Adenovirus with insertion-mutated E1A selectively propagates in liver cancer cells and destroys tumors in vivo

Cancer Research

Volumn 63, Issue 12, 2003, Pages 3073-3078

  Zhao, Tiejun ^a,c   Rao, Xiao Mei ^e   Xie, Xiaoming ^b   Li, Ling ^a   Thompson, Timothy C ^b   McMasters, Kelly M ^e   Zhou, Heshan Sam ^d  

^a CENTER FOR CELL AND GENE THERAPY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^d UNIVERSITY OF LOUISVILLE   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; DNA FRAGMENT; E1A PROTEIN; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL STRAIN HEP3B; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA REPLICATION; EMBRYO; EMBRYONAL CARCINOMA; GENE INSERTION; GENE MUTATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER CANCER; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; UNDIFFERENTIATED CARCINOMA; VIRAL GENE THERAPY; VIRUS REPLICATION;

ADENOVIRUS E1A PROTEINS; ANIMALS; BIOLOGICAL THERAPY; CARCINOMA, HEPATOCELLULAR; CYTOPATHOGENIC EFFECT, VIRAL; DEFECTIVE VIRUSES; DNA, VIRAL; HUMANS; LIVER NEOPLASMS; MASTADENOVIRUS; MICE; MICE, NUDE; MUTAGENESIS, INSERTIONAL; TUMOR CELLS, CULTURED; VIRUS INTEGRATION; VIRUS REPLICATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0037732474     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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