메뉴 건너뛰기




Volumn 39, Issue 1, 1998, Pages 75-84

Atorvastatin action involves diminished recovery of hepatic HBG-CoA reductase activity

Author keywords

Atorvastatin; HMG CoA reducrase inhibitors immunoblotting Northern blotting; Iovastatin; LDL receptor

Indexed keywords

ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE;

EID: 0031930805     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (59)

References (32)
  • 1
    • 0026448725 scopus 로고
    • The discovery and development of HMG-CoA reductase inhibitors
    • Endo, A. 1992. The discovery and development of HMG-CoA reductase inhibitors. J. Lipid Res. 33: 1569-1582.
    • (1992) J. Lipid Res. , vol.33 , pp. 1569-1582
    • Endo, A.1
  • 3
    • 0028267313 scopus 로고
    • Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed by serial quantitative arteriography: The Canadian Coronary Atherosclerosis Intervention Trial
    • Waters, D., L. Higginson, P. Gladstone, B. Kimball, M. L. May, S. J. Boccuzzi, J. Lesperance, and the CCAIT Study Group. 1994. Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed by serial quantitative arteriography: The Canadian Coronary Atherosclerosis Intervention Trial. Circulation. 89: 959-968.
    • (1994) Circulation , vol.89 , pp. 959-968
    • Waters, D.1    Higginson, L.2    Gladstone, P.3    Kimball, B.4    May, M.L.5    Boccuzzi, S.J.6    Lesperance, J.7    Group, T.C.S.8
  • 4
    • 0027987849 scopus 로고
    • Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group. 1994. Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet 344: 1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 5
    • 0028216618 scopus 로고
    • Regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase gene expression by sterols and non-sterols in rat liver
    • Ness, G. C., S. Eales, D. Lopez, and Z. Zhao. 1994. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression by sterols and non-sterols in rat liver. Arch. Biochem. Biophys. 308: 420-425.
    • (1994) Arch. Biochem. Biophys. , vol.308 , pp. 420-425
    • Ness, G.C.1    Eales, S.2    Lopez, D.3    Zhao, Z.4
  • 6
    • 0030027994 scopus 로고    scopus 로고
    • Inhibitors of cholesterol biosynthesis increase hepatic low density lipoprotein receptor protein degradation
    • Ness, G. C., Z. Zhao, and D. Lopez. 1996. Inhibitors of cholesterol biosynthesis increase hepatic low density lipoprotein receptor protein degradation. Arch. Biochem. Biophys. 325: 242-248.
    • (1996) Arch. Biochem. Biophys. , vol.325 , pp. 242-248
    • Ness, G.C.1    Zhao, Z.2    Lopez, D.3
  • 10
    • 0029019415 scopus 로고
    • Comparative effects of HMG-CoA reductase inhibitors on apoB production in the casein-fed rabbit: Atorvastatin versus lovastatin
    • Auerback, B. J., B. R. Krause, C. L. Bisgaier, and R. S. Newton. 1995. Comparative effects of HMG-CoA reductase inhibitors on apoB production in the casein-fed rabbit: atorvastatin versus lovastatin. Atherosclerosis. 115: 173-180.
    • (1995) Atherosclerosis , vol.115 , pp. 173-180
    • Auerback, B.J.1    Krause, B.R.2    Bisgaier, C.L.3    Newton, R.S.4
  • 11
    • 0030454106 scopus 로고    scopus 로고
    • Hypocholesterolemic actions of atorvastatin are associated with alterations on hepatic cholesterol metabolism and lipoprotein composition in the guinea pig
    • Conde, K., M. Vergara-Jimenez, B. R. Krause, R. S. Newton, and M. L. Fernandez. 1996. Hypocholesterolemic actions of atorvastatin are associated with alterations on hepatic cholesterol metabolism and lipoprotein composition in the guinea pig. J. Lipid Res. 37: 2372-2382.
    • (1996) J. Lipid Res. , vol.37 , pp. 2372-2382
    • Conde, K.1    Vergara-Jimenez, M.2    Krause, B.R.3    Newton, R.S.4    Fernandez, M.L.5
  • 12
    • 0027962698 scopus 로고
    • Thyroid hormone rapidly induces hepatic LDL receptor mRNA levels in hypophysectomized rats
    • Ness, G. C., and Z. Zhao. 1994. Thyroid hormone rapidly induces hepatic LDL receptor mRNA levels in hypophysectomized rats. Arch. Biochem. Biophys. 315: 199-202.
    • (1994) Arch. Biochem. Biophys. , vol.315 , pp. 199-202
    • Ness, G.C.1    Zhao, Z.2
  • 13
    • 0342912311 scopus 로고
    • Hydroxymethylglutaryl coenzyme a reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat liver
