Gonadotropins and inhibins along the development of a luteinized rat ovarian tumor

Molecular and Cellular Endocrinology

Volumn 203, Issue 1-2, 2003, Pages 137-146

  Hockl, P ^a   Sorianello, E ^a   Chamson Reig, A ^a,b   Ballerini, G ^c   Campo, S ^c   Groome, N ^d   Lux Lantos, V ^a   Libertun, Carlos ^a,b  

^a INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c Centro de Investigaciones Endocrinologicas   (Argentina)

^d OXFORD BROOKES UNIVERSITY   (United Kingdom)

Author keywords

Gonadotropins; Histology; IGF 1; Inhibins; Luteinized ovarian rat tumor

Indexed keywords

FOLLITROPIN; GONADOTROPIN; INHIBIN; INHIBIN A; INHIBIN B; LUTEINIZING HORMONE; MESSENGER RNA; PROTEIN SUBUNIT; SOMATOMEDIN C;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; HORMONAL REGULATION; HORMONE DETERMINATION; LUTEINIZATION; NONHUMAN; NORTHERN BLOTTING; OVARY TUMOR; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; RAT; REGULATORY MECHANISM;

EID: 0037684969     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(03)00085-6     Document Type: Article

References (49)

1. Abel M.H., Wooton A.N., Wilkins V., Huhtaniemi I., Knight P.G., Charlton H.M. The effect of a null mutations in the follicle-stimulating hormone receptor gene on mouse reproduction. Endocrinology. 141:2000;1795-1803.
2. Auersperg N., Edelson M.I., Mok S.C., Johnson S.W., Hamilton T.C. The biology of ovarian cancer. Semin. Oncol. 25:1998;281-304.
3. Barontini M., Garcia-Rudaz M.C., Veldhuis J.D. Mechanisms of hypothalamic-pituitary-gonadal disruption in polycystic ovarian syndrome. Arch. Med. Res. 32:2001;544-552.
4. Bicsak T., Cajander S., Vale W., Hsueh A.J.W. Inhibin: studies of stored and secreted forms by biosynthetic labeling and immunodetection in cultured rat granulosa cells. Endocrinology. 122:1988;741-748.
5. Biskind M., Biskind G. Development of tumors in the rat ovary after transplantation into the spleen. Proc. Soc. Exp. Biol. Med. 55:1944;176-179.
6. Breier B., Gallaher B., Gluckman P. Radioimmunoassay for insulin-like growth factor-1: solutions to some potential problems and pitfalls. J. Endocrinol. 128:1991;347-357.
7. Burton K. A study of conditions and mechanisms of the diphenyl amine reaction for the colorimetric estimation od deoxiribonucleic acid. Biochem. J. 62:1956;315-317.
8. Chamson-Reig A., Lux-Lantos V.A.R., Tesone M., Libertun C. GnRH receptors and GnRH endocrine effects on luteoma cells. Endocrine. 6:1997;165-171.
9. Chamson-Reig A., Bianchi M.S., Rey-Roldán E.B., Sorianello E., Libertun C., Lux-Lantos V.A. Development of an experimental ovarian tumor over a year in the rat. Life Sci. 65:1999;1275-1285.
10. Chamson-Reig A., Pignataro O.P., Libertun C., Lux-Lantos V. Alterations in intracellular messengers mobilized by gonadotropin-releasing hormone in an experimental ovarian tumor. Endocrinology. 140:1999;3573-3580.
11. Danilovich N., Roy I., Sairam M.R. Ovarian pathology and high incidence of sex cord tumors in follitropin receptor knockout (FORKO) mice. Endocrinology. 142:2001;3673-3684.
12. Dierich A., Sairam M.R., Monaco L., Fimia G.M., Gansmuller A., LeMeur M., Sassone-Corsi P. Impairing follicle-stimulating hormone (FSH) signalling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance. Proc. Natl. Acad. Sci. USA. 95:1998;13617.
13. Flemming P., Grothe W., Maschek H., Petry K.U., Wellmann A., Georgii A. The site of inhibin production in ovarian neoplasms. Histopathology. 29:1996;465-468.
14. Foreman D.F., Wilder M. Inhibin is present in the corpus luteum of pseudopregnant rats and can interact with progesterone to inhibit resumption of estrous cycles. Endocr. Res. 21:1995;595-614.
