Serum trypsinogen-2 in the prediction of outcome in acute necrotizing pancreatitis

Scandinavian Journal of Gastroenterology

Volumn 31, Issue 8, 1996, Pages 818-824

  Sainio, V ^a   Puolakkainen, P ^b   Kemppainen, E ^b   Hedstrom J ^b   Haapiainen, R ^b   Kivisaari, L ^b   Stenman, U H ^b   Schroder T ^b   Kivilaakso, E ^b  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b NONE

Author keywords

Acute pancreatitis; Amylase; C reactive protein; Necrosis; Severity; Trypsinogen 2

Indexed keywords

AMYLASE; C REACTIVE PROTEIN; IOHEXOL; MEGLUMINE IOTALAMATE; TRYPSINOGEN;

ACUTE PANCREATITIS; ADULT; ALCOHOL CONSUMPTION; ARTICLE; ASSISTED VENTILATION; AUTOPSY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FLUOROIMMUNOASSAY; HUMAN; KIDNEY FAILURE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; PANCREAS NECROSIS; PRIORITY JOURNAL; PROGNOSIS; RESPIRATORY FAILURE; RESUSCITATION;

EID: 0030016629     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365529609010359     Document Type: Article

References (35)

1. Clavien PA, Robert J, Meyer P, Borst F, Hauser H, Herrmann F, et al. Acute pancreatitis and normoamylasemia. Not an uncommon combination. Ann Surg 1989;210:614-20.
2. Winslet M, Hall C, London NJ, Neoptolemos JP. Relation of diagnostic serum amylase levels to aetiology and severity of acute pancreatitis. Gut 1992;33:982-6.
3. Kivisaari L, Somer K, Standertskjold NC, Schroder T, Kivilaakso E, Lempinen M. A new method for the diagnosis of acute hemorrhagic-necrotizing pancreatitis using contrast-enhanced CT. Gastrointest Radiol 1984;9:27-30.
4. Kivisaari L, Somer K, Standertskjold NC, Schroder T, Kivilaakso E, Lempinen M. Early detection of acute fulminant pancreatitis by contrast-enhanced computed tomography. Scand J Gastroenterol 1983;18:39-41.
5. Clavien PA, Hauser H, Meyer P, Rodner A. Contrast-enhanced CT scan in the early phase of acute pancreatitis [letter; comment]. Br J Surg 1989;76:878-9.
6. London NJ, Neoptolemos JP, Lavelle J, Bailey I, James D. Contrast-enhanced abdominal computed tomography scanning and prediction of severity of acute pancreatitis: a prospective study [comments]. Br J Surg 1989;76:268-72.
7. Schroder T, Kivisaari L, Somer K, Standertskjold NC, Kivilaakso E, Lempinen M. Significance of extrapancreatic findings in computed tomography (CT) of acute pancreatitis. Eur J Radiol 1985;5:273-5.
8. Steer ML, Meldolesi J. Pathogenesis of acute pancreatitis. Annu Rev Med 1988;39:95-105.
9. Castillo FC, Schmidt J, Warshaw AL, Rattner DW. Interstitial protease activation is the central event in progression to necrotizing pancreatitis. Surgery 1994;116:497-504.
10. Hedström J, Leinonen J, Sainio V, Stenman U. Time-resolved immunofluorometric assay of trypsin-2 complexed with a-antitrypsin in serum. Clin Chem 1994;40:1761-5.
11. Itkonen O, Koivunen E, Hurme M, Alfthan H, Schroder T, Stenman UH. Time-resolved immunofluorometric assays for trypsinogen-1 and 2 in serum reveal preferential elevation of trypsinogen-2 in pancreatitis. J Lab Clin Med 1990;115: 712-8.
12. Kimland M, Russick C, Marks WH, Borgstrom A. Immuno-reactive anionic and cationic trypsin in human serum. Clin Chim Acta 1989;184:31-46.
13. Henkel E, Morich S, Henkel R. 2-Chloro-4-nitrophenyl-b-D-maltoheptaoside: a new substrate for the determination of a-amylase in serum and urine. J Clin Chem Clin Biochem 1984; 22:489-95.
