Influence of gender, age and lifestyle factors on micronuclei frequency in healthy Japanese populations

Journal of Occupational Health

Volumn 45, Issue 3, 2003, Pages 179-181

  Ishikawa, Hitoshi ^a   Tian, Ying ^a   Yamauchi, Toru ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Age; Gender; Micronuclei; Smoking

Indexed keywords

CLASTOGEN;

ADULT; ARTICLE; ASSAY; CHROMOSOME ABERRATION; CONTROLLED STUDY; CYTOKINESIS; DIAGNOSTIC VALUE; DIET; DISEASE MARKER; DNA DAMAGE; DRINKING BEHAVIOR; ENVIRONMENTAL EXPOSURE; EXERCISE; FEMALE; GENE FREQUENCY; GENOTOXICITY; HUMAN; JAPAN; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL ANALYSIS; MICRONUCLEUS; OCCUPATIONAL EXPOSURE; SCORING SYSTEM; SISTER CHROMATID EXCHANGE; SMOKING; T LYMPHOCYTE; VITAMIN BLOOD LEVEL;

ADULT; AGE FACTORS; ANALYSIS OF VARIANCE; FEMALE; HUMANS; JAPAN; LIFE STYLE; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; SEX FACTORS; SMOKING;

EID: 0037787806     PISSN: 13419145     EISSN: None     Source Type: Journal    
DOI: 10.1539/joh.45.179     Document Type: Article

References (16)

1. H Norppa: Cytogenetic markers of susceptibility: influence of polymorphic carcinogen-metabolozing enzymes. Environ Health Perspect 105, 829-835 (1997)
2. K Trenz, A Rothfuss, P Schutz and G Speit: Mutagen sensitivity of peripheral blood from women carrying a BRCA1 or BRCA2 mutation. Mutat Res 500, 89-96 (2002)
3. D Scott, JB Barber, EL Levine, W Burrill and SA Roberts: Radiation-induced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases among breast cancer patients: a test for predisposition? Br J Cancer 77, 614-620 (1998)
4. M Fench, N Holland, W Chang, E Zeiger and S Bonassi: The Human MicroNucleus Project - An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans. Mutat Res 428, 271-283 (1999)
5. J Nagayama and M Nagayama: Influence of five methlsulphonyl PCB congeners on frequency of micronucleated cells in cultured human lymphocytes by cytokinesis block method. Fukuoka Acta Med 86, 190-196 (1995)
6. K Umegaki, M Higuchi, K Inoue and T Esashi: Influence of one bout of intensive running on lymphocyte micronucleus frequencies in endurance-trained and untrained men. Int J Sports Med 19, 581-585 (1998)
7. H Norppa, S Luomahaara, H Heikanen, S Roth, M Sorsa, L Renzi and C Lindholm: Micronucleus assay in lymphocytes as a tool to biomonitor human exposure to aneuploidogens and clastogens. Environ Mol Mutagen 101, 139-143 (1993)
8. N Tienko-Holland, T Ahlborn, X Loxe, N Shang, MT Smith and AJ Wyrobek: Micronuclei and developmental abnormalities in 4-day mouse embryos after paternal treatment with acrylamide. Environ Mol Mutagen 31, 206-217 (1998)
9. H Ishikawa, Y Tian and T Yamauchi: Induction of micronuclei formation in preimplantation mouse embryos after maternal treatment with 2-bromopropane. Reprod Toxicol 15, 81-85 (2001)
10. M Fenech: The cytokinesis-block micronucleus technique: A detailed description of the method and its application to genotoxicity studies in human populations. Mutat Res 285, 35-44 (1993)
11. C Bolognesi, A Abbondandolo, R Barale, R Casalone, L Dalpra, PM DeFerrari, F Degrassi, A Forni, L Lamberti, C Lando, L Migliore, P Padovani, R Puntoni, I Sbrana, M Stella and S Bonassi: Age-related increase of baseline frequencies of sister chromatid exchanges, chromosome aberrations, and micronuclei in human lymphocytes. Cancer Epidemiol Biomarkers Prev. 6, 249-256 (1997)
12. R Tomanin, C Ballarin, B Nardini, G Mastrangelo and F Sarto: Influence of smoking habit on the frequency of micronuclei in human lymphocytes by the cytokinesis block mehod. Mutagenesis 6, 123-126 (1991)
13. F Merlo, A Andreassen, A Weston, CF Pan, A Haugen, F Valerio, G Reggiardo, V Fontana, S Garte, R Puntoni and A Abbondandolo: Urinary excretion of 1-hydroxypyrene as a marker for exposure to urban air levels of polycyclic aromatic hydrocarbons. Cancer Epidemiol Biomarkers Prev 7, 147-155 (1998)
14. D Warshawsky, GK Livingston, M Fonouni-Fard and K LaDow: Induction of micronuclei and sister chromatid exchanges by polycyclic and N-heterocyclic aromatic hydrocarbons in cultured human lymphocytes. Environ Mol Mutagen 26, 109-118 (1995)
15. F Maffei, GC Forti, E Castelli, GF Stefanini, S Mattioli and P Hrelia: Biomarkers to assess the genetic damage induced by alcohol abuse in human lymphocytes. Mutat Res 514, 49-58 (2002)
16. S Pavanello and E Clonfero: Biological indicators of genotoxic risk and metabolic polymorphisms. Mutat Res 463, 285-308 (2000)