopus 로고
    • Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria
    • Elkins KL, Rhinehart-Jones TR, Stibitz S, et al. Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria. J Immunol. 1999;162:2291-2298.
    • (1999) J Immunol , vol.162 , pp. 2291-2298
    • Elkins, K.L.1    Rhinehart-Jones, T.R.2    Stibitz, S.3
  • 10
    • 0030955249 scopus 로고    scopus 로고
    • Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization
    • Weiner GJ, Liu HM, Wooldridge JE, et al. Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization. Proc Nat Acad Sci USA. 1997;94:10833-10837.
    • (1997) Proc Nat Acad Sci USA , vol.94 , pp. 10833-10837
    • Weiner, G.J.1    Liu, H.M.2    Wooldridge, J.E.3
  • 11
    • 0032810718 scopus 로고    scopus 로고
    • DNA activates human immune cells through a CpG sequence-dependent manner
    • Bauer M, Heeg K, Wagner H, et al. DNA activates human immune cells through a CpG sequence-dependent manner. Immunology. 1999;97:699-705.
    • (1999) Immunology , vol.97 , pp. 699-705
    • Bauer, M.1    Heeg, K.2    Wagner, H.3
  • 12
    • 0034650517 scopus 로고    scopus 로고
    • Mechanism and function of a newly identified CpG DNA motif in human primary B cells
    • Hartmann G, Krieg AM. Mechanism and function of a newly identified CpG DNA motif in human primary B cells. J Immunol. 2000;164:944-952.
    • (2000) J Immunol , vol.164 , pp. 944-952
    • Hartmann, G.1    Krieg, A.M.2
  • 13
    • 0035865054 scopus 로고    scopus 로고
    • Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs
    • Verthelyi D, Ishii KJ, Gursel M, et al. Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs. J Immunol. 2001;166:2372-2377.
    • (2001) J Immunol , vol.166 , pp. 2372-2377
    • Verthelyi, D.1    Ishii, K.J.2    Gursel, M.3
  • 14
    • 0030764558 scopus 로고    scopus 로고
    • Immunostimulatory DNA sequences function as T helper-1 promoting adjuvants
    • Roman M, Martin-Orozco E, Goodman JS, et al. Immunostimulatory DNA sequences function as T helper-1 promoting adjuvants. Nat Medicine. 1997;3:849-854.
    • (1997) Nat Medicine , vol.3 , pp. 849-854
    • Roman, M.1    Martin-Orozco, E.2    Goodman, J.S.3
  • 15
    • 0029738445 scopus 로고    scopus 로고
    • Activation of human B cells by phosphorothioate oligodeoxynucleotides
    • Liang H, Nishioka Y, Reich CF, et al. Activation of human B cells by phosphorothioate oligodeoxynucleotides. J Clin Invest. 1996;98:1119-1129.
    • (1996) J Clin Invest , vol.98 , pp. 1119-1129
    • Liang, H.1    Nishioka, Y.2    Reich, C.F.3
  • 16
    • 0034667770 scopus 로고    scopus 로고
    • Phosphorothioate backbone modification modulates macrophage activation by CpG DNA
    • Sester DP, Naik S, Beasley J, et al. Phosphorothioate backbone modification modulates macrophage activation by CpG DNA. J Immunol. 2000;165:4165-4173.
    • (2000) J Immunol , vol.165 , pp. 4165-4173
    • Sester, D.P.1    Naik, S.2    Beasley, J.3
  • 17
    • 0034668209 scopus 로고    scopus 로고
    • Oral, intrarectal and intranasal immunizations using CpG and non-CpG oligodeoxynucleotides as adjuvants
    • McCluskie MJ, Davis HL. Oral, intrarectal and intranasal immunizations using CpG and non-CpG oligodeoxynucleotides as adjuvants. Vaccine. 2000;19:413-422.
    • (2000) Vaccine , vol.19 , pp. 413-422
    • McCluskie, M.J.1    Davis, H.L.2
  • 18
    • 0030850462 scopus 로고    scopus 로고
    • CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: A new class of vaccine adjuvants
    • Lipford GB, Bauer M, Blank C, et al. CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants. Eur J Immunol. 1997;27:2340-2344.
    • (1997) Eur J Immunol , vol.27 , pp. 2340-2344
    • Lipford, G.B.1    Bauer, M.2    Blank, C.3
  • 19
    • 0032521274 scopus 로고    scopus 로고
    • Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma
    • Kline JN, Waldschmidt TJ, Businga TR, et al. Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma. J Immunol. 1998;160:2555-2559.
    • (1998) J Immunol , vol.160 , pp. 2555-2559
    • Kline, J.N.1    Waldschmidt, T.J.2    Businga, T.R.3
  • 20
    • 0031964257 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen
    • Davis HL, Weeranta R, Waldschmidt TJ, et al. CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J Immunol. 1998;160:870-876.
    • (1998) J Immunol , vol.160 , pp. 870-876
    • Davis, H.L.1    Weeranta, R.2    Waldschmidt, T.J.3
  • 21
    • 0035869506 scopus 로고    scopus 로고
    • Oligodeoxynucleotides containing CpG motifs induce low levels of TNF-alpha in human B lymphocytes: Possible adjuvants for Th1 responses
    • Bohle B, Orel L, Kraft D, et al. Oligodeoxynucleotides containing CpG motifs induce low levels of TNF-alpha in human B lymphocytes: possible adjuvants for Th1 responses. J Immunol. 2001;166:3743-3748.
    • (2001) J Immunol , vol.166 , pp. 3743-3748
    • Bohle, B.1    Orel, L.2    Kraft, D.3
  • 22
    • 0034142182 scopus 로고    scopus 로고
    • Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo
    • Hartmann G, Weeratna RD, Ballas ZK, et al. Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. J Immunol. 2000;164:1617-1624.
    • (2000) J Immunol , vol.164 , pp. 1617-1624
    • Hartmann, G.1    Weeratna, R.D.2    Ballas, Z.K.3
  • 23
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi H, Takeuchi O, Kawai T, et al. A Toll-like receptor recognizes bacterial DNA. Nature. 2000;408:740-745.
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1    Takeuchi, O.2    Kawai, T.3
  • 24
    • 0035477969 scopus 로고    scopus 로고
    • Cutting edge: Role of toll-like receptor 9 in CpG DNA-induced activation of human cells
    • Takeshita F, Leifer CA, Gursel I, et al. Cutting edge: role of toll-like receptor 9 in CpG DNA-induced activation of human cells. J Immunol. 2001;167:3555-3558.
    • (2001) J Immunol , vol.167 , pp. 3555-3558
    • Takeshita, F.1    Leifer, C.A.2    Gursel, I.3
  • 25
    • 0035979192 scopus 로고    scopus 로고
    • Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
    • Bauer S, Kirschning CJ, Hacker H, et al. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc Nat Acad Sci USA. 2001;98:9237-9242.
    • (2001) Proc Nat Acad Sci USA , vol.98 , pp. 9237-9242
    • Bauer, S.1    Kirschning, C.J.2    Hacker, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.