HMG-CoA reductase, cholesterol 7α-hydroxylase, LCAT, ACAT, LDL receptor, and SRB-1 in hereditary analbuminemia

Kidney International

Volumn 64, Issue 1, 2003, Pages 192-198

  Liang, Kaihui ^a   Vaziri, Nosratola D ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ACAT; Bile acid; HDL; HMG CoA reductase; Hypercholesterolemia; Hyperlipidemia; Hypoalbuminemia; LCAT; LDL receptor; Nagase rats; Nephrotic syndrome

Indexed keywords

CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLESTEROL ACYLTRANSFERASE; HIGH DENSITY LIPOPROTEIN RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LOW DENSITY LIPOPROTEIN RECEPTOR; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE;

ANALBUMINEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HYPERCHOLESTEROLEMIA; HYPOALBUMINEMIA; MALE; NEPHROTIC SYNDROME; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; RAT; RAT STRAIN; TRANSLATION REGULATION;

EID: 0037792166     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2003.00041.x     Document Type: Article

References (33)

1. NAGASE S, SHIMAMUME K, SHUMIYA S: Albumin deficient rat mutant. Science Wash DC 205:590-591, 1979
2. KANEKO T, SHIMA H, ESUMI H, et al: Marked increases of two kinds of two-exon-skipped albumin mRNAs with aging and their further increase by treatment with 3′-methyl-4-dimethylaminoazobenzene in Nagase analbuminemic rats. Proc Natl Acad Sci USA 88:2707-2711, 1991
3. SHALABY F, SHAFRITZ DA: Exon skipping during splicing of albumin mRNA precursors in Nagase analbuminemic rats. Proc Natl Acad Sci USA 87:2652-2656, 1990
4. JOLES JA, WILLEKES-KOOLSCHIJN N, VAN TOL A, et al: Hyperlipoproteinemia in one-year-old analbuminemic rats. Atherosclerosis 88:35-47, 1991
5. VAN TOL A, JANSEN EH, KOOMANS HA, JOLES JA: Hyperlipoproteinemia in Nagase analbuminemic rats: Effects of pravastatin on plasma (apo)lipoproteins and lecithin:cholesterol acyltransferase activity. J Lipid Res 32:1719-1728, 1991
6. BALDO-ENZI G, BAIOCCHI MR, VIGNA G, et al: Analbuminaemia: A natural model of metabolic compensatory systems. J Inherit Metab Dis 10:317-329, 1987
7. SUN X, JONES H, JR, JOLES JA, et al: Apolipoprotein gene expression in analbuminemic rats and in rats with Heymann nephritis. Am J Physiol 262:F755-761, 1992
8. MARSH JB, DRABKIN DL: Experimental reconstruction of metabolic pattern of lipid nephrosis: Key role of hepatic protein synthesis in hyperlipidemia. Metab Clin 9:946-955, 1960
9. NESS GC, CHAMBERS CM, LOPEZ D: Atorvastatin action involves diminished recovery of hepatic HMG-CoA reductase activity. J Lipid Res 39:75-84, 1998
10. LIANG KH, OVEISI F, VAZIRI ND: Gene expression of hepatic cholesterol 7 alpha-hydroxylase in the course of puromycin-induced nephrosis. Kidney Int 49:855-860, 1996
11. VAZIRI ND, LIANG K: Downregulation of hepatic LDL receptor expression in experimental nephrosis. Kidney Int 50:887-893, 1996
12. VAZIRI ND, LIANG KH: Upregulation of acyl-coenzyme A: Cholesterol acyltransferase (ACAT) in nephrotic syndrome. Kidney Int 61:1769-1775, 2002
13. WANG J, GEBRE AK, ANDERSON RA, PARKS JS: Amino acid residue 149 of lecithin:cholesterol acyltransferase determines phospholipase A2 and transacylase fatty acyl specificity. J Biol Chem 272:280-286, 1997
