A study on the activation peptide released from procarboxypeptidase B (CAPAP) and anionic trypsinogen in patients with acute abdominal disorders of non-pancreatic origin

Pancreatology

Volumn 3, Issue 2, 2003, Pages 149-155

  Müller, Christophe A ^a   Appelros, Stefan ^b   Uhl, Waldemar ^a   Büchler, Markus W ^a   Borgström, Anders ^b  

^a UNIVERSITY OF BERN   (Switzerland)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Acute pancreatitis; Anionic trypsinogen; CAPAP; Carboxypeptidase B, activation peptide

Indexed keywords

ANION; PEPTIDASE; PEPTIDE; PROCARBOXYPEPTIDASE B; TRYPSINOGEN; UNCLASSIFIED DRUG;

ACUTE ABDOMEN; ACUTE PANCREATITIS; ADULT; AGED; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISEASE ASSOCIATION; DISEASE MARKER; DISEASE SEVERITY; ENZYME BLOOD LEVEL; ENZYMURIA; FEMALE; HUMAN; IMMUNOASSAY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; URINALYSIS;

EID: 0037719634     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1159/000070084     Document Type: Article

References (19)

1. Polloc AV: Acute pancreatitis. Analysis of 100 patients. Br Med J 1959;i:6-14.
2. Heat DI, Cruickshank A, Gudgeon AM, et al: The relationship between pancreatic enzyme release and activation and the acute-phase protein response in patients with acute pancreatitis. Pancreas 1995;10:347-353.
3. Ranson JH, Rifkind KM, Roses DF, et al: Objective early identification of severe acute pancreatitis. Am J Gastroenterol 1974;61:443-451.
4. Ohlsson K, Balldin G, Bohe M, Borgström A, Genell S, Lasson Å.: Pancreatic proteases and antiproteases in pancreatic disease: Biochemical, pathophysiological and clinical aspects. Int J Pancreatol 1988;3:67-78.
5. Whitcomb DC: Hereditary pancreatitis: New insights into acute and chronic pancreatitis. Gut 1999;79:317-322.
6. Gudgeon AM, Heath DI, Hurley P, et al: Trypsinogen activation peptides assay in the early prediction of severity in acute pancreatitis. Lancet 1990;335:4-8.
7. Tenner S, Fernandez-del Castillo C, Warshaw A, Steinberg W, Hermon-Taylor J, Valenzuela JE, Hariri M, Hughes M, Banks PA: Urinary trypsinogen activation peptide (TAP) predicts severity in patients with acute pancreatitis. Int J Pancreatol 1997;21:105-110.
8. Neoptolemos JP, Kemppainen EA, Mayer JM, et al: Early prediction of severity in acute pancreatitis by urinary trypsinogen activation peptide: A multicentre study. Lancet 2000;355:1955-1960.
9. Appelros S, Thim L, Borgström A: Activation peptide in carboxypeptidase B in serum and urine in acute pancreatitis. Gut 1998;42:97-102.
10. Appelros S, Pettersson U, Toh S, et al: Activation peptide of carboxypeptidase B (CAPAP) and anionic trypsinogen as early predictors of severity of acute pancreatitis. Br J Surg 2001;88:216-221.
11. Banks PA, Carr-Locke DL, Slivka A, et al: Urinary trypsinogen activation peptides (TAP) are not increased in mild ERCP-induced pancreatitis. Pancreas 1996;12:294-297.
12. Pettersson U, Appelros S, Borgström A: Different patterns in immunoreactive anionic and cationic trypsinogen in urine and serum in human pancreatitis. Int J Pancreatol 1999;25:165-170.
13. Hedström J, Sainio V, Kemppainen E, et al: Urine trypsinogen-2 as a marker of acute pancreatitis. Clin Chem 1996;42:685-690.
14. Hedström J, Korvuo A, Kenkimaki P, et al: Urinary trypsinogen-2 test strip for acute pancreatitis. Lancet 1996;347:729-730.
15. Sainio V, Puolakkainen P, Kemppainen E, et al: Serum trypsinogen-2 in the prediction of outcome in acute necrotizing pancreatitis. Scand J Gastroenterol 1996;31:818-824.
16. Knaus WA, Draper EA, Wagner DP, et al: APACHE II: A severity of disease classification system. Crit Care Med 1985;13:818-829.
17. Kimland M, Russik C, Marks WH, Borgström A: Immunoreactive anionic and cationic trypsin in human serum. Clin Chim Acta 1989;184:31-46.
18. Itkonen O, Koivunen E, Hurme M, et al: Time-resolved immunofluorometric assays for trypsinogen-1 and -2 in serum reveal preferential elevation of trypsinogen-2 in pancreatitis. J Lab Clin Chem 1990;115:712-718.
19. Kemppainen EA, Hedstrom JI, Puolakkainen PA, et al: Rapid measurement of urinary trypsinogen-2 as a screening test for acute pancreatitis. N Engl J Med 1997;336:1788-1793.