A green fluorescent chemosensor for amino acids provides a versatile high-throughput screening (HTS) assay for proteases

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 10, 2003, Pages 1653-1656

  Dean, Kathryn E S ^a   Klein, Gérard ^a   Renaudet, Olivier ^a   Reymond, Jean Louis ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CALCEIN; CHYMOTRYPSIN; GREEN FLUORESCENT PROTEIN; PROTEINASE; SUBTILISIN; TRYPSIN;

ARTICLE; CHEMICAL REACTION; ENZYME ACTIVITY; FLUORESCENCE ANALYSIS; HYDROLYSIS; SENSOR;

BOVINAE;

EID: 0037687921     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00280-4     Document Type: Article

References (19)

1. (a) Tsien, R. Y. In Fluorescent Chemosensors for Ion and Molecule Recognition; Czarnik, A. W., Ed., American Chemical Society: Washington, DC, 1993. (b) de Silva A.P., Gunaratne H.Q.N., Gunnlaugsson T., Huxley A.J.M., McCoy C.P., Rademacher J.T., Rice T.E. Chem. Rev. 97:1997;1515.
2. (a) Tsien, R. Y. In Fluorescent Chemosensors for Ion and Molecule Recognition; Czarnik, A. W., Ed., American Chemical Society: Washington, DC, 1993. (b) de Silva A.P., Gunaratne H.Q.N., Gunnlaugsson T., Huxley A.J.M., McCoy C.P., Rademacher J.T., Rice T.E. Chem. Rev. 97:1997;1515.
3. (a) Campbell, A. M. In Monclonal Antibodies and Immunosensor Technology. van der Vilet, P. C. Ed. Elsevier, Amsterdam, 1991: Chapter 12, p 343. (b) Smith D.S., Al-Hakiem M.H.H., Landon J. Ann. Clin. Biochem. 18:1981;253 (c) Hemmilä I. Clin. Chem. 31:1985;359 (d) Gosling J.P. Clin. Chem. 36:1990;1408 (e) Morgan C.L., Newman D.J., Price C.P. Clin. Chem. 42:1996;193 (f) Gizeli E., Lowe C.R. Curr. Op. Biotech. 7:1996;66.
4. (a) Campbell, A. M. In Monclonal Antibodies and Immunosensor Technology. van der Vilet, P. C. Ed. Elsevier, Amsterdam, 1991: Chapter 12, p 343. (b) Smith D.S., Al-Hakiem M.H.H., Landon J. Ann. Clin. Biochem. 18:1981;253 (c) Hemmilä I. Clin. Chem. 31:1985;359 (d) Gosling J.P. Clin. Chem. 36:1990;1408 (e) Morgan C.L., Newman D.J., Price C.P. Clin. Chem. 42:1996;193 (f) Gizeli E., Lowe C.R. Curr. Op. Biotech. 7:1996;66.
5. (a) Campbell, A. M. In Monclonal Antibodies and Immunosensor Technology. van der Vilet, P. C. Ed. Elsevier, Amsterdam, 1991: Chapter 12, p 343. (b) Smith D.S., Al-Hakiem M.H.H., Landon J. Ann. Clin. Biochem. 18:1981;253 (c) Hemmilä I. Clin. Chem. 31:1985;359 (d) Gosling J.P. Clin. Chem. 36:1990;1408 (e) Morgan C.L., Newman D.J., Price C.P. Clin. Chem. 42:1996;193 (f) Gizeli E., Lowe C.R. Curr. Op. Biotech. 7:1996;66.
6. (a) Campbell, A. M. In Monclonal Antibodies and Immunosensor Technology. van der Vilet, P. C. Ed. Elsevier, Amsterdam, 1991: Chapter 12, p 343. (b) Smith D.S., Al-Hakiem M.H.H., Landon J. Ann. Clin. Biochem. 18:1981;253 (c) Hemmilä I. Clin. Chem. 31:1985;359 (d) Gosling J.P. Clin. Chem. 36:1990;1408 (e) Morgan C.L., Newman D.J., Price C.P. Clin. Chem. 42:1996;193 (f) Gizeli E., Lowe C.R. Curr. Op. Biotech. 7:1996;66.
7. (a) Campbell, A. M. In Monclonal Antibodies and Immunosensor Technology. van der Vilet, P. C. Ed. Elsevier, Amsterdam, 1991: Chapter 12, p 343. (b) Smith D.S., Al-Hakiem M.H.H., Landon J. Ann. Clin. Biochem. 18:1981;253 (c) Hemmilä I. Clin. Chem. 31:1985;359 (d) Gosling J.P. Clin. Chem. 36:1990;1408 (e) Morgan C.L., Newman D.J., Price C.P. Clin. Chem. 42:1996;193 (f) Gizeli E., Lowe C.R. Curr. Op. Biotech. 7:1996;66.
8. (a) Campbell, A. M. In Monclonal Antibodies and Immunosensor Technology. van der Vilet, P. C. Ed. Elsevier, Amsterdam, 1991: Chapter 12, p 343. (b) Smith D.S., Al-Hakiem M.H.H., Landon J. Ann. Clin. Biochem. 18:1981;253 (c) Hemmilä I. Clin. Chem. 31:1985;359 (d) Gosling J.P. Clin. Chem. 36:1990;1408 (e) Morgan C.L., Newman D.J., Price C.P. Clin. Chem. 42:1996;193 (f) Gizeli E., Lowe C.R. Curr. Op. Biotech. 7:1996;66.
