Morphologic characteristics of varicose veins: Possible role of metalloproteinases

Journal of Vascular Surgery

Volumn 38, Issue 1, 2003, Pages 162-169

  Woodside, Kenneth J ^a,b   Hu, Mingdao ^a,b   Burke, Ann ^a,b   Murakami, Maki ^a,b   Pounds, Lori L ^a,b   Killewich, Lois A ^a,b   Daller, John A ^a,b   Hunter, Glenn C ^a,b  

^a University of Texas Medical Branch ^*

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE;

ARTERY INTIMA PROLIFERATION; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MICROVASCULATURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SAPHENOUS VEIN; SMOOTH MUSCLE FIBER; VARICOSIS; WESTERN BLOTTING; ZYMOGRAPHY; AGED; BIOSYNTHESIS; FEMALE; IN VITRO STUDY; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY;

AGED; FEMALE; HUMANS; MALE; MATRIX METALLOPROTEINASES; MIDDLE AGED; SAPHENOUS VEIN; TISSUE INHIBITOR OF METALLOPROTEINASES; VARICOSE VEINS;

EID: 0037771303     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-5214(03)00134-4     Document Type: Article

References (18)

1. Evans CJ, Fowkes FG, Hajivassilion CA, Harper DR, Ruckley CV. Epidemiology of varicose veins: a review. Int Angiol 1994;13:263-70.
2. Adhikari A, Criqui MH, Wooll V, Denenberg JO, Fronek A, Langer RD, et al. The epidemiology of chronic venous disease. Phlebology 2000;15:2-18.
3. Badier-Commander C, Verbeuren T, Lebard C, Michel JB, Jacob MP. Increased TIMP/MMP ratio in varicose veins: A possible explanation for extracellular matric accumulation. J Pathol 2000;192:105-12.
4. Kockx MM, Knaapen MW, Bortier HE, Cromheeke KM, Boutherin-Falson O, Finet M. Vascular remodeling in varicose veins. Angiology 1998;49:871-7.
5. Sansilvestri-Morel ??, Nonotte I, Fournet-Bourguignon MP, Rupin A, Fabiani JN, Verbeuren TJ, et al. Abnormal deposition of extracellular matrix proteins by cultured smooth muscle cells from human varicose veins. J Vasc Res 1998;35:115-23.
6. Borden P, Heller RA. Transcriptional control of matrix metalloproteinases and the tissue inhibitors of matrix metalloproteinases. Crit Rev Eukaryot Gene Exp 1997;7:159-78.
7. Rose SS, Ahmed A. Some thoughts on the aetiology of varicose veins. J Cardiovasc Surg 1986;27:534-43.
8. Travers JP, Brookes CE, Evans J, Baker DM, Kent C, Makin GS, et al. Assessment of wall structure and composition of varicose veins with reference to collagen, elastin and smooth muscle content. Eur J Vasc Endovasc Surg 1996;11:230-7.
9. Gillespie DL, Patel A, Fileta B, Chang A, Barnes S, Flagg A, et al. Varicose veins possess greater quantities of MMP-1 than normal veins and demonstrate regional variation in MMP-1 and MMP-13. J Surg Res 2002;106:233-8.
10. Ventnri M, Bonavina L, Annoni F, Colombo L, Bntera C, Peracchia A, et al. Biochemical assay of collagen and elastin in the normal and varicose vein wall. J Surg Res 1996;60:245-8.
11. Michiels C, Arnould T, Thibaut-Vercruyssen R, Bouaziz N, Jassens D, Remacle J. Perfused human saphenous veins for the study of the origin of varicose veins: role of the endothelium and of hypoxia. Int Angiol 1997;16:134-41.
12. Parra JR, Cambria RA, Hower CD, Dassow MS, Freischlag JA, Seabrook GR, et al. Tissue inhibitor of metalloproteinase-1 is increased in the saphenofemoral junction of patients with varices in the leg. J Vasc Surg 1998;28:669-75.
13. George SJ, Zaltsman AB, Newby AC. Surgical preparative injury and neointima formation increase MMP-9 expression and MMP-2 activation in human saphenons vein. Cardiovasc Res 1997;33:447-59.
14. Li YY, McTiernan CF, Feldman AM. Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matric remodeling. Cardiovasc Res 2000;46:214-24.
15. Hanemaaijer R, Koolwijk P, le Clercq L, de Vree WJ, van Hinsbergh VW. Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells: effects of tumour necrosis factor alpha, interleukin 1 and phorbol ester. Biochem J 1993;296:803-9.
16. Chua CC, Hamdy RC, Chua BH. Angiotensin II induces TIMP-1 production in rat heart endothelial cells. Biochim Biophys Acta 1996; 1311:175-80.
17. Maier R, Ganu V, Lotz M. Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases. J Biol Chem 1993; 268:21527-32.
18. Richards CD, Agro A. Interaction between oncostatin M, interleukin 1 and prostaglandin E2 in induction of IL-6 expression in human fibroblasts. Cytokine 1994;6:40-7.