Streptococcus pneumoniae hyaluronate lyase contains two non-cooperative independent folding/unfolding structural domains: Characterization of functional domain and inhibitors of enzyme

Journal of Biological Chemistry

Volumn 278, Issue 28, 2003, Pages 25509-25516

  Akhtar, Sohail ^a   Bhakuni, Vinod ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOLOGY; ESTERS; THERMODYNAMIC STABILITY; TISSUE;

PROTEOLYSIS;

ENZYMES;

ARGININE; ARGININE METHYL ESTER; ENZYME INHIBITOR; GUANIDINE; GUANIDINE DERIVATIVE; GUANIDINE ISOTHIOCYANATE; HYALURONATE LYASE; LYASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME DENATURATION; ENZYME ISOLATION; ENZYME MECHANISM; ENZYME STRUCTURE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STABILITY; STREPTOCOCCUS PNEUMONIAE; THERMOSTABILITY;

ARGININE; CALCIUM CHLORIDE; CIRCULAR DICHROISM; CLONING, MOLECULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GUANIDINE; GUANIDINES; INHIBITORY CONCENTRATION 50; ISOTHIOCYANATES; MAGNESIUM CHLORIDE; NG-NITROARGININE METHYL ESTER; POLYSACCHARIDE-LYASES; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, FLUORESCENCE; STREPTOCOCCUS PNEUMONIAE; TEMPERATURE;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

EID: 0037815288     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M301894200     Document Type: Article

References (29)

1. Mufson, M. A. (1990) Principles and Practice of Infectious Diseases (Mandell, G. L., Douglas, R. G., Jr., and Bennett, J. E., eds) pp. 1539-1550, Publisher, Location of Publisher
2. Jonston, R. B., Jr. (1991) Rev. Infect. Dis. 13, S509-S517
3. Musher, D. M. (1991) Clin. Infect. Dis. 14, 801-807
4. Gray, B. M., Converse, G. M., III, and Dillion, H. C., Jr. (1980) J. Infect. Dis. 142, 923-933
5. Menzel, E. J., and Farr, C. (1998) Cancer Lett. 131, 3-11
6. Park, Y., Cho, S., and Linhardt, R. J. (1997) Biochim. Biophys. Acta 1337, 217-226
7. Boulnois, G. J. (1992) J. Gen. Microbiol. 138, 249-259
8. Jedrzejas, M. K. (2000) Microbiol. Mol. Biol. Rev. 65, 187-207
9. Feldman, C., Munro, N. C., Jeffery, P. K., Mitchell, T. J., Andrew, P. W., Boulnois, G. J., Guerreiro, D., Rhode, J. A., Todd, H. C., and Cole, P. J. (1992) Am. J. Respir. Cell Mol. Biol. 5, 416-423
10. Berry, A. M., Lock, R. A., Thomas, S. M., Rajan, D. P., Hansman, D., and Paton, J. C. (1994) Infect. Immun. 62, 1101-1108
11. Lin, B., Hollingshead, S. K., Coligan, J. E., Egan, M. L., Baker, J. R., and Pritchard, D. (1994) J. Biol. Chem. 269, 30113-30116
12. Farrell, A. M., Taylor, D., and Holland, K. J. (1995) FEMS Microbiol. Lett. 130, 81-85
13. Steiner, B. M., Romero-Steiner, S., Cruce, D., and George, R. (1997) Can. J. Microbiol. 43, 315-321
14. Li, S., Kelly, S. J., Lamani, E., Ferraroni, M., and Jedrzejas, M. K. (2000) EMBO J. 19, 1228-1240
15. Li, S., and Jedrzejas, M. J. (2001) J. Biol. Chem. 276, 41407-41416
16. Ponnuraj, K., and Jedrzejas, M. J. (2000) J. Mol. Biol. 299, 885-895
17. Li, S., Taylor, K. B., Kelly, S. J., and Jedrzejas, M. J. (2001) J. Biol. Chem. 276, 15125-15130
18. Paton, J. C., Berry, A. M., Lock, R., Hansman, D., and Manning, P. A. (1986) Infect. Immun. 54, 50-55
19. Jedrzejas, M. J., Mewbourne, R. B., Chantalat, L., and McPherson, D. T. (1998) Protein Expr. Purif. 13, 83-89
20. Pritchard, D. J., Lin, B., Willingham, T. R., and Baker, J. R. (1994) Arch. Biochem. Biophys. 315, 431-437
21. Praksh, K., Prajapati, S., Ahmad, A., Jain, S. K., and Bhakuni, V. (2002) Prot. Sci. 11, 46-57
22. Akhtar, M. S., Ahmad, A., and Bhakuni, V. (2002) Biochemistry, 41, 7142-7149
23. Pritchard, D. J., Trent, J. O., Zhang, P., Egan, M. L., and Baker, J. R. (2000) Proteins Struct. Funct. Genet. 40, 126-134
24. Fethiere, J., Eggimann, B., and Cygler, M. (1999) J. Mol. Biol. 288, 635-641
25. Hubbard, S. J. (1998) Biochim. Biophys. Acta 1382, 191-206
26. Sevcik, J., Hostinova, E., Gasperik, J., Solovicova, A., Wilson, K. S., and Dauter, Z. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 854-866
27. Yoon, H. J., Mikami, B., Hashimoto, W., and Murata, K. (1999) J. Mol. Biol. 290, 505-514
28. Rollend, K., Marois, C., Siqyier, V., Cattier, B., and Quentin, R. (1999) J. Clin. Microbiol. 37, 1892-1898
29. Berry, A. M., and Paton, J. C. (2000) Infect. Immun. 68, 133-140