Relationship between the expression of E-cadherin-catenins and α-, β-, γ-catenin and the metastasis and prognosis of breast cancer

Bulletin of Hunan Medical University

Volumn 27, Issue 6, 2002, Pages 499-502

  Zou, Wen ^a   Hu, Chun Hong ^a   Zhou, Jian Ping ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Breast carcinoma; Catenins; E cadherin; Immunohistochemistry

Indexed keywords

ALPHA CATENIN; BETA CATENIN; PLAKOGLOBIN; UVOMORULIN; CADHERIN; CTNNA1 PROTEIN, HUMAN; CTNNB1 PROTEIN, HUMAN; CYTOSKELETON PROTEIN; TRANSACTIVATOR PROTEIN; TUMOR MARKER;

ARTICLE; BREAST CANCER; CANCER SURVIVAL; DIAGNOSTIC ACCURACY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; METASTASIS; PROGNOSIS; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY; ADULT; AGED; BREAST TUMOR; CHEMISTRY; FEMALE; FOLLOW UP; LYMPH NODE METASTASIS; MIDDLE AGED; PATHOLOGY; SURVIVAL RATE;

ADULT; AGED; ALPHA CATENIN; BETA CATENIN; BREAST NEOPLASMS; CADHERINS; CYTOSKELETAL PROTEINS; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; PROGNOSIS; SURVIVAL RATE; TRANS-ACTIVATORS; TUMOR MARKERS, BIOLOGICAL;

EID: 0037805198     PISSN: 10005625     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Gonzales MA, Pinder SE, Wencyk PM, et al. An immunohistochemical examination of the expression of E-cadherin, α- and β/γ -catenins, and α2- and β1-integrins in invasive breast cancer [J]. J Pathol, 1999, 187: 523-529.
2. Yoshida R, Kimura N, Harada Y, et al. The loss of E-cadherin, α- and β-catenin expression is associated with metastasis and poor prognosis in invasive breast cancer [J]. Int J Oncol, 2001, 18: 513-520.
3. Bohm J, Niskanen L, Kiraly K, et al. Expression and prognostic value of α-, β-, and γ-catenins indifferentiated thyroid carcinoma [J]. J Clin Endocrinol Metab, 2000, 85: 4806-4811.
4. Richmond PJM, Karayiannakis AJ, Nagafuchi A, et al. Aberrant E-cadherin and α-catenin expression in prostate: correlation with patient survival [J]. Cancer Res, 1997, 57: 3189-3193.
5. Dillon DA, D'Aquila T, Reynolds AB, et al. The expression of PI20 ctn protein in breast cancer is independent of α- and β-catenin and E-cadherin [J]. Am J Pathol, 1998, 152: 75-82.
6. Nagafuchi A, Takeichi M, Tsukita S. The 102kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expression [J]. Cell, 1991, 65: 849-857.
7. Rimm DL, Sinard JH, Morrow JS. Reduced α-catenin and E-cadherin expression in breast cancer [J]. Lab. Invest, 1995, 72: 506-512.
8. Bukholm IK, Nesland JM, Karesen R, et al. E-cadherin andα-, β- and γ-catenin protein expression in relation to metastasis in human breast carcinoma [J]. J Pathol, 1998, 185: 262-266.
9. Gillett CE, Miles DW, Ryder K, et al. Retention of the expression of E-cadherin and catenins is associated with shorter survival in grade III ductal carcinoma of the breast [J]. J Pathol, 2001, 193: 433-441.