Increased expression of intracellular HLA-DM but not on the surface of blood monocyte-derived dendritic cells during maturation

Yonsei Medical Journal

Volumn 44, Issue 2, 2003, Pages 293-298

  Kang, Jin Moon ^a   Chung, Han Gil ^a   Oh, Sang Joon ^a   Song, Seung Yong ^a   Lee, Tae Hyung ^a   Lee, Min Geol ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Antigen presentation; HLA DM; MHC class II molecules; Monocyte derived dendritic cell

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DM ANTIGEN; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CELL CULTURE; CELL MATURATION; CELL SURFACE; CONTROLLED STUDY; DENDRITIC CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INTRACELLULAR SPACE; LANGERHANS CELL; MONOCYTE;

EID: 0037720076     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2003.44.2.293     Document Type: Article

References (33)

1. Austyn JM. Dendritic cells. Curr Opin Hematol 1998;5: 3-15.
2. Cumberbatch M, Dearman RJ, Griffiths CE, Kimber I. Langerhans cell migration. Clin Exp Dermatol 2000; 25:413-8.
3. Cerio R, Griffiths CE, Cooper KD, Nickoloff BJ, Headington JT. Characterization of factor XIIIa positive dermal dendritic cells in normal and inflamed skin. Br J Dermatol 1989;121:421-31.
4. Nestle FO, Zheng XG, Thompson CB, Turka LA, Nickoloff BJ. Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets. J Immunol 1993; 151:6535-45.
5. McLellan AD, Heiser A, Sorg RV, Fearnley DB, Hart DN. Dermal dendritic cells associated with T lymphocytes in normal human skin display an activated phenotype. J Invest Dermatol 1998;111:841-9.
6. Steinman RM. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 1991;9:271-96.
7. Larsen CP, Morris PJ, Austyn JM. Migration of dendritic leukocytes from cardiac allograft into host spleens: a novel pathway for initiation of rejection. J Exp Med 1990;171:307-14.
8. Cameron PU, Freudenthal PS, Barker JM, Gezelter S, Inaba K, Steinman RM. Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4 T cells. Science 1992;257:383-7.
9. Austyn JM. Antigen uptake and presentation by dendritic leukocytes. Semin Immunol 1992;4:227-36.
10. Austyn JM. New insights into the mobilization and phagocytic dendritic cells. J Exp Med 1996;183:1287-92.
11. Banchereau J, Steinman RM. Dendritic cells and the control immunity. Nature 1998;392:245-52.
12. Sallusto F, Cella M, Danieli C, Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate antigen to the MHC class II compartment. Downregulation by cytokines and bacterial products. J Exp Med 1995;182:389-400.
13. Jiang W, Swiggard WJ, Heafler C, Peng M, Mirza A, Steinman RM, et al. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 1995;374:151-5.
14. Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 1994;179:1109-18.
15. Winzler C, Rovere P, Rescigno M, Granucci F, Penna G, Adorini L, et al. Maturation states of mouse dendritic cells in growth factor-dependent long-term cultures. J Exp Med 1997;185:317-28.
16. Buelens C, Verhasselt V, De Groote D, Thielemans K, Goldman M, Willems F. Human dendritic cells response to lipopolysaccharide and CD 40 ligation are differentially regulated by IL-10. Eur J Immunol 1997; 27:1848-52.
17. Reid CD, Stackpoole A, Meager A, Tikerpae J. Interactions of tumor necrosis factor with granulocyte-macrophage conlony stimulating factor and other cytokines in the regulation of dendritic cell growth in vitro from early bipotent CD34+ progenitors in human bone marrow. J Immunol 1992;149:2681-8.
18. Egner W, Hart DN. The phenotypes of freshly isolated and cultured human bone marrow allostimulatory cells: Possible heterogeneity in bone marrow dendritic cell populations. Immunology 1995;85:611-20.
19. Caux C, Dezutter-Dambuyant C, Schmitt D, Banchereau J. GM-CSF and TNF- α cooperate in the generation of dendritic Langerhans cells. Nature 1992;360:258-61.
20. Gluckman JC, Rosenzwajg M, Canque B. Human dendrtic cell differentiation pathway from CD34+ hematopoietic precursor cells. Blood 1996;87:535-44.
21. Romani N, Gruner S, Brang D, Kampgen E, Lenz A, Trockenbacher B, et al. Proliferating dendritic cell progenitors in human blood. J Exp Med 1994;180:83-93.
22. Choi GS, Kang JM, Lee MG. Analysis of methods for the generation of dendritic cells from human peripheral blood monocytes. Yonsei Med J 2000;41:642-50.
23. Grassi F, Dezutter-Dambuyant C, McIlroy D, Jacquet C, Yoneda K, Imamura S, et al. Monocyte-derived dendritic cells have a phenotype comparable to that of dermal dendritic cells and display ultrastructural granules distinct from Birbeck granules. J Leukoc Biol 1998;64:484-93.
24. Romani N, Reider D, Heuer M, Ebner S, Kampgen E, Eibl B, et al. Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J Immunol Methods 1996;196:137-51.
25. Kropshofer H, Hammerling GJ, Vogt AB. How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest?. Immunol Today 1997;18:77-82.
26. Sanderson F, Kleijmeer MJ, Kelly A. Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments. Science 1994;266:1566-9.
27. Karlsson L, Peleraux A, Lindstedt R, Liljedahl M, Peterson PA. Recognition of an operational MHC class II compartment in nonantigen-presenting cells. Science 1994;266:1569-73.
28. Jonuleit H, Kuhn U, Muller G, Steinbrink K, Pragnik L, Schmit E, et al. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur J Immunol 1997;27:3135-42.
29. Julius MH, Simpson E, Herzenberg LA. A rapid method for the isolation of functional thymus-derived murine lymphocytes. Eur J Immunol 1973;3:645-9.
30. Sato K, Nagayama H, Tadokoro K, Juji T, Takahashi TA. Interleukin-13 is involved in functional maturation of human peripheral blood monocyte-derived dendritic cells. Exp Hematol 1999;27:326-36.
31. Sallusto F, Nicolo C, De Maria R, Corinti S, Testi R. Ceramide inhibits antigen uptake and presentation by dendritic cells. J Exp Med 1996;184:2411-6.
32. Caux C, Massacrier C, Vanbervliet B, Dubois B, Van Kooten C, Durand I, et al. Activation of human dendritic cells through CD40 cross-linking. J Exp Med 1994;180:1263-72.
33. Arndt SO, Vogt AB, Markovic-Plese S, Martin R, Moldenhauer G, Wolpl A, et al. Functional HLA-DM on the surface of B cells and immature dendritic cells. EMBO J 2000;19:1241-51.