14. LIANG K, VAZIRI ND: Downregulation of hepatic high-density lipoprotein receptor, SRB-1 in nephrotic syndrome. Kidney Int 56:621-626, 1999
15. VAZIRI ND, LIANG KH: Hepatic HMG-CoA reductase gene expression during the course of puromycin-induced nephrosis. Kidney Int 48:1979-1985, 1995
16. VAZIRI ND, LIANG K, PARK JS: Downregulation of hepatic lecithin:cholesterol acyltransferase (LCAT) gene expression in chronic renal failure. Kidney Int 59:2192-2196, 2001
17. DIETSCHY JM, TURLEY SD, SPADY DK: Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J Lipid Res 34:1637-1659, 1993
18. VAZIRI ND, SATO T, LIANG K: Molecular mechanisms of altered cholesterol metabolism in rats with spontaneous focal glomerulosclerosis. Kidney Int 63:1756-1763, 2003
19. JOLES JA, FEINGOLD KR, VAN TOL A, et al: Extrahepatic lipogenesis contributes to hyperlipidemia in the analbuminemic rat. Am J Physiol 265:F70-76, 1993
20. ZHANG X, JOLES JA, KOOMANS HA, et al: Excessive cholesterolemic response in analbuminemic rats fed a cholesterol-rich diet containing casein. J Nutr 122:520-527, 1992
21. RUSSELL DW, SETCHELL KD: Bile acid biosynthesis. Biochemistry 31:4737-4749, 1992
22. VLAHCEVIC ZR, HEUMAN DM, HYLEMON PB: Regulation of bile acid synthesis. Hepatology 13:590-600, 1991
23. BILLHEIMER JT, GILLIES PJ: Advances in Cholesterol Research, edited by ESFAHANI M, SWANEY JB, Caldwell (NJ), Telford Press, 1990, pp 7-45
24. CHANG CC, HUH HY, CADIGAN KM, CHANG TY: Molecular cloning and functional expression of human acyl-coenzyme A: Cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells. J Biol Chem 268:20747-20755, 1993
25. ANDERSON RA, JOYCE C, DAVIS M, et al: Identification of a form of acyl-CoA: Cholesterol acyltransferase specific to liver and intestine in nonhuman primates. J Biol Chem 273:26747-26754, 1998
26. OELKERS P, BEHARI A, CROMLEY D, et al: Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes. J Biol Chem 273:26765-26771, 1998
27. CASES S, NOVAK S, ZHENG YW, et al: ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization. J Biol Chem 273:26755-26764, 1998
28. CARR TP, HAMILTON RL, RUDEL LL: ACAT inhibitors decrease secretion of cholesteryl esters and apolipoprotein B by perfused livers of African green monkeys. J Lipid Res 36:25-36, 1995
29. CIANFLONE KM, YASRUEL Z, RODRIGUEZ MA, et al: Regulation of ApoB secretion from HepG2 cells: Evidence for a critical role for cholesteryl ester synthesis in the response to a fatty acid challenge. J Lipid Res 31:2045-2055, 1990
30. HUFF MW, TELFORD DE, BARRETT PH, et al: Inhibition of hepatic ACAT decreases ApoB secretion in miniature pigs fed a cholesterol-free diet. Arteriorscler Thromb 14:1498-1508, 1994
31. GLOMSET JA: The plasma lecithins:cholesterol acyltransferase reaction. J Lipid Res 9:155-167, 1968
32. KUIVENHOVEN JA, PRITCHARD H, HILL J, et al: The molecular pathology of lecithin:cholesterol acyltransferase (LCAT) deficiency syndromes. J Lipid Res 38:191-205, 1997
33. VAZIRI ND, LIANG K, PARK JS: Acquired lecithin: Cholesterol acyltransferase (LCAT) deficiency in nephrotic syndrome. Am J Physiol Renal Physiol 49:F823-F829, 2001