Atypical medullary breast carcinoma in a family carrying the 5382insC BRCA-1 mutation [3]

Breast Journal

Volumn 9, Issue 3, 2003, Pages 260-262

  Kroupis, Christos ^a   Lianidou, Evriklia ^a   Goutas, Nikos ^b   Ladopoulou, Angela ^c   Konstantopoulou, Irene ^c   Pantazidis, Alexandros ^c   Yannoukakos, Drakoulis ^c   Efstathiou, Eleni ^d   Vourlidis, Nikos ^e   Tsionou, Christina ^e  

^a UNIVERSITY OF ATHENS   (Greece)

^b Evgenidion Hospital   (Greece)

^c INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^d ALEXANDRA HOSPITAL   (Greece)

^e Gastroenterology Department   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRACEPTIVE AGENT; CYCLOPHOSPHAMIDE; DOXORUBICIN; ESTROGEN RECEPTOR; FLUOROURACIL; MONOCLONAL ANTIBODY KI 67; PROTEIN P53;

ADULT; ANEUPLOIDY; ASPIRATION BIOPSY; AXILLARY LYMPH NODE; BREAST CARCINOMA; CANCER GRADING; CANCER RISK; CANCER SCREENING; CASE REPORT; CLINICAL FEATURE; COLON CANCER; COST EFFECTIVENESS ANALYSIS; CYTOARCHITECTURE; DISEASE ASSOCIATION; DISEASE COURSE; DNA SEQUENCE; FAMILIAL CANCER; FAMILY; FAMILY HISTORY; FEMALE; GENE MUTATION; GENETIC ANALYSIS; GENETIC COUNSELING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LETTER; LYMPHOCYTIC INFILTRATION; MAMMOGRAPHY; MEDULLARY CARCINOMA; ONCOGENE; ONSET AGE; PEDIGREE; PENETRANCE; PHENOTYPE; PREMENOPAUSE; TREATMENT OUTCOME; TUMOR SUPPRESSOR GENE;

ADULT; BREAST NEOPLASMS; CARCINOMA, MEDULLARY; DIAGNOSIS, DIFFERENTIAL; FEMALE; GENES, BRCA1; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MUTATION; PEDIGREE;

EID: 0037764811     PISSN: 1075122X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1524-4741.2003.09326.x     Document Type: Letter

References (12)

1. Nathanson KN, Wooster R, Weber BL. Breast cancer genetics: what we know and what we need. Nat Med 2001;7:552-56.
2. Ponder BA. Cancer genetics. Nature 2001;411:336-41.
3. NYBCS Collaborative Group. Breast and ovarian cancer risks among women with BRCA1 and BRCA2 mutations in the New York breast cancer study. Am J Hum Genet 2001;68:292.
4. Lakhani SR, Jacquemier J, Sloane JP, et al. Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations. J Natl Cancer Inst 1998;90:1138-45.
5. Breast Cancer Linkage Consortium. Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases. Lancet 1997;349:1505-10.
6. Hedenfalk I, Duggan D, Chen Y, et al. Gene-expression profiles in hereditary breast cancer. N Engl J Med 2001;344:539-48.
7. Ansquer Y, Gautier C, Fourquet A, Asselain B, Stoppa-Lyonnet D. Survival in early-onset BRCA1 breast-cancer patients. Institut Curie Breast Cancer Group. Lancet 1998;352:541.
8. Ellis D, Greenman J, Hodgson S, et al. Low prevalence of germline BRCA1 mutations in early onset breast cancer without a family history. J Med Genet 2000;37:792-94.
9. Lidereau R, Eisinger F, Champeme MH, et al. Major improvement in the efficacy of BRCA1 mutation screening using morphoclinical features of breast cancer. Cancer Res 2000;60:1206-10.
10. Shousha S. Medullary carcinoma of the breast and BRCA1 mutation. Histopathology 2000;37:182-85.
11. Eisinger F, Jacquemier J, Charpin C, et al. Mutations at BRCA1: the medullary breast carcinoma revisited. Cancer Res 1998;58:1588-92.
12. Ladopoulou A, Kroupis C, Konstantopoulou I, et al. Germ line BRCA1 & BRCA2 mutations in Greek breast/ovarian cancer families: 5382insC is the most frequent mutation observed. Cancer Lett 2002;185:61-70.