15. Fox H. Sex cord-stromal tumors of the ovary. J. Pathol. 145:1985;127-148.
16. Groome N.P., O'Brien M. Immunoassays for inhibin and its subunits. Further applications of the synthetic peptide approach. J. Immunol. Methods. 165:1993;167-176.
17. Groome N.P., Illingworth P., O'Brien M., Pai R., Rodger F., Mather J., McNeilly A.S. Measurement of dimeric inhibin B throughout the human menstrual cycle. J. Clin. Endocrinol. Metab. 81:1996;1401-1405.
18. Hsueh A.J., Eisenhauer K., Chun S.-Y., Hsu S.Y., Billig H. Gonadal cell apoptosis. Rec. Prog. Horm. Res. 51:2002;433-455.
19. Huhtamiemi I., Zhang F.P., Kero J., Hamalainen T., Poutanen M. Transgenic and knockout mouse models for the study of luteinizing hormone and luteinizing hormone receptor function. Mol. Cell. Endocrinol. 187:2002;49-56.
20. Kananen K., Rilianawati, Paukku T., Markkula M., Rainio E.-M., Huhtamiemi I. Suppression of gonadotropins inhibits gonadal tumorigenesis in mice transgenic for the mouse inhibin α-subunit promoter/Simian virus 40 T-antigen fusion gene. Endocrinology. 138:1997;3521-3531.
21. Kommoss F., Oliva E., Bhan A.K., Young R.H., Scully R.E. Inhibin expression in ovarian tumors and tumor-like lesions: an immunohistological study. Mod. Pathol. 11:1998;656-664.
22. Kumar T., Wang Y., Matzuk M. Gonadotropins are essential modifier factors for gonadal tumor development in inhibin-deficient mice. Endocrinology. 137:1996;4210-4216.
23. Lanari C., Kordon E., Molinolo A., Pasqualini C., Charreau E. Mammary adenocarcinomas induced by medroxyprogesterone acetate: hormone dependence and EGF receptors of BALB/c in vivo sublines. Int. J. Cancer. 43:1989;845-850.
24. Lanuza G., Groome N., Barañao L., Campo S. Dimeric inhibin A and B production are differentially regulated by hormones and local factors in rat granulosa cells. Endocrinology. 140:1999;2549-2554.
25. Leeuwenberg B., Hudson N., Moore L., Hurst P., Mc Natty K. Peripheral and ovarian IGF-1 concentration during the ovine oestrous cycle. J. Endocrinol. 148:1996;281-289.
26. Li D., Kubo T., Kim H., Shimasaki S., Erickson G.F. Endogenous insulin-like growth factor-I is obligatory for stimulation of rat inhibin alpha subunit expression by follicle-stimulating hormone. Biol. Reprod. 58:1998;219-225.
27. Liu J., Yakar S., LeRoith D. Conditional knockout of mouse insulin-like growth factor 1 gene using the Cre/LoxP system. Proc. Soc. Exp. Biol. Med. 223:2000;344-351.
28. Lux V.A.R., Tesone M., Larrea G.A., Libertun C. High correlation between prolactinemia, 125-I hLH binding and progesterone secretion by an experimental luteoma. Life Sci. 35:1984;2345-2352.
29. Lux-Lantos V.A.R., Thyssen S.M., Chamson-Reig A., Libertun C. Effect of a gonadotropin releasing hormone analog on an experimental ovarian tumor: direct and indirect actions. Life Sci. 57:1995;291-300.
30. Matzuk M., Finegold M., Su J., Hsueh A.J.W., Bradley A. inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature. 360:1992;313-319.
31. McCracken J.A., Custer E.E., Lamsa J.C. Luteolysis: a neuroendocrine-mediated event. Physiol. Rev. 79:1999;263-323.
32. Mc Lachlan R., Cohen N.L., Vale W., Rivier C., Burger H.G., Bremner W.J., Soules M.R. The importance of the luteinizing hormone in the control of inhibin and progesterone secretion by the human corpus luteum. J. Clin. Endocrinol. Metab. 68:1989;1078-1085.
33. Ogawa K., Kurohmaru S., Shiota K., Takahashi M., Nishida T., Hayashi Y. Histochemical localization of inhibin and activin alpha, beta A and beta B subunits in rat gonads. J. Vet. Med. Sci. 53:1991;207-212.
