Different roles for the stress-activated protein kinase pathway in the regulation of trehalose metabolism in Schizosaccharomyces pombe

Microbiology

Volumn 149, Issue 7, 2003, Pages 1745-1752

  Paredes, V ^a   Franco, A ^a   Soto, T ^a   Vicente Soler, J ^a   Gacto, M ^a   Cansado, J ^a  

^a UNIVERSITY OF MURCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL ENZYME; MITOGEN ACTIVATED PROTEIN KINASE; NEUTRAL TREHALASE; SODIUM CHLORIDE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TREHALASE; TREHALOSE; TREHALOSE 6 PHOSPHATE SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; ENZYME ACTIVATION; ENZYME ACTIVITY; EXPOSURE; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; METABOLITE; NONHUMAN; OSMOTIC STRESS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTECTION; REGULATORY MECHANISM; SCHIZOSACCHAROMYCES POMBE; SIGNAL TRANSDUCTION; STRESS; YEAST;

SCHIZOSACCHAROMYCES POMBE;

EID: 0037810921     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.26279-0     Document Type: Article

References (33)

1. Blázquez, M. A., Stucka, R., Feldmann, H. & Gancedo, C. (1994). Trehalose-6-P synthase is dispensable for growth on glucose but not for spore germination in Schizosaccharomyces pombe. J Bacteriol 176, 3895-3902.
2. Boeke, J. D., La Croute, F. & Fink, G. R. (1984). A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol Gen Genet 197, 345-346.
3. Cansado, J., Soto, T., Fernández, J., Vicente-Soler, J. & Gacto, M. (1998). Characterization of mutants devoid of neutral trehalase activity in the fission yeast Schizosaccharomyces pombe: partial protection from heat shock and high-salt stress. J Bacteriol 180, 1342-1345.
4. Carrillo, D., Vicente-Soler, J. & Gacto, M. (1994). Cyclic AMP signaling pathway and trehalase activation in the fission yeast Schizosaccharomyces pombe. Microbiology 140, 1467-1472.
5. + gene product. J Cell Sci 110, 2599-2608.
6. Chen, D., Toone, W. M., Mata, J., Lyne, R., Burns, G., Kirinen, K., Brazma, A., Jones, N. & Bähler, J. (2003). Global transcriptional responses of fission yeast to environmental stress. Mol Biol Cell 14, 214-219.
7. Crowe, J. H., Crowe, L. M. & Chapman, D. (1984). Preservation of membranes in anhydrobiotic organisms: the role of trehalose. Science 223, 701-703.
8. Degols, G., Shiozaki, K. & Russell, P. (1996). Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe. Mol Cell Biol 16, 2870-2877.
9. Fernández, J., Soto, T., Vicente-Soler, J., Cansado, J. & Gacto, M. (1997a). Heat-shock response in Schizosaccharomyces pombe cells lacking cyclic AMP-dependent phosphorylation. Curr Genet 31, 112-118.
10. Fernández, J., Soto, T., Vicente-Soler, J., Cansado, J. & Gacto, M. (1997b). Osmo-stress-induced changes in neutral trehalase activity of the fission yeast Schizosaccharomyces pombe. Biochim Biophys Acta 1357, 41-48.
11. Fernández, J., Soto, T., Franco, A., Vicente-Soler, J., Cansado, J. & Gacto, M. (1998). Enhancement of neutral trehalase activity by oxidative stress in the fission yeast Schizosaccharomyces pombe. Fungal Genet Biol 25, 79-86.
12. + as encoding a main trehalose-6P phosphatase in the fission yeast Schizosaccharomyces pombe. J Bacteriol 182, 5880-5884.
13. Higuchi, R., Krummel, B. & Saiki, R. K. (1988). A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res 16, 7351-7367.
