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Mathew M, Takagi S: Crystal structures of calcium orthophosphates. Monogr Oral Sci 2001, 18:1-16. An extensive review of the chemistry of calcium phosphates is presented that provides insight into structure-related properties for biomineralization.
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Monogr Oral Sci
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Mathew, M.1
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Calcium pyrophosphate crystal formation and dissolution
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Scanning electron microscopy and molecular modeling of calcium oxafate monohydrate crystal growth inhibition by citrate and phosphocitrate
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Sallis JD, Wierzbicki A, Cheung HS: Calcium pyrophosphate crystal salt forms and the influence of phosphocitrate. In Advances in Crystal Growth Inhibition Technologies. Edited by Amjad Z. New York: Kluwer Academic/Plenum; 2001:57-70. This study reports the alteration of crystal habit by phosphocitrate of various calcium pyrophosphate salt forms. It describes important chemical properties of phosphocitrate and demonstrates the power of molecular modeling.
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Advances in Crystal Growth Inhibition Technologies
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Sallis, J.D.1
Wierzbicki, A.2
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Wierzbicki A, Cheung HS: Molecular modeling of inhibition of hydroxyapatite crystals by phosphocitrate. J Mol Structure Theochem 2001, 529:73-82. Changes that might be expected when phosphocitrate interacts with hydroxyapatite are discussed in a theoretical context and now require experimental evidence to confirm.
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Wierzbicki, A.1
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Structure/performance relationships of phosphorous and carboxyl containing additives as calcium phosphate crystal growth inhibitors
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Sallis JD: Structure/performance relationships of phosphorous and carboxyl containing additives as calcium phosphate crystal growth inhibitors. In: Calcium Phosphates in Biological and Industrial Systems. Edited by Amjad Z. Norwell: Kluwer Academic; 1997:173-191.
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Phosphocitrate as a potential therapeutic strategy for crystal deposition disease
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Cheung HS: Phosphocitrate as a potential therapeutic strategy for crystal deposition disease. Curr Rheumatol Rep 2001, 3:24-28. This paper summarizes many of phosphocitrate's actions with respect to its hydroxyapatite and CPPD crystal-inhibiting ability. The potential to become a therapeutic agent for crystal deposition disease is discussed.
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Curr Rheumatol Rep
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Cheung, H.S.1
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Nair D, Misra RP, Sallis JD, et al.: Phosphocitrate inhibits a basic calcium phosphate and calcium pyrophosphate dihydrate crystal-induced mitogen-activated protein kinase cascade signal transduction pathway. J Biol Chem 1997, 272:18920-18925.
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The ank gene story
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Ryan LR: The ank gene story. Arthritis Res 2001, 3:77-79. Generation and delivery of pyrophosphate to enable crystallization are discussed. The unresolved questions posed are a stimulus inviting new research directions.
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Arthritis Res
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Ryan, L.R.1
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Yamakawa K, Iwasaki H, Masuda I, et al.: Cartilage intermediate layer protein expression in calcium pyrophosphate disease. J Reumatol 2002, 29:1746-1753.
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0035199295
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The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles
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Johnson K, Pritzker K, Goding J, et al.:The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles. J Rheumatol 2001, 28:2681-2691.
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Animal models of pathologic calcification
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Masuda I, Hirose J: Animal models of pathologic calcification. Curr Opin Rheumatol 2002, 14:287-291.
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Synovial fluid basic calcium phosphate (BCP) crystals in an osteoarthritis (OA) canina model
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Altman RD, Cheung HS: Synovial fluid basic calcium phosphate (BCP) crystals in an osteoarthritis (OA) canina model [abstract]. Osteoarthritis Cartilage 1997, 5:48.
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Apatite crystal clumps in synovial fluid are an early finding in canine arthritis
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Inhibitory effect of low density lipoprotein in the inflammation inducing activity of calcium pyrophosphate dihydrate crystals
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Kumagai Y, Watanabe W, Kobayashi A, et al.: Inhibitory effect of low density lipoprotein in the inflammation inducing activity of calcium pyrophosphate dihydrate crystals. J Rheumatol 2001, 28:2674-2680. Low density lipoprotein by binding to crystals is considered an antiinflammatory agent. Because a rat air pouch model is used, it is difficult to consider that altering low density lipoprotein levels in humans would provide effective therapy.
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J Rheumatol
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A crystallographically characterized nine-coordinated calcium-phosphocitrate complex as calcification inhibitor in vivo
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Demadis KD, Sallis JD, Raptis RG, et al.: A crystallographically characterized nine-coordinated calcium-phosphocitrate complex as calcification inhibitor in vivo. J Am Chem Soc 2001, 123:10129-10130. A significant paper describes the formulation of a calcium-sodium phosphocitrate salt with more potent biologic activity than tetrasodium phosphocitrate.
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J Am Chem Soc
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Calcium pyrophosphate dihydrate (CPPD) crystal dissolution by alkaline phosphatase: Interaction of alkaline phosphatase on CPPD crystals
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