34. Owens G., Keri R., Nilson J.H. Ovulatory surges of human CG prevent hormone-induced granulosa cell tumor formation leading to the identification of tumor-associated changes in the transcriptome. Mol. Endocrinol. 16:2002;1230-1242.
35. Petraglia F., Zanin E., Faletti A., Reis F.M. Inhibins: paracrine and endocrine effects in female reproductive function. Curr. Opin. Obstet. Gynecol. 11:1999;241-247.
36. Rahman N., Kananen K., Rilianawati, Paukku T., Mikola M., Markkula M., Hämäläinen T., Huhtaniemi I. Transgenic mouse models for gonadal tumorigenesis. Mol. Cell. Endocrinol. 145:1998;167-174.
37. Rilianawati, Paukku T., Kero J., Zhang F., Rahman N., Kananen K., Huhtaniemi I. Direct luteinizing hormone action triggers adrenocortical tumorigenesis in castrated mice transgenic form the murine inhibin alpha-subunit promoter/simian virus 40 T-antigen fusion gene. Mol. Endocrinol. 12:1998;801-809.
38. Risbridger G.P., Schmitt J.F., Robertson D.M. Activins and inhibins in endocrine and other tumors. Endocr. Rev. 22:2001;836-858.
39. Risma K.A., Clay C.M., Nett T.M., Wagner T., Yun J., Nilson J.H. Targeted overexpression of luteinizinghormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors. Proc. Natl. Acad. Sci. USA. 92:1995;1322-1326.
40. Roberts V., Barth S., El-Roeij A., Yen S.C.C. Expression of inhibin/activin subunits and follistatin messenger ribonucleic acids and proteins in ovarian follicles and the corpus-luteum during the human menstrual cycle. J. Clin. Endocrinol. Metab. 77:1993;1402-1410.
41. Rulli S., Kuorelahti A., Karaer O., Pelliniemi L., Poutanen M., Huhtamiemi I. Reproductive disturbances, pituitary lactotrope adenomas and mammary gland tumors in transgenic female mice producing high levels of human chorionic gonadotropin. Endocrinology. 143:2002;4084-4095.
42. Salazar H., Godwin A.K., Daly M.B., Laub P.B., Hogan W.M., Rosenblum N., Boente M.P., Lynch H.T., Hamilton T.C. Microscopic benign and invasive malignant neoplasms and a cancer-prone phenotype in prophylactic oophprectomies. J. Natl. Cancer Inst. 88:1996;1810-1820.
43. Sorianello, E., Fritz, S., Beyer, C., Hales, D., Mayerhofer, A., Libertun, C., Lux-Lantos, V., 2002. Development of an experimental ovarian tumor: immunocytochemical analysis. Eur. J. Endocrinol., 147, 387-395.
44. Vanttinen T., Liu J., Hyden-Granskog C., Parviainen M., Penttila I., Voutilainen R. Regulation of immunoreactive inhibin A and B secretion in cultured human granulosa-luteal cells by gonadotropins, activin A and insulin-like growth factor type-1 receptor. J. Endocrinol. 167:2000;289-294.
45. Welt C., Smith Z.A., Pauler D.K., Hall J.E. Differential regulation of inhibin A and inhibin B by luteinizing hormone, follicle-stimulating hormone, and stage of follicle development. J. Clin. Endocrinol. Metab. 86:2001;2531-2537.
46. Wise P.M. Neuroendocrine correlates of aging. Conn P.M., Freeman M.E. Neuroendocrinology in Phisiology and Medicine. 2000;371-387 Humana Press, Totowa.
47. Woodruff T.K., D'Agostino J.B., Schwartz N., Mayo K.E. Dynamic changes in inhibin messenger RNAs in rat ovarian follicles during the reproductive cycle. Science. 239:1988;1296-1299.
48. Woodruff T.K., Besecke L.M., Groome N., Draper L.B., Schwartz N.B., Weiss J. Inhibin A and inhibin B are inversely correlated to follicle-stimulating hormone, yet are discordant during the follicular phase of the rat estrous cycle, and inhibin A is expressed in a sexually dimorphic manner. Endocrinology. 137:1996;5463-5467.
49. Young R.H., Scully R.E. Sex cord-stromal and steroid-cell tumors. Rubin S.C., Sutton G.P. Ovarian Cancer. 1993;153-172 McGraw-Hill, New York.