    • Singer, I. I., D. W. Kawka, D. M. Kazazes, A. W. Alberts, J. S. Chen, J. W. Huff, and G. C. Ness. 1984. Hydroxymethylglutaryl coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat liver. Proc. Natl. Acad. Sci. USA. 81: 5556-5560.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 5556-5560
    • Singer, I.I.1    Kawka, D.W.2    Kazazes, D.M.3    Alberts, A.W.4    Chen, J.S.5    Huff, J.W.6    Ness, G.C.7
  • 14
    • 0028245959 scopus 로고
    • Effects of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor and cholesterol 7α-hydroxylase
    • Ness, G. C., Z. Zhao, and R. K. Keller. 1994. Effects of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor and cholesterol 7α-hydroxylase. Arch. Biochem. Biophys. 311: 277-285.
    • (1994) Arch. Biochem. Biophys. , vol.311 , pp. 277-285
    • Ness, G.C.1    Zhao, Z.2    Keller, R.K.3
  • 15
    • 0028122029 scopus 로고
    • Effects of stimulated growth hormone secretion on age-related changes in plasma cholesterol and hepatic low density lipoprotein receptor mRNA concentrations. Mech
    • Walker, R. F., G. C. Ness, Z. Zhao, and B. B. Bercu. 1994. Effects of stimulated growth hormone secretion on age-related changes in plasma cholesterol and hepatic low density lipoprotein receptor mRNA concentrations. Mech. Ageing Dev. 75: 215-226.
    • (1994) Ageing Dev. , vol.75 , pp. 215-226
    • Walker, R.F.1    Ness, G.C.2    Zhao, Z.3    Bercu, B.B.4
  • 16
    • 0027489201 scopus 로고
    • Loss of resistance to dietary cholesterol in the rat after hypophysectomy: Importance of the presence of growth hormone for hepatic LDL receptor expression
    • Rudling, M., and G. Angelin. 1993. Loss of resistance to dietary cholesterol in the rat after hypophysectomy: importance of the presence of growth hormone for hepatic LDL receptor expression. Proc. Natl. Acad. Sci. USA. 90: 8851-8855.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8851-8855
    • Rudling, M.1    Angelin, G.2
  • 17
    • 0028865447 scopus 로고
    • Transcriptional regulation of rat hepatic low density lipoprotein receptor and cholesterol 7α-hydroxylase by thyroid hormone
    • Ness, G. C., and D. Lopez. 1995. Transcriptional regulation of rat hepatic low density lipoprotein receptor and cholesterol 7α-hydroxylase by thyroid hormone. Arch. Biochem. Biophys. 323: 404-408.
    • (1995) Arch. Biochem. Biophys. , vol.323 , pp. 404-408
    • Ness, G.C.1    Lopez, D.2
  • 18
    • 0029113047 scopus 로고
    • Lipid-lowering activity of atorvastatin and lovastatin in rodent species: Triglyceride-lowering in rats correlates with efficacy in LDL animal models
    • Krause, B. R., and R. S. Newton. 1995. Lipid-lowering activity of atorvastatin and lovastatin in rodent species: triglyceride-lowering in rats correlates with efficacy in LDL animal models. Atherosclerosis. 117: 237-244.
    • (1995) Atherosclerosis , vol.117 , pp. 237-244
    • Krause, B.R.1    Newton, R.S.2
  • 19
    • 0000812012 scopus 로고    scopus 로고
    • Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver
    • Keller, R. K., Z. Zhao, C. Chambers and G. C. Ness. 1996. Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver. Arch. Biochem. Biophys. 328: 324-330.
    • (1996) Arch. Biochem. Biophys. , vol.328 , pp. 324-330
    • Keller, R.K.1    Zhao, Z.2    Chambers, C.3    Ness, G.C.4
  • 20
    • 0024238625 scopus 로고
    • Transcriptional and postranscriptional regulation of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme a reductase by thyroid hormone
    • Simonet, W. S., and G. C. Ness. 1988. Transcriptional and postranscriptional regulation of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase by thyroid hormone. J. Biol. Chem. 263: 12448-12453.
    • (1988) J. Biol. Chem. , vol.263 , pp. 12448-12453
    • Simonet, W.S.1    Ness, G.C.2
  • 21
    • 0031044655 scopus 로고    scopus 로고
    • Increased expression of low-density lipoprotein receptors in a Smith-Lemli-Opitz infant with elevated bilirubin levels
    • Ness, G. C., D. Lopez, O. Borrego, and E. Gilbert-Barness. 1997. Increased expression of low-density lipoprotein receptors in a Smith-Lemli-Opitz infant with elevated bilirubin levels. Am. J. Med. Genet. 68: 294-299.