14. Hottiger, T., De Virgilio, C., Hall, M. N., Boller, T. & Wiemken, A. (1994). The role of trehalose synthesis for the acquisition of thermotolerance in yeast. I. Genetic evidence that trehalose is a thermoprotectant. II. Physiological concentrations of trehalose increase the thermal stability of proteins in vitro. Eur J Biochem 219, 187-193.
15. Kato, T., Okazaki, K., Murakami, H., Stettler, S., Fantes, P. & Okayama, H. (1996). Stress signal, mediated by a Hog1-like MAP kinase, controls sexual development in fission yeast. FEBS Lett 378, 207-212.
16. Maeda, T., Watanabe, Y., Kunimoto, H. & Yamamoto, M. (1994). Cloning of the pka1 gene encoding the catalytic Subunit of the cAMP dependent protein kinase in Schizosaccharomyces pombe. J Biol Chem 269, 9632-9637.
17. Millar, J. B. A., Buck, V. & Wilkinson, M. G. (1995). Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast. Genes Dev 9, 2117-2130.
18. Moreno, S., Klar, A. & Nurse, P. (1991). Molecular genetic analysis of the fission yeast Schizosaccharomyces pombe. Methods Enzymol 194, 795-823.
19. Neely, L. A. & Hoffman, C. S. (2000). Protein kinase A and mitogen-activated protein kinase pathways antagonistically regulate fission yeast fbp1 transcription by employing different modes of action at two upstream activation sites. Mol Cell Biol 20, 6426-6434.
20. 2 levels in fission yeast Schizosaccharomyces pombe. Mol Biol Cell 13, 805-816.
21. Shiozaki, K. & Russell, P. (1995). Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast. Nature 378, 739-743.
22. Shiozaki, K. & Russell, P. (1996). Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast. Genes Dev 10, 2276-2288.
23. Singer, M. A. & Lindquist, S. (1998). Multiple effects of trehalose on protein folding in vitro and in vivo. Mol Cell 1, 639-648.
24. Soto, T., Fernández, J., Domínguez, A., Vicente-Soler, J., Cansado, J. & Gacto, M. (1998). Analysis of the ntp1? gene, encoding neutral trehalase in the fission yeast Schizosaccharomyces pombe. Biochim Biophys Acta 1443, 225-229.
25. Soto, T., Fernández, J., Vicente-Soler, J., Cansado, J. & Gacto, M. (1999). Accumulation of trehalose by overexpression of tps1, coding for trehalose-6-phosphate synthase, causes increased resistance to multiple stresses in the fission yeast Schizosaccharomyces pombe. Appl Environ Microbiol 65, 2020-2024.
26. + encodes a transcription factor required for sexual development and entry into stationary phase. EMBO J 14, 6193-6208.
27. Toone, W. M. & Jones, N. (1999). AP-1 transcription factors in yeast. Curr Opin Genet Dev 9, 55-61.
28. Toone, W. M., Kuge, S., Samuels, S., Morgan, B. A., Toda, T. & Jones, N. (1998). Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev 12, 1453-1463.
29. Wahls, W. P. & Smith, G. R. (1994). A heteromeric protein that binds to a meiotic homologous recombination hot spot: correlation of binding and hot spot activity. Genes Dev 8, 1693-1702.
30. Warbrick, E. & Fantes, P. (1991). The wis1 protein kinase is a dosage-dependent regulator of mitosis in Schizosaccharomyces pombe. EMBO J 10, 4291-4299.
31. + encodes a CREB/ATF protein involved in regulation of gene expression for sexual development. Mol Cell Biol 16, 704-711.
32. Wilkinson, M. G. & Millar, J. B. A. (1998). SAPKs and transcription factors do the nucleocytoplasmic tango. Genes Dev 12, 1391-1397.
33. Wilkinson, M. G., Samuels, M., Takeda, T., Toone, M. W., Shieh, J., Toda, T., Millar, J. B. A. & Jones, N. (1996). The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast. Genes Dev 10, 2289-2301.