9. (a) Bahr N., Tierney E., Reymond J.-L. Tetrahedron Lett. 38:1997;1489 (b) Geymayer P., Bahr N., Reymond J.-L. Chem. Eur. J. 5:1999;1006.
10. (a) Bahr N., Tierney E., Reymond J.-L. Tetrahedron Lett. 38:1997;1489 (b) Geymayer P., Bahr N., Reymond J.-L. Chem. Eur. J. 5:1999;1006.
11. (a) Ait-Haddou H., Wiskur S.L., Lynch V.M., Anslyn E.V. J. Am. Chem. Soc. 123:2001;11296 (b) Wiskur S.L., Ait-Haddou H., Lavigne J.J., Anslyn E.V. Acc. Chem. Res. 34:2001;963 (c) Fabbrizzi L., Marcotte N., Stomeo F., Taglietti A. Angew. Chem. Int. Ed. 41:2002;3811 (d) Hortala M.A., Fabbrizzi L., Marcotte N., Stomeo F., Taglietti A. J. Am. Chem. Soc. 125:2003;20 (e) Fabbrizzi L., Licchelli M., Mancin F., Pizzeghello M., Rabaioli G., Taglietti A., Tecilla P., Tonellato U. Chem. Eur. J. 8:2002;94.
12. (a) Ait-Haddou H., Wiskur S.L., Lynch V.M., Anslyn E.V. J. Am. Chem. Soc. 123:2001;11296 (b) Wiskur S.L., Ait-Haddou H., Lavigne J.J., Anslyn E.V. Acc. Chem. Res. 34:2001;963 (c) Fabbrizzi L., Marcotte N., Stomeo F., Taglietti A. Angew. Chem. Int. Ed. 41:2002;3811 (d) Hortala M.A., Fabbrizzi L., Marcotte N., Stomeo F., Taglietti A. J. Am. Chem. Soc. 125:2003;20 (e) Fabbrizzi L., Licchelli M., Mancin F., Pizzeghello M., Rabaioli G., Taglietti A., Tecilla P., Tonellato U. Chem. Eur. J. 8:2002;94.
13. (a) Ait-Haddou H., Wiskur S.L., Lynch V.M., Anslyn E.V. J. Am. Chem. Soc. 123:2001;11296 (b) Wiskur S.L., Ait-Haddou H., Lavigne J.J., Anslyn E.V. Acc. Chem. Res. 34:2001;963 (c) Fabbrizzi L., Marcotte N., Stomeo F., Taglietti A. Angew. Chem. Int. Ed. 41:2002;3811 (d) Hortala M.A., Fabbrizzi L., Marcotte N., Stomeo F., Taglietti A. J. Am. Chem. Soc. 125:2003;20 (e) Fabbrizzi L., Licchelli M., Mancin F., Pizzeghello M., Rabaioli G., Taglietti A., Tecilla P., Tonellato U. Chem. Eur. J. 8:2002;94.
14. (a) Ait-Haddou H., Wiskur S.L., Lynch V.M., Anslyn E.V. J. Am. Chem. Soc. 123:2001;11296 (b) Wiskur S.L., Ait-Haddou H., Lavigne J.J., Anslyn E.V. Acc. Chem. Res. 34:2001;963 (c) Fabbrizzi L., Marcotte N., Stomeo F., Taglietti A. Angew. Chem. Int. Ed. 41:2002;3811 (d) Hortala M.A., Fabbrizzi L., Marcotte N., Stomeo F., Taglietti A. J. Am. Chem. Soc. 125:2003;20 (e) Fabbrizzi L., Licchelli M., Mancin F., Pizzeghello M., Rabaioli G., Taglietti A., Tecilla P., Tonellato U. Chem. Eur. J. 8:2002;94.
15. (a) Ait-Haddou H., Wiskur S.L., Lynch V.M., Anslyn E.V. J. Am. Chem. Soc. 123:2001;11296 (b) Wiskur S.L., Ait-Haddou H., Lavigne J.J., Anslyn E.V. Acc. Chem. Res. 34:2001;963 (c) Fabbrizzi L., Marcotte N., Stomeo F., Taglietti A. Angew. Chem. Int. Ed. 41:2002;3811 (d) Hortala M.A., Fabbrizzi L., Marcotte N., Stomeo F., Taglietti A. J. Am. Chem. Soc. 125:2003;20 (e) Fabbrizzi L., Licchelli M., Mancin F., Pizzeghello M., Rabaioli G., Taglietti A., Tecilla P., Tonellato U. Chem. Eur. J. 8:2002;94.
16. (a) Klein G., Kaufmann D., Schürch S., Reymond J.-L. Chem. Commun. 2001;561 (b) Klein G., Reymond J.-L. Angew. Chem. Int. Ed. 40:2001;1771.
17. (a) Klein G., Kaufmann D., Schürch S., Reymond J.-L. Chem. Commun. 2001;561 (b) Klein G., Reymond J.-L. Angew. Chem. Int. Ed. 40:2001;1771.
18. (a) Wahler D., Reymond J.-L. Curr. Opin. Chem. Biol. 5:2001;152 (b) Wahler D., Reymond J.-L. Curr. Opin. Biotechnol. 12:2001;535.
19. (a) Wahler D., Reymond J.-L. Curr. Opin. Chem. Biol. 5:2001;152 (b) Wahler D., Reymond J.-L. Curr. Opin. Biotechnol. 12:2001;535.