Plasma levels of parathyroid hormone (1-84) whole molecule and parathyroid hormone (7-84)-like fragments in pseudohypoparathyroidism type I

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 5, 2003, Pages 2250-2255

  Hatakeyama, Yuriko ^a   Mizunashi, Kazutoshi ^b   Furukawa, Yohtaro ^c   Yabuki, Shigemitsu ^a   Sato, Yumi ^a   Igarashi, Teruo ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Sen en General Hospital   (Japan)

^c Department of Laboratory Medicine JCHOSendai Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CALCIUM; PARATHYROID HORMONE; PARATHYROID HORMONE[1-34]; PARATHYROID HORMONE[7-84]; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CALCIUM BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; FEMALE; HORMONE ACTION; HORMONE BLOOD LEVEL; HORMONE DETERMINATION; HORMONE RESPONSE; HUMAN; HYPERPHOSPHATEMIA; HYPOCALCEMIA; MALE; NUCLEOTIDE SEQUENCE; PARATHYROID HORMONE BLOOD LEVEL; PARATHYROID HORMONE RELEASE; PRIORITY JOURNAL; PSEUDOHYPOPARATHYROIDISM; STIMULATION; THYROID HORMONE RESISTANCE;

ADOLESCENT; CALCITRIOL; CALCIUM; DRUG RESISTANCE; FEMALE; HUMANS; HYPOCALCEMIA; MALE; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; PHOSPHATES; PSEUDOHYPOPARATHYROIDISM; REFERENCE VALUES;

EID: 0037692885     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-021610     Document Type: Article

References (15)

1. John MR, Goodman WG, Gao P, Cantor TL, Salusky IB, Juppner H 1999 A novel immunoradiometric assay detects full-length human PTH but not amino-terminally truncated fragments: implications for PTH measurements in renal failure. J Clin Endocrinol Metab 84:4287-4290
2. Gao P, Scheibel S, D'Amour P, John MR, Rao SD, Schmidt-Gayk H, Cantor TL 2001 Development of a novel immunoradiometric assay exclusively for biologically active whole parathyroid hormone 1-84: implications for improvement of accurate assessment of parathyroid function. J Bone Miner Res 16:605-614
3. Guthrie E, Lu J, Cody C, Hutchison JS, Wong J, Carlton E, Caufield M, Nelson J, Reitz RE, Fisher DA, Segre G 2001 Development of an automated assay that measures PTH with no crossreactivity to non-(1-84) PTH. Program of the 83rd Annual Meeting of The Endocrine Society, Denver, CO, 2001, p 473 (Abstract P3-115)
4. Lepage R, Roy L, Brossard JH, Rousseau L, Dorais C, Lazure C, D'Amour P 1998 A non-(1-84) circulating parathyroid hormone (PTH) fragment interferes significantly with intact PTH commercial assay measurements in uremic samples. Clin Chem 44:805-809
5. Slatopolsky E, Finch J, Clay P, Martin D, Sicard G, Singer G, Gao P, Cantor T, Dusso A 2000 A novel mechanism for skeletal resistance in uremia. Kidney Int 58:753-761
6. Goto M, Mizunashi K 2001 Decreased sensitivity of distal nephron and collecting duct to parathyroid hormone on pseudohypoparathyroidism type I. J Am Soc Nephrol 12:1965-1970
7. Mizunashi K, Furukawa Y, Abe K, Yoshinaga K 1993 The relationship between serum intact parathyroid hormone and calcium in idiopathic hypoparathyroidism. Calcif Tissue Int 53:378-383
8. Divieti P, John MR, Juppner H, Bringhurst FR 2002 Human PTH-(7-84) inhibits bone resorption in vitro via actions independent of the type 1 PTH/ PTHrP receptor. Endocrinology 143:171-176
9. Mizunashi K, Sohn HY, Furukawa Y 1988 Effects of active vitamin D3 and parathyroid hormone on the serum osteocalcin in idiopathic hypoparathyroidism and pseudohypoparathyroidism. J Clin Invest 82:861-865
10. Ish-Shalom S, Rao LG, Levine MA, Fraser D, Kooh SW, Josse RG, McBroom R, Wong MM, Murray TM 1996 Normal parathyroid hormone responsiveness of bone-derived cells from a patient with pseudohypoparathyroidism. J Bone Miner Res 11:8-14
11. Yamamoto M, Takuwa Y, Masuko S, Ogata E 1988 Effects of endogenous and exogenous parathyroid hormone on tubular reabsorption of calcium in pseudohypoparathyroidism. Clin Endocrinol Metab 66:618-625
12. Mizunashi K, Sohn HY, Furukawa Y 1990 Heterogeneity of pseudohypo-parathyroidism type I from the aspect of urinary excretion of calcium and serum levels of parathyroid hormone. Calcif Tissue Int 46:227-232
13. Mizunashi K, Furukawa Y, Taguchi K, Kuwahara M 1989 Effects of parathyroid hormone on urinary excretion of N-acetyl-β-D-glucosaminidase in idiopathic hypoparathyroidism and pseudohypoparathyroidism. Calcif Tissue Int 45:375-377
14. 3 treatment in hypoparathyroidism and after parathyroid adenectomy in primary hyperparathyroidism. Calcif Tissue Int 57:30-34
15. Mizunashi K, Furukawa Y, Goto MM, Abe K 1998 Sigmoidal curve shift in idiopathic hypoparathyroidism and pseudohypoparathyroidism. Calcif Tissue Int 62:290-294