    • (1997) Am. J. Med. Genet. , vol.68 , pp. 294-299
    • Ness, G.C.1    Lopez, D.2    Borrego, O.3    Gilbert-Barness, E.4
  • 22
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal. Biochem. 162: 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 23
    • 0022516611 scopus 로고
    • Characteristics of rat liver microsomal 3-hydroxy-3-methylglutaryl coenzyme a reductase
    • Ness, G. C., C. E. Sample, M. Smith, L. C. Pendleton, and D. C. Eichler. 1986. Characteristics of rat liver microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase. Biochem. J. 233: 167-172.
    • (1986) Biochem. J. , vol.233 , pp. 167-172
    • Ness, G.C.1    Sample, C.E.2    Smith, M.3    Pendleton, L.C.4    Eichler, D.C.5
  • 24
    • 0030043251 scopus 로고    scopus 로고
    • The diurnal variation of hepatic HMG-CoA reductase activity is due to changes in the level of immunoreactive protein
    • Ness, G. C., and C. M. Chambers. 1996. The diurnal variation of hepatic HMG-CoA reductase activity is due to changes in the level of immunoreactive protein. Arch. Biochem. Biophys. 327: 41-44.
    • (1996) Arch. Biochem. Biophys. , vol.327 , pp. 41-44
    • Ness, G.C.1    Chambers, C.M.2
  • 25
    • 0023354328 scopus 로고
    • Loss of NADPH during assays of HMG-CoA reductase: Implications and approaches to minimize errors
    • Ness, G. C., L. C. Pendleton, and A. S. Pendleton. 1987. Loss of NADPH during assays of HMG-CoA reductase: implications and approaches to minimize errors. Lipids. 22: 409-412.
    • (1987) Lipids , vol.22 , pp. 409-412
    • Ness, G.C.1    Pendleton, L.C.2    Pendleton, A.S.3
  • 26
    • 0000883949 scopus 로고
    • Influence of thyroid hormones on L-α-glycerophosphate dehydrogenase and other dehydrogenases in various organs of the rat
    • Lee, Y. P., and H. A. Lardy. 1965. Influence of thyroid hormones on L-α-glycerophosphate dehydrogenase and other dehydrogenases in various organs of the rat. J. Biol. Chem. 240: 1427-1436.
    • (1965) J. Biol. Chem. , vol.240 , pp. 1427-1436
    • Lee, Y.P.1    Lardy, H.A.2
  • 29
    • 0024579340 scopus 로고
    • Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase mRNA in rat liver. Glucocorticoids block the stabilization caused by thyroid hormone
    • Simonet, W. S., and G. C. Ness. 1989. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA in rat liver. Glucocorticoids block the stabilization caused by thyroid hormone. J. Biol. Chem. 264: 569-573.
    • (1989) J. Biol. Chem. , vol.264 , pp. 569-573
    • Simonet, W.S.1    Ness, G.C.2
  • 30
    • 0030050055 scopus 로고    scopus 로고
    • Plasma mevalonic acid, an index of cholesterol synthesis in vivo, and responsiveness to HMG-CoA reductase inhibitors in familial hypercholesterolemia
    • Naoumova, R. P., A. D. Marais, J. Mountney, J. C. Firth, I N. B. Rendell, G. W. Taylor, and G. R. Thompson. 1996. Plasma mevalonic acid, an index of cholesterol synthesis in vivo, and responsiveness to HMG-CoA reductase inhibitors in familial hypercholesterolemia. Atherosclerosis. 119: 203-213.
    • (1996) Atherosclerosis , vol.119 , pp. 203-213
    • Naoumova, R.P.1    Marais, A.D.2    Mountney, J.3    Firth, J.C.4    Rendell, I.N.B.5    Taylor, G.W.6    Thompson, G.R.7
  • 31
    • 0031575766 scopus 로고    scopus 로고
    • Translational regulation of hepatic HMG-CoA reductase by dietary cholesterol
    • Chambers, C. M., and G. C. Ness. 1997. Translational regulation of hepatic HMG-CoA reductase by dietary cholesterol. Biochem. Biophys. Res. Commun. 232: 278-281.
    • (1997) Biochem. Biophys. Res. Commun. , vol.232 , pp. 278-281
    • Chambers, C.M.1    Ness, G.C.2
  • 32
    • 0004852203 scopus 로고
    • Bile acids regulate hepatic low density lipoprotein receptor activity in the hamster by altering cholesterol flux across the liver
    • Spady, D. K., E. F. Stange, L. E. Bilhartz, and J. M. Dietschy. 1986. Bile acids regulate hepatic low density lipoprotein receptor activity in the hamster by altering cholesterol flux across the liver. Prof. Natl. Acad. Sci. USA. 83: 1916-1920.
    • (1986) Prof. Natl. Acad. Sci. USA , vol.83 , pp. 1916-1920
    • Spady, D.K.1    Stange, E.F.2    Bilhartz, L.E.3    Dietschy, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.