14. Hemmila I, Dakubu S, Mukkala VM, Siitari H, Lovgren T. Europium as a label in time-resolved immunofluorometric assays. Anal Biochem 1984;137:335-43.
15. Alfthan H, Stenman UH. Purification of labelled antibodies by hydrophobic interaction chromatography. J Chromatogr 1989; 470:385-9.
16. Zweig MH, Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem 1993;39:561-77.
17. Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982; 143:29-36.
18. Borgstrom A, Lasson A, Ohlsson K. Patterns of immunoreactive trypsin in serum from patients with acute abdominal disorders. Scand J Clin Lab Invest 1989;49:757-62.
19. Mero M, Tenhunen R, Pessi T, Sandholm M. Serum immunoreactive trypsin and trypsin inhibitors during acute pancreatitis. Ann Chir Gynaecol 1980;69:251-5.
20. Hill MC, Huntington DK. Computed tomography and acute pancreatitis. Gastroenterol Clin North Am 1990;19:811-42.
21. London NJ, Leese T, Lavelle JM, Miles K, West KP, Watkin DF, et al. Rapid-bolus contrast-enhanced dynamic computed tomography in acute pancreatitis: a prospective study. Br J Surg 1991;78:1452-6.
22. Kivisaari L, Schroder T, Sainio V, Somer K, Standertskjold NC. CT evaluation of acute pancreatitis: 8 years clinical experience and experimental evidence. Acta Radiol [Diagn] (Stockh) 1991; 377 Suppl 20:20-4.
23. Puolakkainen PA. Early assessment of acute pancreatitis. A comparative study of computed tomography and laboratory tests. Acta Chir Scand 1989;155:25-30.
24. Steinberg WM. Predictors of severity of acute pancreatitis. Gastroenterol Clin North Am 1990;19:849-61.
25. Iovanna JL, Keim V, Nordback I, Montalto G, Camarena J, Letoublon C, et al. Serum levels of pancreatitis-associated protein as indicators of the course of acute pancreatitis. Multicentric Study Group on Acute Pancreatitis. Gastroenterology 1994;106:728-34.
26. Dominguez MJ, Carballo F, Garcia MJ, de Diego JM, Rahago L, Simon MA, et al. Clinical usefulness of polymorphonuclear elastase in predicting the severity of acute pancreatitis: results of a multicentre study. Br J Surg 1991;78:1230-4.
27. Gross V, Leser HG, Heinisch A, Scholmerich J. Inflammatory mediators and cytokines - new aspects of the pathophysiology and assessment of severity of acute pancreatitis? Hepatogastroenterology 1993;40:522-30.
28. Ogawa M. Pancreatic secretory trypsin inhibitor as an acute phase reactant. Clin Biochem 1988;21:19-25.
29. Wilson C, Imrie CW. Deaths from acute pancreatitis: why do we miss the diagnosis so frequently? Int J Pancreatol 1988;3: 273-81.
30. Apple F, Benson P, Preese L, Eastep S, Bilodeau L, Heiler G. Lipase and pancreatic amylase activities in tissues and in patients with hyperamylasemia. Am J Clin Pathol 1991;96: 610-4.
31. Gumaste V, Dave P, Sercny G. Serum lipase: a better test to diagnose acute alcoholic pancreatitis. Am J Med 1992;92: 239-42.
32. Agarwal N, Pitchumoni CS, Sivaprasad AV. Evaluating tests for acute pancreatitis. Am J Gastroenterol 1990;85:356-66.
33. Lucarotti ME, Virjee J, Alderson D. Patient selection and timing of dynamic computed tomography in acute pancreatitis. Br J Surg 1993;80:1393-5.
34. Tervahartiala P, Kivisaari L, Virtanen I. Contrast media-induced renal morphologic changes in rats with acute edematous pancreatitis. Invest Radiol 1992;27:520-4.
35. Gudgeon AM, Heath DI, Hurley P, Jehanli A, Patel G, Wilson C, et al. Trypsinogen activation peptidcs assay in the early prediction of severity of acute pancreatitis. Lancet 1990;335: 4-8.